MX2019013723A - Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer. - Google Patents

Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.

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Publication number
MX2019013723A
MX2019013723A MX2019013723A MX2019013723A MX2019013723A MX 2019013723 A MX2019013723 A MX 2019013723A MX 2019013723 A MX2019013723 A MX 2019013723A MX 2019013723 A MX2019013723 A MX 2019013723A MX 2019013723 A MX2019013723 A MX 2019013723A
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Mexico
Prior art keywords
cancer
combination therapy
treatment
antibodies against
therapy involving
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MX2019013723A
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English (en)
Inventor
Rita Mitnacht-Kraus
Stefan Denis Jacobs
Magdalena Jadwiga Utsch
Cornelia Adriana Maria Heinz
Christiane Regina Stadler
Özlem Türeci
Ugur Sahin
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Astellas Pharma Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48483023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019013723(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of MX2019013723A publication Critical patent/MX2019013723A/es

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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046Stomach, Intestines
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

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Abstract

La presente invención proporciona una terapia de combinación para tratar y/o prevenir efectivamente enfermedades asociadas con células que expresan CLDN18.2, que incluyen enfermedades de cáncer tales como cáncer gástrico, cáncer esofágico, cáncer pancreático,cáncer pulmonar, cáncer de ovarios, cáncer de colon, cáncer hepático, cáncer de cabezacuello, y cáncer de la vesícula biliar y metástasis de los mismos.
MX2019013723A 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer. MX2019013723A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/002210 WO2013174403A1 (en) 2012-05-23 2012-05-23 Combination therapy involving antibodies against claudin 18.2 for treatment of cancer

Publications (1)

Publication Number Publication Date
MX2019013723A true MX2019013723A (es) 2020-07-20

Family

ID=48483023

Family Applications (5)

Application Number Title Priority Date Filing Date
MX2014014216A MX2014014216A (es) 2012-05-23 2013-05-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2019013723A MX2019013723A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2020011780A MX2020011780A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2020011771A MX2020011771A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2020011782A MX2020011782A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.

Family Applications Before (1)

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MX2014014216A MX2014014216A (es) 2012-05-23 2013-05-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.

Family Applications After (3)

Application Number Title Priority Date Filing Date
MX2020011780A MX2020011780A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2020011771A MX2020011771A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.
MX2020011782A MX2020011782A (es) 2012-05-23 2014-11-21 Terapia de combinacion que involucra anticuerpos contra claudina 18.2 para tratamiento de cancer.

Country Status (26)

Country Link
US (2) US20150132253A1 (es)
JP (2) JP6203831B2 (es)
KR (3) KR20240010757A (es)
CN (2) CN104379166B (es)
AR (2) AR091130A1 (es)
AU (2) AU2013265638B2 (es)
BR (1) BR112014028948B8 (es)
CA (1) CA2874032A1 (es)
DK (2) DK2852408T3 (es)
ES (2) ES2637416T3 (es)
FI (1) FI3791896T3 (es)
HK (1) HK1208152A1 (es)
HR (2) HRP20240169T1 (es)
HU (2) HUE036000T2 (es)
IL (2) IL235607A0 (es)
LT (3) LT3254695T (es)
MX (5) MX2014014216A (es)
NZ (2) NZ701585A (es)
PL (1) PL3791896T3 (es)
PT (3) PT3791896T (es)
RS (2) RS65179B1 (es)
RU (1) RU2665321C2 (es)
SG (2) SG11201406977TA (es)
SI (2) SI3254695T1 (es)
UA (1) UA118013C2 (es)
WO (2) WO2013174403A1 (es)

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