MX2020004562A - Compuestos antibacterianos. - Google Patents

Compuestos antibacterianos.

Info

Publication number
MX2020004562A
MX2020004562A MX2020004562A MX2020004562A MX2020004562A MX 2020004562 A MX2020004562 A MX 2020004562A MX 2020004562 A MX2020004562 A MX 2020004562A MX 2020004562 A MX2020004562 A MX 2020004562A MX 2020004562 A MX2020004562 A MX 2020004562A
Authority
MX
Mexico
Prior art keywords
compounds
antibacterial compounds
infections
enterobacteriaceae
compositions
Prior art date
Application number
MX2020004562A
Other languages
English (en)
Spanish (es)
Inventor
Paul Meo
Nawaz Khan
Cedric Charrier
Original Assignee
Discuva Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60664899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2020004562(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Discuva Ltd filed Critical Discuva Ltd
Publication of MX2020004562A publication Critical patent/MX2020004562A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Warehouses Or Storage Devices (AREA)
MX2020004562A 2017-11-03 2018-11-02 Compuestos antibacterianos. MX2020004562A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1718285.8A GB201718285D0 (en) 2017-11-03 2017-11-03 Antibacterial Compounds
PCT/GB2018/053183 WO2019086890A1 (en) 2017-11-03 2018-11-02 Antibacterial compounds

Publications (1)

Publication Number Publication Date
MX2020004562A true MX2020004562A (es) 2020-08-13

Family

ID=60664899

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020004562A MX2020004562A (es) 2017-11-03 2018-11-02 Compuestos antibacterianos.
MX2021010246A MX2021010246A (es) 2017-11-03 2020-07-13 Compuestos antibacterianos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021010246A MX2021010246A (es) 2017-11-03 2020-07-13 Compuestos antibacterianos.

Country Status (22)

Country Link
US (2) US11345694B2 (https=)
EP (2) EP4606375A3 (https=)
JP (2) JP7348897B2 (https=)
KR (1) KR102470319B1 (https=)
CN (1) CN111566099B (https=)
AU (1) AU2018361828B2 (https=)
BR (1) BR112020008531A2 (https=)
CA (1) CA3081423A1 (https=)
CL (2) CL2020001147A1 (https=)
CO (1) CO2020005420A2 (https=)
EA (1) EA202091118A1 (https=)
ES (1) ES3005164T3 (https=)
GB (1) GB201718285D0 (https=)
GE (2) GEAP202315801A (https=)
IL (1) IL274229B2 (https=)
MA (1) MA50504A (https=)
MX (2) MX2020004562A (https=)
PE (2) PE20211390A1 (https=)
SG (1) SG11202003717UA (https=)
UA (1) UA128475C2 (https=)
WO (1) WO2019086890A1 (https=)
ZA (1) ZA202002093B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201718285D0 (en) * 2017-11-03 2017-12-20 Discuva Ltd Antibacterial Compounds
CR20200553A (es) 2018-04-18 2021-04-08 Constellation Pharmaceuticals Inc Moduladores de enzimas modificadoras de metilo, composiciones y usos de estos
CN120097995A (zh) 2018-05-21 2025-06-06 星座制药公司 甲基修饰酶的调节剂、其组合物和用途
WO2021016414A1 (en) 2019-07-24 2021-01-28 Constellation Pharmaceuticals, Inc. Crystalline forms of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-dimethyl-n-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide
CN111635372B (zh) * 2020-06-28 2022-05-27 齐鲁工业大学 一种恶唑酮衍生物及其合成方法
CN117597337A (zh) * 2021-05-03 2024-02-23 迪斯库瓦有限公司 抗菌化合物的制备方法
KR20240004494A (ko) * 2021-05-03 2024-01-11 디스쿠바 엘티디. 항균성 화합물
JP7807529B2 (ja) 2022-02-21 2026-01-27 三井化学株式会社 金属部材、金属樹脂接合体及び金属部材の製造方法
CN118164937A (zh) * 2024-03-13 2024-06-11 北京联本医药化学技术有限公司 一种铵盐离子液体催化制备5-乙酰基-2,3-苯丙二氢呋喃的方法
CN120208965B (zh) * 2025-05-28 2025-08-12 四川大学 靶向革兰氏阴性菌外膜组装关键蛋白质机器的4-(吡啶-4-基)-1h-咪唑-2-胺类衍生物、组合物
CN121471219A (zh) * 2026-01-09 2026-02-06 四川大学 用于革兰氏阴性菌特异性抗菌治疗的咪唑-2-胺类衍生物

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA869348B (en) 1985-12-12 1987-10-28 Smithkline Beckman Corp Inhibition of the 5-lipoxygenase pathway
US4780470A (en) * 1986-08-19 1988-10-25 Smithkline Beckman Corporation Inhibition of interleukin-1 by monocytes and/or macrophages
JP2808460B2 (ja) * 1989-11-16 1998-10-08 大正製薬株式会社 イミダゾール誘導体
JPH09124640A (ja) 1995-08-25 1997-05-13 Nippon Soda Co Ltd ピリジルイミダゾール化合物、製法および農園芸用殺菌剤
US6207687B1 (en) 1998-07-31 2001-03-27 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity
AR029803A1 (es) 2000-02-21 2003-07-16 Smithkline Beecham Plc Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden
EP1532118A2 (en) * 2002-07-05 2005-05-25 Axxima Pharmaceuticals Aktiengesellschaft Imidazole compounds for the treatment of hepatitis c virus infections
JP2004196678A (ja) 2002-12-17 2004-07-15 Dainippon Pharmaceut Co Ltd ピラゾール系誘導体
US8969372B2 (en) 2003-11-14 2015-03-03 Aptose Boisciences Inc. Aryl imidazoles and their use as anti-cancer agents
NZ549003A (en) * 2004-03-05 2009-07-31 Taisho Pharmaceutical Co Ltd Thiazole derivative as an ALK5 inhibitor
JP2007277230A (ja) * 2006-03-15 2007-10-25 Tanabe Seiyaku Co Ltd 医薬組成物
US8865732B2 (en) 2008-03-21 2014-10-21 Novartis Ag Heterocyclic compounds and uses thereof
EP2513064B1 (en) 2009-12-17 2018-07-04 Katholieke Universiteit Leuven K.U. Leuven R&D Compounds, compositions and methods for controlling biofilms
GB201016261D0 (en) 2010-09-28 2010-11-10 Univ Leuven Kath Compounds for controlling biofilms and process for their production
WO2012135016A2 (en) 2011-03-25 2012-10-04 North Carolina State University Inhibition of bacterial biofilms and microbial growth with imidazole derivatives
DK2731949T3 (en) * 2011-07-13 2018-06-14 Tiumbio Co Ltd 2-PYRIDYL-SUBSTITUTED IMIDAZOLS AS ALK5 AND / OR ALK4 INHIBITORS
US8840912B2 (en) 2012-01-09 2014-09-23 North Carolina State University Imidazole derivatives useful for controlling microbial growth
EA039897B1 (ru) * 2014-05-16 2022-03-24 Атрива Терепьютикс Гмбх Применение ингибитора мек для лечения коинфекции, включающей бактериальную инфекцию и инфекцию, вызванную вирусом гриппа
ES2789331T3 (es) 2015-03-02 2020-10-26 Rigel Pharmaceuticals Inc Inhibidores de TGF-beta
WO2016141381A2 (en) 2015-03-05 2016-09-09 University Of Notre Dame Du Lac Potentiators of beta-lactam antibiotics
US10844051B2 (en) 2015-07-22 2020-11-24 The Royal Institution For The Advancement Of Learning/Mcgill University Substituted oxazoles for the treatment of cancer
GB201718285D0 (en) * 2017-11-03 2017-12-20 Discuva Ltd Antibacterial Compounds

Also Published As

Publication number Publication date
EA202091118A1 (ru) 2020-08-06
JP2022025116A (ja) 2022-02-09
MX2021010246A (es) 2021-09-21
NZ764310A (en) 2023-04-28
AU2018361828A1 (en) 2020-05-28
MA50504A (fr) 2020-09-09
KR102470319B1 (ko) 2022-11-25
ES3005164T3 (en) 2025-03-14
US20220372027A1 (en) 2022-11-24
ZA202002093B (en) 2023-11-29
IL274229B2 (en) 2023-05-01
UA128475C2 (uk) 2024-07-24
KR20200084875A (ko) 2020-07-13
JP2021501756A (ja) 2021-01-21
IL274229B1 (en) 2023-01-01
EP4606375A3 (en) 2025-11-19
EP3704105B1 (en) 2024-10-16
AU2018361828B2 (en) 2023-05-18
IL274229A (en) 2020-06-30
GEP20237522B (en) 2023-08-10
EP3704105B9 (en) 2025-03-05
WO2019086890A1 (en) 2019-05-09
GB201718285D0 (en) 2017-12-20
PE20221006A1 (es) 2022-06-15
EP4606375A2 (en) 2025-08-27
JP7348897B2 (ja) 2023-09-21
SG11202003717UA (en) 2020-05-28
EP3704105A1 (en) 2020-09-09
CN111566099A (zh) 2020-08-21
GEAP202315801A (en) 2023-03-27
CL2020001147A1 (es) 2020-08-14
PE20211390A1 (es) 2021-07-27
CA3081423A1 (en) 2019-05-09
CL2021002263A1 (es) 2022-04-01
US20210163460A1 (en) 2021-06-03
US11345694B2 (en) 2022-05-31
BR112020008531A2 (pt) 2020-10-20
CO2020005420A2 (es) 2020-07-31
CN111566099B (zh) 2023-06-02
ES3005164T9 (en) 2025-03-24

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