MX2020003737A - Potenciador para celulas t o celulas b que tienen funcion de memoria, inhibidor de recurrencia de tumor maligno, e inductor para inducir la funcion de memoria en celulas t o celulas b. - Google Patents

Potenciador para celulas t o celulas b que tienen funcion de memoria, inhibidor de recurrencia de tumor maligno, e inductor para inducir la funcion de memoria en celulas t o celulas b.

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Publication number
MX2020003737A
MX2020003737A MX2020003737A MX2020003737A MX2020003737A MX 2020003737 A MX2020003737 A MX 2020003737A MX 2020003737 A MX2020003737 A MX 2020003737A MX 2020003737 A MX2020003737 A MX 2020003737A MX 2020003737 A MX2020003737 A MX 2020003737A
Authority
MX
Mexico
Prior art keywords
cells
memory function
nucleic acid
malignant tumor
enhancer
Prior art date
Application number
MX2020003737A
Other languages
English (en)
Inventor
Koji Tamada
Yukimi Sakoda
Keishi Adachi
Takafumi Nakamura
Original Assignee
Univ Yamaguchi
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Filing date
Publication date
Application filed by Univ Yamaguchi filed Critical Univ Yamaguchi
Publication of MX2020003737A publication Critical patent/MX2020003737A/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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Abstract

Un objeto de la presente invención es proporcionar un potenciador para células T endógenas o células B que tienen una función de memoria y un inhibidor de recurrencia de tumor maligno para continuar rechazando el tumor maligno durante un largo periodo de tiempo; un potenciador para células T o células B que tienen una función de memoria en un sujeto de administración, que comprende un vehículo de administración de ácido nucleico, un ácido nucleico que codifica interleucina-7 (IL-7) y un ligando 19 (motivo C-C) de quimiocina que codifica el ácido nucleico (CCL19), y se prepara un inductor para inducir una función de memoria en células T o células B en un sujeto de administración; además, se prepara un inhibidor de recurrencia de tumor maligno que comprende un vehículo de administración de ácido nucleico, un ácido nucleico que codifica interleucina-7 (IL-7) y un ácido nucleico que codifica CCL19.
MX2020003737A 2017-10-10 2018-10-09 Potenciador para celulas t o celulas b que tienen funcion de memoria, inhibidor de recurrencia de tumor maligno, e inductor para inducir la funcion de memoria en celulas t o celulas b. MX2020003737A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017196718 2017-10-10
PCT/JP2018/037608 WO2019073973A1 (ja) 2017-10-10 2018-10-09 メモリー機能を有するｔ細胞又はｂ細胞の増強剤、悪性腫瘍再発抑制剤、及びｔ細胞又はｂ細胞にメモリー機能を誘導する誘導剤

Publications (1)

Publication Number Publication Date
MX2020003737A true MX2020003737A (es) 2020-08-03

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MX2020003737A MX2020003737A (es) 2017-10-10 2018-10-09 Potenciador para celulas t o celulas b que tienen funcion de memoria, inhibidor de recurrencia de tumor maligno, e inductor para inducir la funcion de memoria en celulas t o celulas b.

Country Status (16)

Country Link
US (1) US11617765B2 (es)
EP (2) EP4265634A3 (es)
JP (2) JP7232447B2 (es)
KR (1) KR20200068661A (es)
CN (1) CN111163758A (es)
AU (2) AU2018349889B2 (es)
BR (1) BR112020006746A2 (es)
CA (1) CA3075886A1 (es)
CL (1) CL2020000950A1 (es)
ES (1) ES2970282T3 (es)
IL (2) IL273689B2 (es)
MX (1) MX2020003737A (es)
PH (1) PH12020550241A1 (es)
SG (1) SG11202003252TA (es)
WO (1) WO2019073973A1 (es)
ZA (1) ZA202000986B (es)

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MX2020006666A (es) * 2017-12-24 2020-08-31 Noile Immune Biotech Inc Celula inmunocompetente que expresa una molecula de superficie celular que reconoce especificamente la mesotelina humana, il-7 y ccl19.
CA3156231A1 (en) 2019-10-28 2021-05-06 Koji Tamada Drug for treating cancer, combination drug, drug composition, immune responsive cell, nucleic acid delivery vehicle, and product
WO2021193081A1 (ja) * 2020-03-23 2021-09-30 国立大学法人東海国立大学機構 １型単純ヘルペスウイルス
CN111849910B (zh) * 2020-05-27 2021-06-15 南京北恒生物科技有限公司 工程化免疫细胞及其用途
CN114717203B (zh) * 2020-12-22 2023-06-27 广东东阳光药业有限公司 一种hIL7/hCCL19双基因重组溶瘤病毒及其制备方法和用途
WO2023007431A1 (en) * 2021-07-29 2023-02-02 Takeda Pharmaceutical Company Limited Engineered immune cell that specifically targets mesothelin and uses thereof
CN113832115A (zh) * 2021-08-25 2021-12-24 居颂光 融合基因ril-7联合ccl19重组溶瘤牛痘病毒及其在制备抗肿瘤药物中的应用
GB202205572D0 (en) 2022-04-14 2022-06-01 Adaptimmune Ltd Engineered T cells

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CA2795695A1 (en) * 2010-04-09 2011-10-13 The University Of Tokyo Microrna-controlled recombinant vaccinia virus and use thereof
BR112013017096A2 (pt) 2011-01-04 2020-09-01 Jennerex Inc. composição e métodos de indução de resposta citotóxica dependente de complemento mediado por anticorpo específico de tumor em animal tendo tumor, de geração de anticorpos in vivo, de inibição do crescimento ou morte de célula de câncer, para tratar indivíduo com câncer, para adaptar de terapia de câncer para indivíduo com câncer e para identificar antígeno específico de tumor
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HUE060047T2 (hu) 2014-10-09 2023-01-28 Univ Yamaguchi CAR expressziós vektor és CAR-t expresszáló T-sejtek
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IL273689B1 (en) 2023-10-01
EP3695846A4 (en) 2021-06-30
US20200352997A1 (en) 2020-11-12
CN111163758A (zh) 2020-05-15
CL2020000950A1 (es) 2020-08-14
JP7232447B2 (ja) 2023-03-03
IL305898A (en) 2023-11-01
BR112020006746A2 (pt) 2020-10-06
RU2020113588A (ru) 2021-11-12
TW201927314A (zh) 2019-07-16
IL273689A (en) 2020-05-31
PH12020550241A1 (en) 2021-02-15
IL305898B1 (en) 2024-05-01
EP3695846B1 (en) 2023-11-29
EP4265634A2 (en) 2023-10-25
EP4265634A3 (en) 2024-01-24
SG11202003252TA (en) 2020-05-28
ES2970282T3 (es) 2024-05-27
JPWO2019073973A1 (ja) 2020-11-05
AU2018349889B2 (en) 2024-02-08
US11617765B2 (en) 2023-04-04
IL273689B2 (en) 2024-02-01
WO2019073973A1 (ja) 2019-04-18
RU2020113588A3 (es) 2021-12-13
AU2018349889A1 (en) 2020-04-02
CA3075886A1 (en) 2019-04-18
ZA202000986B (en) 2024-04-24
JP2023053087A (ja) 2023-04-12
EP3695846A1 (en) 2020-08-19
AU2024201332A1 (en) 2024-03-21
KR20200068661A (ko) 2020-06-15

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