MX2020002822A - Metodo de obtencion de una composicion que contiene una poblacion especifica de celulas mesenquimales de cordon umbilical y sus usos. - Google Patents

Metodo de obtencion de una composicion que contiene una poblacion especifica de celulas mesenquimales de cordon umbilical y sus usos.

Info

Publication number
MX2020002822A
MX2020002822A MX2020002822A MX2020002822A MX2020002822A MX 2020002822 A MX2020002822 A MX 2020002822A MX 2020002822 A MX2020002822 A MX 2020002822A MX 2020002822 A MX2020002822 A MX 2020002822A MX 2020002822 A MX2020002822 A MX 2020002822A
Authority
MX
Mexico
Prior art keywords
population
obtaining
composition containing
umbilical cord
cord mesenchymal
Prior art date
Application number
MX2020002822A
Other languages
English (en)
Inventor
Khoury Maroun
Fernando Figueroa
Francisco Espinoza
Jorge Bartolucci
Diego Castro
Paula Montoya
Paz González
Jimena Cuenca
Original Assignee
Cells For Cells S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cells For Cells S A filed Critical Cells For Cells S A
Publication of MX2020002822A publication Critical patent/MX2020002822A/es

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0668Mesenchymal stem cells from other natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)

Abstract

La presente invención proporciona un método para obtener una población específica de células mesenquimales de cordón umbilical. Una composición que contiene esta población de células específicas es útil para preparar un medicamento que sirve para terapias celulares, tales como problemas del flujo de eyección cardiaco de pacientes con una fracción de eyección disminuida. Al mismo tiempo, esta subpoblación es útil para preparar un medicamento que sirve para aliviar el dolor y recuperar la funcionalidad del desgaste en articulaciones; para tratar problemas respiratorios, tales como lesiones pulmonares, lesiones pulmonares agudas, tales como el síndrome de distrés respiratorio agudo y para tratar lesiones cutáneas, tales como heridas crónicas y úlceras.
MX2020002822A 2017-09-16 2018-09-16 Metodo de obtencion de una composicion que contiene una poblacion especifica de celulas mesenquimales de cordon umbilical y sus usos. MX2020002822A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2017002357A CL2017002357A1 (es) 2017-09-16 2017-09-16 Método de obtención de una composición que contiene una población específica de células mesenquimales de cordón umbilical y sus usos
PCT/CL2018/050087 WO2019051623A1 (es) 2017-09-16 2018-09-16 Método de obtención de una composición que contiene una población específica de células mesenquimales de cordón umbilical y sus usos

Publications (1)

Publication Number Publication Date
MX2020002822A true MX2020002822A (es) 2020-10-12

Family

ID=63046513

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020002822A MX2020002822A (es) 2017-09-16 2018-09-16 Metodo de obtencion de una composicion que contiene una poblacion especifica de celulas mesenquimales de cordon umbilical y sus usos.

Country Status (11)

Country Link
US (1) US20200297778A1 (es)
EP (1) EP3683305A4 (es)
JP (1) JP7218947B2 (es)
CN (1) CN111630156A (es)
BR (1) BR112020005017A2 (es)
CL (1) CL2017002357A1 (es)
CO (1) CO2020004383A2 (es)
EC (1) ECSP20022447A (es)
MX (1) MX2020002822A (es)
PE (1) PE20201347A1 (es)
WO (1) WO2019051623A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110101874A (zh) * 2018-10-27 2019-08-09 广州呼吸健康研究院 一种利用hgf转基因的干细胞治疗ards的方法
AU2021232614A1 (en) * 2020-03-05 2022-09-29 Mesoblast International Sàrl Method for treating inflammatory lung diseases using mesenchymal lineage precursor or stem cells
CN111840577B (zh) * 2020-05-09 2022-09-13 新乡医学院 一种提高ucmsc肺部输送效率的方法
CN112522193B (zh) * 2020-12-25 2023-03-21 博雅干细胞科技有限公司 无血清培养基在分离和传代脂肪间充质干细胞中的用途
CN114317421B (zh) * 2021-12-16 2024-05-03 北京科技大学 强化间充质干细胞促进血管生成的方法、组合物及应用
CN114159469A (zh) * 2021-12-20 2022-03-11 杭州易文赛生物技术有限公司 一种脐带间充质干细胞在制备修复海马神经元缺氧损伤的药物中的用途
CN116474000B (zh) * 2023-06-20 2023-09-19 北京中卫医正科技有限公司 脐带间充质干细胞制剂、制备方法及其在治疗膝骨关节炎中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005322133B2 (en) * 2004-12-23 2011-06-30 Ethicon Incorporated Treatment of Parkinson's disease and related disorders using postpartum derived cells
US20080050347A1 (en) * 2006-08-23 2008-02-28 Ichim Thomas E Stem cell therapy for cardiac valvular dysfunction
BR112012017463A2 (pt) * 2010-01-14 2015-09-15 Organogenesis Inc constructos de tecido de bioengenharia e métodos para sua produção e uso
US20140341863A1 (en) * 2011-11-01 2014-11-20 Neostem, Inc. Adult mesenchymal stem cell (msc) compositions and methods for preparing the same
IN2014MN01680A (es) * 2012-02-13 2015-07-03 Gamida Cell Ltd
WO2014052912A1 (en) * 2012-09-28 2014-04-03 Scripps Health Methods of differentiating stem cells into chondrocytes
CN103263440A (zh) * 2013-02-08 2013-08-28 周胜利 从胎盘、脐带中提、制同源性间充质干细胞注射剂的方法

Also Published As

Publication number Publication date
JP7218947B2 (ja) 2023-02-07
PE20201347A1 (es) 2020-11-30
US20200297778A1 (en) 2020-09-24
BR112020005017A2 (pt) 2020-09-15
EP3683305A4 (en) 2021-06-09
WO2019051623A1 (es) 2019-03-21
CN111630156A (zh) 2020-09-04
JP2020533011A (ja) 2020-11-19
EP3683305A1 (en) 2020-07-22
CL2017002357A1 (es) 2018-04-20
CO2020004383A2 (es) 2020-04-24
ECSP20022447A (es) 2020-09-30

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