MX2019006685A - Combinacion terapeutica para el tratamiento de cancer. - Google Patents

Combinacion terapeutica para el tratamiento de cancer.

Info

Publication number
MX2019006685A
MX2019006685A MX2019006685A MX2019006685A MX2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A MX 2019006685 A MX2019006685 A MX 2019006685A
Authority
MX
Mexico
Prior art keywords
cancer
treatment
therapeutic combination
combinations
nerium
Prior art date
Application number
MX2019006685A
Other languages
English (en)
Inventor
R Knocke Dennis
B Nester Joseph
Papasotiriou Ioannis
Original Assignee
Nerium Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerium Biotechnology Inc filed Critical Nerium Biotechnology Inc
Publication of MX2019006685A publication Critical patent/MX2019006685A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Esta invención se relaciona a combinaciones terapéuticas que comprenden un agente antineoplástico a base de platino, como cisplatino y un extracto de especies del género Nerium oleander, así como también métodos de uso de las combinaciones para tratar sujetos, incluyendo humanos, que sufren de ciertos cánceres, como cáncer de próstata, melanoma, cáncer pancreático, cáncer pulmonar, cáncer de mama o cáncer colorrectal.
MX2019006685A 2011-10-20 2014-04-14 Combinacion terapeutica para el tratamiento de cancer. MX2019006685A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161549386P 2011-10-20 2011-10-20

Publications (1)

Publication Number Publication Date
MX2019006685A true MX2019006685A (es) 2019-08-21

Family

ID=48141445

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014004527A MX365635B (es) 2011-10-20 2012-10-20 Combinacion terapeutica para el tratamiento de cancer.
MX2019006685A MX2019006685A (es) 2011-10-20 2014-04-14 Combinacion terapeutica para el tratamiento de cancer.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2014004527A MX365635B (es) 2011-10-20 2012-10-20 Combinacion terapeutica para el tratamiento de cancer.

Country Status (13)

Country Link
US (2) US20130209579A1 (es)
EP (2) EP2768498B1 (es)
JP (1) JP6255346B2 (es)
CN (2) CN104093405A (es)
AU (3) AU2012325819B2 (es)
BR (1) BR112014009421A2 (es)
CA (1) CA2852274C (es)
GT (1) GT201400071A (es)
IL (2) IL231987B (es)
IN (1) IN2014KN00796A (es)
MX (2) MX365635B (es)
RU (2) RU2017136415A (es)
WO (1) WO2013059753A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions
EP3285758B1 (en) * 2015-04-22 2020-04-08 Syn-Nat Products Enterprise LLC Co-crystal composition and its pharmaceutical use
EA037248B1 (ru) * 2015-10-05 2021-02-26 НУКАНА ПиЭлСи Применение гемцитабин[фенил-бензокси-l-аланинил]фосфата в комбинации с карбоплатином

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84857B (pt) 1986-05-13 1990-02-08 Huseyin Ziya Ozel Processo para a preparacao de extractos de plantas da especie nerium e de composicoes farmaceuticas que os contem
CA2354037A1 (en) 1998-09-24 2000-03-30 Ozelle Pharmaceuticals, Inc. Extract of nerium species, pharmaceutical composition thereof and methods for preparation thereof
US7407675B2 (en) * 2002-12-27 2008-08-05 The Trustees Of Columbia University In The City Of New York Anti-neoplastic compositions comprising extracts of black cohosh
US20060205679A1 (en) * 2004-10-22 2006-09-14 Azaya Therapeutics, Inc. Topical and oral formulations of cardiac glycosides for treating skin diseases
US7402325B2 (en) 2005-07-28 2008-07-22 Phoenix Biotechnology, Inc. Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
EP1803461A1 (en) * 2005-12-27 2007-07-04 Heinz-Herbert Fiebig Therapeutic use of an extract from the leaves of Nerium oleander
PL2173337T3 (pl) 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions

Also Published As

Publication number Publication date
US20130209579A1 (en) 2013-08-15
IN2014KN00796A (es) 2015-10-02
CA2852274A1 (en) 2013-04-25
NZ623550A (en) 2016-06-24
MX2014004527A (es) 2014-09-15
AU2017254875A1 (en) 2017-11-23
GT201400071A (es) 2015-09-17
US20190343908A1 (en) 2019-11-14
CN104093405A (zh) 2014-10-08
AU2019203577A1 (en) 2019-06-13
RU2017136415A (ru) 2019-02-08
RU2017136415A3 (es) 2021-02-08
EP2768498B1 (en) 2020-03-04
MX365635B (es) 2019-06-10
IL231987A0 (en) 2014-05-28
JP6255346B2 (ja) 2017-12-27
EP3711754A1 (en) 2020-09-23
WO2013059753A1 (en) 2013-04-25
IL231987B (en) 2020-07-30
CA2852274C (en) 2019-08-06
EP2768498A1 (en) 2014-08-27
EP2768498A4 (en) 2015-06-17
BR112014009421A2 (pt) 2017-04-18
AU2012325819A1 (en) 2014-04-24
IL275636A (en) 2020-08-31
CN110269940A (zh) 2019-09-24
AU2012325819B2 (en) 2017-08-03
RU2014120179A (ru) 2015-11-27
JP2014530878A (ja) 2014-11-20

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