MX2020009648A - Muestreador de lecho fijo y metodos relacionados. - Google Patents

Muestreador de lecho fijo y metodos relacionados.

Info

Publication number
MX2020009648A
MX2020009648A MX2020009648A MX2020009648A MX2020009648A MX 2020009648 A MX2020009648 A MX 2020009648A MX 2020009648 A MX2020009648 A MX 2020009648A MX 2020009648 A MX2020009648 A MX 2020009648A MX 2020009648 A MX2020009648 A MX 2020009648A
Authority
MX
Mexico
Prior art keywords
fixed bed
related methods
sampler
bed sampler
disclosed
Prior art date
Application number
MX2020009648A
Other languages
English (en)
Inventor
José Castillo
Bastien Mairesse
Alex Chatel
Sébastien Jean- Pierre Michel RODRIGUEZ
Alexandre Vanhaver
Original Assignee
Univercells Tech S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univercells Tech S A filed Critical Univercells Tech S A
Priority claimed from PCT/EP2019/056732 external-priority patent/WO2019175442A1/en
Publication of MX2020009648A publication Critical patent/MX2020009648A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C12M25/18—Fixed or packed bed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/46—Means for fastening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/02—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by impregnation, e.g. using swabs or loops
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/18—Rollers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/16—Sterilization

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Se describe un muestreador para usarse con un biorreactor para cultivar un cultivo celular; en una modalidad, el biorreactor incluye un lecho fijo estructurado que incluye una porción de la muestra removible para recuperar una muestra de células del cultivo celular; también se describen los aparatos y métodos relacionados.
MX2020009648A 2018-03-16 2019-03-18 Muestreador de lecho fijo y metodos relacionados. MX2020009648A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862644014P 2018-03-16 2018-03-16
BE2018/5179A BE1026108B1 (fr) 2018-03-16 2018-03-16 Échantillonneur à lit fixe et procédés associés
US201862728405P 2018-09-07 2018-09-07
PCT/EP2019/056732 WO2019175442A1 (en) 2018-03-16 2019-03-18 Fixed bed sampler and related methods

Publications (1)

Publication Number Publication Date
MX2020009648A true MX2020009648A (es) 2021-01-08

Family

ID=62567163

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020009648A MX2020009648A (es) 2018-03-16 2019-03-18 Muestreador de lecho fijo y metodos relacionados.

Country Status (12)

Country Link
US (2) US11946032B2 (es)
EP (1) EP3765591B1 (es)
JP (1) JP7394795B2 (es)
KR (1) KR20210010850A (es)
CN (1) CN112424332A (es)
AU (1) AU2019233738A1 (es)
BE (1) BE1026108B1 (es)
BR (1) BR112020018574A2 (es)
CA (1) CA3093997A1 (es)
MX (1) MX2020009648A (es)
RU (1) RU2020133632A (es)
SG (1) SG11202008803WA (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4320217A1 (en) * 2021-04-06 2024-02-14 Corning Incorporated Cell culture sampling substrate for fixed bed reactor
WO2023101848A1 (en) * 2021-11-30 2023-06-08 Corning Incorporated Cell culture sampling from fixed bed bioreactor methods and apparatus
MX2024009094A (es) 2022-01-26 2024-09-06 Univercells Tech Sa Sistema de prediccion/estimacion de biomasa basado en la deteccion de parametros para biorreactor de lecho fijo y metodos relacionados.
CN114410469A (zh) * 2022-03-15 2022-04-29 同腾新创(苏州)科技有限公司 一种适用于病毒载体生产的可拆卸固定床生物反应器
WO2023249816A1 (en) * 2022-06-22 2023-12-28 Corning Incorporated Fixed bed cell culture reactor vessel for substrate alignment and sampling

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
DE3516080A1 (de) * 1985-05-04 1986-11-06 Proton AG, Zug Probeentnahmesonde
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US4734373A (en) 1986-06-24 1988-03-29 Bartal Arie H Apparatus for enhancing cell growth, preservation and transport
JPH0833474A (ja) * 1994-07-25 1996-02-06 Fuji Photo Film Co Ltd 付着性動物細胞の培養基体
JP4601746B2 (ja) * 1999-10-25 2010-12-22 エイブル株式会社 三次元動物細胞培養装置及び培養方法
DE10335130A1 (de) 2003-07-31 2005-02-24 Blue Membranes Gmbh Immobilisierung von Katalysatoren auf porösen Körpern auf Kohlenstoffbasis
CN2650105Y (zh) * 2003-10-29 2004-10-20 中国科学院电工研究所 生物反应器的在线取样装置
US8505586B2 (en) * 2008-07-18 2013-08-13 Allpure Technologies, Inc. Detachable transfer conduit
US20100099127A1 (en) * 2008-10-21 2010-04-22 Statsure Diagnostic Systems, Inc. System and method for acquiring and storing biological samples
BR112012028786A2 (pt) * 2010-05-11 2015-11-24 Artelis S A biorreator para cultura de células e portador para um biorreator
AU2012241521B2 (en) * 2011-04-15 2016-07-14 Pluri Biotech Ltd Methods and systems for harvesting cells
US20130071872A1 (en) * 2011-09-15 2013-03-21 Lewis Ho Device and method for single-used matrix sampling
US9788820B2 (en) * 2011-12-15 2017-10-17 Femasys Inc Methods and devices for cervical cell and tissue sampling
US9273278B2 (en) * 2013-01-07 2016-03-01 Cesco Bioengineering Co., Ltd. Large scale cell harvesting method for pack-bed culture device
CN203403094U (zh) * 2013-06-27 2014-01-22 上海日泰医药设备工程有限公司 一种生物反应器
GB2520300A (en) * 2013-11-15 2015-05-20 Univ Loughborough Cell Culture System
US10344257B2 (en) * 2015-07-24 2019-07-09 Bioreactor Sciences Llc Horizontally rocked bioreactor system
CN205473765U (zh) * 2016-03-14 2016-08-17 上海康岱生物医药技术股份有限公司 一种单向取样器
CN116144500A (zh) * 2016-04-14 2023-05-23 崔泽尔有限公司 具有恒流泵/管道系统的固定床生物反应器
EP3722435A1 (en) * 2016-04-14 2020-10-14 Trizell Ltd. Fixed-bed bioreactor with constant-flow pump/tubing system
EP4320217A1 (en) 2021-04-06 2024-02-14 Corning Incorporated Cell culture sampling substrate for fixed bed reactor

Also Published As

Publication number Publication date
KR20210010850A (ko) 2021-01-28
JP2021518156A (ja) 2021-08-02
BE1026108A1 (fr) 2019-10-09
US20210009933A1 (en) 2021-01-14
AU2019233738A1 (en) 2020-10-15
US20240200010A1 (en) 2024-06-20
SG11202008803WA (en) 2020-10-29
BE1026108B1 (fr) 2019-10-14
EP3765591B1 (en) 2024-09-18
JP7394795B2 (ja) 2023-12-08
CN112424332A (zh) 2021-02-26
RU2020133632A (ru) 2022-04-18
BR112020018574A2 (pt) 2020-12-29
CA3093997A1 (en) 2019-09-19
US11946032B2 (en) 2024-04-02
EP3765591A1 (en) 2021-01-20

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