MX2020001412A - Compuestos y métodos para tratar la hiperpotasemia. - Google Patents
Compuestos y métodos para tratar la hiperpotasemia.Info
- Publication number
- MX2020001412A MX2020001412A MX2020001412A MX2020001412A MX2020001412A MX 2020001412 A MX2020001412 A MX 2020001412A MX 2020001412 A MX2020001412 A MX 2020001412A MX 2020001412 A MX2020001412 A MX 2020001412A MX 2020001412 A MX2020001412 A MX 2020001412A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- treat
- hyperkolaemia
- methods
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 102000004277 11-beta-hydroxysteroid dehydrogenases Human genes 0.000 abstract 1
- 108090000874 11-beta-hydroxysteroid dehydrogenases Proteins 0.000 abstract 1
- 208000002682 Hyperkalemia Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B3/00—Simple or compound lenses
- G02B3/0006—Arrays
- G02B3/0037—Arrays characterized by the distribution or form of lenses
- G02B3/0056—Arrays characterized by the distribution or form of lenses arranged along two different directions in a plane, e.g. honeycomb arrangement of lenses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/02—Diffusing elements; Afocal elements
- G02B5/0205—Diffusing elements; Afocal elements characterised by the diffusing properties
- G02B5/021—Diffusing elements; Afocal elements characterised by the diffusing properties the diffusion taking place at the element's surface, e.g. by means of surface roughening or microprismatic structures
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/01—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour
- G02F1/13—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells
- G02F1/133—Constructional arrangements; Operation of liquid crystal cells; Circuit arrangements
- G02F1/1333—Constructional arrangements; Manufacturing methods
- G02F1/1335—Structural association of cells with optical devices, e.g. polarisers or reflectors
- G02F1/133524—Light-guides, e.g. fibre-optic bundles, louvered or jalousie light-guides
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/01—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour
- G02F1/13—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells
- G02F1/133—Constructional arrangements; Operation of liquid crystal cells; Circuit arrangements
- G02F1/1333—Constructional arrangements; Manufacturing methods
- G02F1/1335—Structural association of cells with optical devices, e.g. polarisers or reflectors
- G02F1/133526—Lenses, e.g. microlenses or Fresnel lenses
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B2207/00—Coding scheme for general features or characteristics of optical elements and systems of subclass G02B, but not including elements and systems which would be classified in G02B6/00 and subgroups
- G02B2207/123—Optical louvre elements, e.g. for directional light blocking
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nonlinear Science (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Mathematical Physics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762541095P | 2017-08-04 | 2017-08-04 | |
| PCT/US2018/045421 WO2019060051A1 (en) | 2017-08-04 | 2018-08-06 | GLYCYRRHETINIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERKALIEMIA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020001412A true MX2020001412A (es) | 2020-08-03 |
Family
ID=63364189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020001412A MX2020001412A (es) | 2017-08-04 | 2018-08-06 | Compuestos y métodos para tratar la hiperpotasemia. |
| MX2023015126A MX2023015126A (es) | 2017-08-04 | 2020-02-04 | Compuestos y metodos para tratar la hiperpotasemia. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023015126A MX2023015126A (es) | 2017-08-04 | 2020-02-04 | Compuestos y metodos para tratar la hiperpotasemia. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US11768319B2 (https=) |
| EP (2) | EP3661945B1 (https=) |
| JP (3) | JP7281446B2 (https=) |
| KR (2) | KR20200074085A (https=) |
| CN (2) | CN118440135A (https=) |
| AU (3) | AU2018335130B2 (https=) |
| BR (1) | BR112020002322A2 (https=) |
| CA (1) | CA3071992A1 (https=) |
| EA (1) | EA202090438A1 (https=) |
| IL (3) | IL318937A (https=) |
| MA (1) | MA49761A (https=) |
| MX (2) | MX2020001412A (https=) |
| PH (1) | PH12020500432A1 (https=) |
| SG (1) | SG11202000950TA (https=) |
| UA (1) | UA126584C2 (https=) |
| WO (1) | WO2019060051A1 (https=) |
| ZA (2) | ZA202001352B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20260004570A (ko) * | 2019-02-07 | 2026-01-08 | 알데릭스, 인코포레이티드 | 고칼륨혈증 치료에 사용하기 위한 글리시레틴산 유도체 |
| CN111018938B (zh) * | 2019-12-10 | 2021-05-25 | 中国人民解放军第二军医大学 | 一种五环三萜类甘草次酸衍生物及制备方法与应用 |
Family Cites Families (45)
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| DE2714880A1 (de) | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| US5519008A (en) * | 1992-09-10 | 1996-05-21 | Glycomed Incorporated | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) |
| DK0612723T3 (da) | 1993-02-20 | 1998-03-30 | Hoechst Ag | Substituerede benzoylguanidiner, fremgangsmåde til fremstilling, deres anvendelse som lægemiddel, som inhibitor af den cellulære Na+/H+-udbytning eller som diagnostikum samt lægemiddel med indhold deraf |
| IL109570A0 (en) | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE19518796A1 (de) | 1995-05-22 | 1996-11-28 | Hoechst Ag | Fluorphenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19548812A1 (de) | 1995-12-27 | 1997-07-03 | Hoechst Ag | Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikaments zur Atemstimulation |
| DE19633966A1 (de) | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| JP4166433B2 (ja) * | 1997-09-11 | 2008-10-15 | 第一製薬株式会社 | ホルモン依存性疾患治療剤 |
| DE19945302A1 (de) | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenylderivate als NHE-3-Inhibitoren |
| US6887870B1 (en) | 1999-10-12 | 2005-05-03 | Bristol-Myers Squibb Company | Heterocyclic sodium/proton exchange inhibitors and method |
| DE10015248A1 (de) | 2000-03-28 | 2001-10-04 | Merck Patent Gmbh | Bisamidino-Verbindungen als NHE-3 Inhibitoren |
| DE10019062A1 (de) | 2000-04-18 | 2001-10-25 | Merck Patent Gmbh | 2-Guanidino-4-aryl-chinazoline als NHE-3 Inhibitoren |
| DE10043667A1 (de) | 2000-09-05 | 2002-03-14 | Merck Patent Gmbh | 2-Guanidino-4-aryl-chinazoline |
| DE10046993A1 (de) | 2000-09-22 | 2002-04-11 | Aventis Pharma Gmbh | Substituierte Zimtsäureguanidide, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament |
| DE10063294A1 (de) | 2000-12-19 | 2002-07-04 | Aventis Pharma Gmbh | Substituierte Heterocyclo-Norbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US6736705B2 (en) | 2001-04-27 | 2004-05-18 | Hitachi Global Storage Technologies | Polishing process for glass or ceramic disks used in disk drive data storage devices |
| US6911453B2 (en) | 2001-12-05 | 2005-06-28 | Aventis Pharma Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them |
| DE10161767A1 (de) | 2001-12-15 | 2003-06-26 | Merck Patent Gmbh | 2-Guanidino-4-heterocyclyl-chinazoline |
| US6703405B2 (en) | 2001-12-22 | 2004-03-09 | Aventis Pharma Deutschland Gmbh | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them |
| DE10163992A1 (de) | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | 4-Aryl-chinazoline |
| GB0224830D0 (en) * | 2002-10-24 | 2002-12-04 | Sterix Ltd | Compound |
| CN1254051C (zh) | 2002-10-25 | 2006-04-26 | 华为技术有限公司 | 城域网传输设备中用户数据业务子速率传送方法 |
| US6923466B2 (en) | 2002-12-17 | 2005-08-02 | James Tsai | Collapsible handcart capable of extending the area of carrier by operating handle |
| US20050054705A1 (en) | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
| WO2004113396A1 (ja) | 2003-06-25 | 2004-12-29 | Cmet Inc. | 安定性の向上した活性エネルギー線硬化性の光学的立体造形用樹脂組成物 |
| WO2005020612A1 (en) | 2003-08-20 | 2005-03-03 | Musky Communications (Proprietary) Limited | Telephonic communication |
| SI1663185T1 (sl) * | 2003-09-22 | 2009-04-30 | Onepharm Res & Dev Gmbh | Preprečevanje in zdravljenje z vnetjem inducirane in/ali imunsko posredovane izgube kosti |
| WO2005054705A2 (en) | 2003-11-26 | 2005-06-16 | Brian Judd | Apparatus for dampening impact vibration in manual tools |
| US20050244367A1 (en) | 2004-05-03 | 2005-11-03 | Ilypsa, Inc. | Phospholipase inhibitors localized in the gastrointestinal lumen |
| KR20070038042A (ko) | 2004-05-14 | 2007-04-09 | 파세코 코퍼레이션 | 컨테이너 핸들러들을 위한 상황 보고 디바이스들을 만드는장치 및 방법 |
| DE102004046492A1 (de) | 2004-09-23 | 2006-03-30 | Sanofi-Aventis Deutschland Gmbh | Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| DE102004054847A1 (de) | 2004-11-13 | 2006-05-24 | Sanofi-Aventis Deutschland Gmbh | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE102005044817A1 (de) | 2005-09-20 | 2007-03-22 | Sanofi-Aventis Deutschland Gmbh | Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
| MX2008005661A (es) | 2005-11-03 | 2008-12-15 | Ilypsa Inc | Inhibidores de fosfolipasa, que incluyen inhibidores de fosfolipasa multivalente, y uso de los mismos, que incluyen como inhibidores de fosfolipasa localizadas en el lumen. |
| US7666898B2 (en) | 2005-11-03 | 2010-02-23 | Ilypsa, Inc. | Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors |
| GB0604899D0 (en) | 2006-03-10 | 2006-04-19 | York Pharma Plc | Derivatives of 18-glycyrrhetinic acid |
| GB0610009D0 (en) | 2006-05-19 | 2006-06-28 | Health Prot Agency | Culture medium |
| GB2438389A (en) | 2006-05-23 | 2007-11-28 | Gkn Aerospace Transparency Sys | Heating system for leading edge of aircraft |
| SI2384318T1 (en) | 2008-12-31 | 2018-03-30 | Ardelyx, Inc. | MEASURES AND PROCEDURES FOR THE INHIBITION OF ANTIPORT INHIBITED BY NHE IN THE TREATMENT OF DISEASES RELATED TO STRENGTH OF FLAMMABILITY OR TRADEMARITY WITH SOLO, AND THE EMISSION OF GASTROINTESTINAL TREATMENT |
| EP2228380A1 (en) | 2009-03-13 | 2010-09-15 | onepharm Research & Development GmbH | Novel triterpene derivatives |
| KR101886467B1 (ko) | 2011-01-31 | 2018-08-07 | 비브 헬스케어 유케이 (넘버4) 리미티드 | Hiv 성숙 억제 활성을 갖는 c-17 및 c-3 변형 트리테르페노이드 |
| US9120839B2 (en) | 2012-08-14 | 2015-09-01 | Nexoligo Co., Ltd. | Ursolic acid derivative and method for preparing same |
| MX366293B (es) | 2012-08-21 | 2019-07-04 | Ardelyx Inc | Compuestos y metodos para inhibir al antipuerto mediado por nhe en el tratamiento de trastornos asociados con la retencion de fluidos o la sobrecarga de sal y trastornos del tracto gastrointestinal. |
| BR112015003516A2 (pt) | 2012-08-21 | 2017-07-04 | Ardelyx Inc | compostos e métodos para inibição de antiporte mediado por nhe no tratamento de transtornos associados à retenção de fluido ou sobrecarga de sal e transtornos do trato gastrintestinal |
| TW201628631A (zh) | 2014-12-23 | 2016-08-16 | 亞德利克斯公司 | 用於治療高血鉀症之組合物及方法 |
-
2018
- 2018-08-06 CN CN202410298024.3A patent/CN118440135A/zh active Pending
- 2018-08-06 SG SG11202000950TA patent/SG11202000950TA/en unknown
- 2018-08-06 IL IL318937A patent/IL318937A/en unknown
- 2018-08-06 US US16/636,596 patent/US11768319B2/en active Active
- 2018-08-06 KR KR1020207006241A patent/KR20200074085A/ko not_active Ceased
- 2018-08-06 WO PCT/US2018/045421 patent/WO2019060051A1/en not_active Ceased
- 2018-08-06 AU AU2018335130A patent/AU2018335130B2/en active Active
- 2018-08-06 CN CN201880064384.XA patent/CN111386279A/zh active Pending
- 2018-08-06 JP JP2020506272A patent/JP7281446B2/ja active Active
- 2018-08-06 MX MX2020001412A patent/MX2020001412A/es unknown
- 2018-08-06 KR KR1020247031867A patent/KR20240144491A/ko active Pending
- 2018-08-06 IL IL306058A patent/IL306058A/en unknown
- 2018-08-06 EP EP18759491.6A patent/EP3661945B1/en active Active
- 2018-08-06 EA EA202090438A patent/EA202090438A1/ru unknown
- 2018-08-06 MA MA049761A patent/MA49761A/fr unknown
- 2018-08-06 BR BR112020002322-1A patent/BR112020002322A2/pt not_active Application Discontinuation
- 2018-08-06 CA CA3071992A patent/CA3071992A1/en active Pending
- 2018-08-06 EP EP24159204.7A patent/EP4397366A3/en active Pending
- 2018-08-06 IL IL272443A patent/IL272443B2/en unknown
- 2018-08-06 UA UAA202001392A patent/UA126584C2/uk unknown
-
2020
- 2020-02-04 MX MX2023015126A patent/MX2023015126A/es unknown
- 2020-03-03 ZA ZA2020/01352A patent/ZA202001352B/en unknown
- 2020-03-03 PH PH12020500432A patent/PH12020500432A1/en unknown
-
2021
- 2021-04-29 ZA ZA2021/02866A patent/ZA202102866B/en unknown
-
2023
- 2023-01-24 US US18/101,009 patent/US20230273354A1/en not_active Abandoned
- 2023-02-27 JP JP2023028553A patent/JP2023054360A/ja not_active Withdrawn
- 2023-05-15 AU AU2023203009A patent/AU2023203009A1/en not_active Abandoned
-
2024
- 2024-09-03 US US18/823,388 patent/US20250067907A1/en active Pending
- 2024-11-29 JP JP2024207992A patent/JP2025029026A/ja active Pending
-
2025
- 2025-02-27 AU AU2025201400A patent/AU2025201400A1/en active Pending
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