MX2019012964A - Sistema de perfusion intracorporal. - Google Patents

Sistema de perfusion intracorporal.

Info

Publication number
MX2019012964A
MX2019012964A MX2019012964A MX2019012964A MX2019012964A MX 2019012964 A MX2019012964 A MX 2019012964A MX 2019012964 A MX2019012964 A MX 2019012964A MX 2019012964 A MX2019012964 A MX 2019012964A MX 2019012964 A MX2019012964 A MX 2019012964A
Authority
MX
Mexico
Prior art keywords
fluid
transmission line
flow restriction
restriction element
microchannel
Prior art date
Application number
MX2019012964A
Other languages
English (en)
Inventor
Andretta Carlo
Original Assignee
Seraip Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seraip Ag filed Critical Seraip Ag
Publication of MX2019012964A publication Critical patent/MX2019012964A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3655—Arterio-venous shunts or fistulae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A61M1/3673—Anticoagulant coating, e.g. Heparin coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
    • A61M2205/106—General characteristics of the apparatus with powered movement mechanisms reciprocating

Abstract

Un dispositivo (2) de perfusión implantable comprende una línea (4) de transmisión tubular con un extremo (6) de admisión, un extremo (8) de descarga y un elemento (10) de restricción de flujo situado entre los mismos, de modo que una sección (12) de admisión de la línea de transmisión está definida entre el extremo de admisión y el elemento de restricción de flujo y de modo que una sección (14) de descarga de la línea de transmisión está definida entre el elemento de restricción de flujo y el extremo de descarga. Asimismo, el dispositivo: comprende una cámara (16) de perfusión que contiene una carga de células biológicamente activas y está provista de una entrada (18) de fluido, una salida (20) de fluido y un volumen de una cámara (22) formada entre las mismas. La entrada de fluido comprende al menos un primer microcanal plaquetario (24) y la salida de fluido comprende al menos un segundo microcanal plaquetario (26), comprendiendo cada uno de los microcanales plaquetarios al menos una matriz de microcanales(28) que definen un paso de fluido entre las respectivas caras plaquetarias externa e interna, teniendo los microcanales plaquetarios al menos una abertura de 0,2 a 10 µm. La entrada (18) de fluido de la cámara de perfusión está en comunicación fluida con la sección (12) de admisión de la línea de transmisión; y el elemento (10) de restricción de flujo está configurado para establecer un exceso de presión predeterminado en la sección (12) de admisión con respecto a la sección (14) de descarga.
MX2019012964A 2017-05-02 2018-05-02 Sistema de perfusion intracorporal. MX2019012964A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17169158.7A EP3398558A1 (en) 2017-05-02 2017-05-02 In body perfusion system
PCT/EP2018/061127 WO2018202671A1 (en) 2017-05-02 2018-05-02 In-body perfusion system

Publications (1)

Publication Number Publication Date
MX2019012964A true MX2019012964A (es) 2019-12-16

Family

ID=58668776

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012964A MX2019012964A (es) 2017-05-02 2018-05-02 Sistema de perfusion intracorporal.

Country Status (16)

Country Link
US (1) US11529463B2 (es)
EP (2) EP3398558A1 (es)
JP (1) JP7049688B2 (es)
KR (1) KR102612124B1 (es)
CN (1) CN110636815B (es)
AU (1) AU2018263784B2 (es)
BR (1) BR112019023189A2 (es)
CA (1) CA3054766A1 (es)
DK (1) DK3618761T3 (es)
ES (1) ES2955885T3 (es)
MX (1) MX2019012964A (es)
RU (1) RU2019134379A (es)
SA (1) SA519410153B1 (es)
SG (1) SG11201908201QA (es)
WO (1) WO2018202671A1 (es)
ZA (1) ZA201905803B (es)

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002661A (en) * 1989-08-25 1991-03-26 W. R. Grace & Co.-Conn. Artificial pancreatic perfusion device
DE4001319A1 (de) 1990-01-18 1991-07-25 Jakob Dr Bodziony Ein implantierbares und biologisch aktive substanzen sezernierendes bioartifizielles organ
US5425764A (en) * 1992-07-30 1995-06-20 The University Of Toledo Bioartificial pancreas
US5387237A (en) * 1992-07-30 1995-02-07 The University Of Toledo Bioartificial pancreas
US6472200B1 (en) * 1999-07-23 2002-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Device and method for performing a biological modification of a fluid
US5741334A (en) 1995-06-07 1998-04-21 Circe Biomedical, Inc. Artificial pancreatic perfusion device
AU6501296A (en) * 1995-07-21 1997-02-18 General Hospital Corporation, The Method and apparatus of enhancing the delivery of a pharmaceutical formulation
EP1203075B1 (en) 1999-06-21 2007-09-12 The General Hospital Corporation Cell culture systems and methods for organ assist devices
US20020151055A1 (en) 1999-11-02 2002-10-17 Stegemann Jan Philip Novel artificial pancreas
US7029838B2 (en) * 2001-03-30 2006-04-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized contructs for implantation to provide blood perfusion
JP2003190259A (ja) 2001-12-28 2003-07-08 Hisako Ogawara 人工臓器用チャンバー
JP4195354B2 (ja) * 2003-02-26 2008-12-10 クラレメディカル株式会社 バイオ人工膵臓用モジュール及びバイオ人工膵臓
US8460243B2 (en) 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
CN101022769A (zh) * 2004-07-29 2007-08-22 迈阿密大学 用于细胞治疗的杂交装置
KR101509827B1 (ko) 2007-03-19 2015-04-06 인슐린 메디컬 엘티디 약물 전달 방법 및 장치
CN107988072B (zh) * 2008-07-16 2022-11-29 儿童医疗中心有限公司 具有微通道的器官模仿装置及其使用和制造方法
CA2748267A1 (en) * 2008-12-26 2010-07-01 Shinichi Matsumoto Large scale pancreatic islet purification
ES2827703T3 (es) 2009-01-08 2021-05-24 Bio Dg Inc Dispositivos médicos implantables que comprenden aleaciones biodegradables
EP2395946B1 (de) * 2009-02-11 2016-08-24 CeramTec GmbH Keramischer pfanneneinsatz mit invers-konischem führungszapfen
CN101926788B (zh) * 2009-06-18 2012-12-19 刘力 心脑血管及眼科药物及其制备和用途
CN102240417B (zh) * 2011-07-11 2013-12-18 薛磊 一种双层滤膜的血液过滤回输袋
US9931121B2 (en) * 2011-10-17 2018-04-03 University Of Utah Research Foundation Methods and devices for connecting nerves
WO2013098823A2 (en) 2011-12-28 2013-07-04 Clil Medical Ltd. System and method for blood filtering and/or treatment
ITUD20120028A1 (it) * 2012-02-21 2013-08-22 Sedicidodici S R L Camera di perfusione, relativa apparecchiatura utilizzante tale camera di perfusione e procedimento per l'analisi della patologia trombotico-ischemica ed emorragica
CN102600521A (zh) * 2012-03-19 2012-07-25 王天欣 一种清除血液中病原体的装置和方法
CN102614556B (zh) * 2012-04-19 2014-11-05 南京红十字血液中心 一种高效滤除白细胞的组合滤膜及其制法和白细胞过滤器
GB201212771D0 (en) * 2012-07-18 2012-08-29 Northwick Park Inst For Medcal Res Ltd Implant and method for producing an implant
WO2014109898A1 (en) 2013-01-14 2014-07-17 The Regents Of University Of California Model-based personalization scheme of an artificial pancreas for type i diabetes applications
CN103054903A (zh) * 2013-01-15 2013-04-24 西安交通大学医学院第一附属医院 成人睾丸支持细胞-胰岛复合物及其制备方法
CN103396986B (zh) * 2013-08-15 2015-04-22 华北制药金坦生物技术股份有限公司 一种动物细胞灌注培养方法及其专用装置和应用
US10231817B2 (en) * 2013-09-24 2019-03-19 Giner Life Sciences, Inc. System for gas treatment of a cell implant
CN104622480B (zh) * 2013-11-12 2017-12-05 上海移宇科技股份有限公司 单针集成型人工胰腺
RU2544256C1 (ru) 2013-11-15 2015-03-20 Александр Михайлович Деревягин Устройство для измерения скорости потока текучей среды
KR101571782B1 (ko) 2014-01-22 2015-11-25 연세대학교 산학협력단 정맥 삽입형 인공 췌장
PL3427814T3 (pl) 2014-02-06 2023-01-02 Gambro Lundia Ab Hemodializator do oczyszczania krwi
CN204779609U (zh) * 2015-02-16 2015-11-18 昆明市第一人民医院 体外循环灌流构建组织工程肝的生物反应器

Also Published As

Publication number Publication date
US11529463B2 (en) 2022-12-20
CN110636815A (zh) 2019-12-31
EP3618761B1 (en) 2023-06-28
KR20200002852A (ko) 2020-01-08
CN110636815B (zh) 2022-03-08
RU2019134379A (ru) 2021-06-02
ES2955885T3 (es) 2023-12-07
ZA201905803B (en) 2021-02-24
EP3618761A1 (en) 2020-03-11
AU2018263784A1 (en) 2019-09-26
AU2018263784B2 (en) 2023-11-30
JP2020518308A (ja) 2020-06-25
SA519410153B1 (ar) 2023-02-21
RU2019134379A3 (es) 2021-06-09
CA3054766A1 (en) 2018-11-08
EP3398558A1 (en) 2018-11-07
US20200069874A1 (en) 2020-03-05
SG11201908201QA (en) 2019-10-30
BR112019023189A2 (pt) 2020-05-19
DK3618761T3 (en) 2023-07-31
KR102612124B1 (ko) 2023-12-08
WO2018202671A1 (en) 2018-11-08
JP7049688B2 (ja) 2022-04-07

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