IN2014KN00796A - - Google Patents

Info

Publication number
IN2014KN00796A
IN2014KN00796A IN796KON2014A IN2014KN00796A IN 2014KN00796 A IN2014KN00796 A IN 2014KN00796A IN 796KON2014 A IN796KON2014 A IN 796KON2014A IN 2014KN00796 A IN2014KN00796 A IN 2014KN00796A
Authority
IN
India
Prior art keywords
cancer
combinations
oleanderthis
neriumnerium
cisplatin
Prior art date
Application number
Inventor
Dennis R Knocke
Joseph B Nester
Ioannis Papasotiriou
Original Assignee
Nerium Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerium Biotechnology Inc filed Critical Nerium Biotechnology Inc
Publication of IN2014KN00796A publication Critical patent/IN2014KN00796A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

NeriumNerium oleanderThis invention relates to therapeutic combinations comprising a platinum based antineoplastic agent such as cisplatin and an extract from a species of the genus such as as well as methods of using such combinations to treat subjects including humans suffering from certain cancers such as prostate cancer melanoma pancreatic cancer lung cancer breast cancer or colorectal cancer.
IN796KON2014 2011-10-20 2012-10-20 IN2014KN00796A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161549386P 2011-10-20 2011-10-20
PCT/US2012/061226 WO2013059753A1 (en) 2011-10-20 2012-10-20 Therapeutic combination for the treatment of cancer

Publications (1)

Publication Number Publication Date
IN2014KN00796A true IN2014KN00796A (en) 2015-10-02

Family

ID=48141445

Family Applications (1)

Application Number Title Priority Date Filing Date
IN796KON2014 IN2014KN00796A (en) 2011-10-20 2012-10-20

Country Status (13)

Country Link
US (2) US20130209579A1 (en)
EP (2) EP2768498B1 (en)
JP (1) JP6255346B2 (en)
CN (2) CN110269940A (en)
AU (3) AU2012325819B2 (en)
BR (1) BR112014009421A2 (en)
CA (1) CA2852274C (en)
GT (1) GT201400071A (en)
IL (2) IL231987B (en)
IN (1) IN2014KN00796A (en)
MX (2) MX365635B (en)
RU (2) RU2017136415A (en)
WO (1) WO2013059753A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions
AU2016250616B2 (en) * 2015-04-22 2021-01-21 Syn-Nat Products Enterprise LLC Co-crystal composition and its pharmaceutical use
JP7038653B2 (en) * 2015-10-05 2022-03-18 ニューカナ パブリック リミテッド カンパニー Combination therapy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI872106A (en) 1986-05-13 1987-11-14 Huseyin Ziya Ozel EXTRAKT AV NERIUM-ARTER, FOERFARANDE FOER FRAMSTAELLNING AV DEM OCH DERAS ANVAENDNING.
JP2002526452A (en) 1998-09-24 2002-08-20 オゼル・ファーマスーティカルズ・インコーポレイテッド Oleander extract, its pharmaceutical composition and its preparation method
US7407675B2 (en) * 2002-12-27 2008-08-05 The Trustees Of Columbia University In The City Of New York Anti-neoplastic compositions comprising extracts of black cohosh
US20060205679A1 (en) * 2004-10-22 2006-09-14 Azaya Therapeutics, Inc. Topical and oral formulations of cardiac glycosides for treating skin diseases
US7402325B2 (en) 2005-07-28 2008-07-22 Phoenix Biotechnology, Inc. Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
EP1803461A1 (en) 2005-12-27 2007-07-04 Heinz-Herbert Fiebig Therapeutic use of an extract from the leaves of Nerium oleander
JP5385274B2 (en) 2007-08-06 2014-01-08 オハイオ ユニバーシティー Phosphaplatin and its use in the treatment of cancer resistant to cisplatin and carboplatin
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions

Also Published As

Publication number Publication date
US20130209579A1 (en) 2013-08-15
MX2014004527A (en) 2014-09-15
IL275636A (en) 2020-08-31
AU2019203577A1 (en) 2019-06-13
IL231987B (en) 2020-07-30
EP2768498A1 (en) 2014-08-27
AU2012325819A1 (en) 2014-04-24
AU2017254875A1 (en) 2017-11-23
EP2768498B1 (en) 2020-03-04
BR112014009421A2 (en) 2017-04-18
RU2017136415A3 (en) 2021-02-08
AU2012325819B2 (en) 2017-08-03
CA2852274C (en) 2019-08-06
WO2013059753A1 (en) 2013-04-25
CN110269940A (en) 2019-09-24
JP6255346B2 (en) 2017-12-27
NZ623550A (en) 2016-06-24
US20190343908A1 (en) 2019-11-14
IL231987A0 (en) 2014-05-28
JP2014530878A (en) 2014-11-20
CN104093405A (en) 2014-10-08
GT201400071A (en) 2015-09-17
EP2768498A4 (en) 2015-06-17
MX2019006685A (en) 2019-08-21
MX365635B (en) 2019-06-10
RU2017136415A (en) 2019-02-08
CA2852274A1 (en) 2013-04-25
RU2014120179A (en) 2015-11-27
EP3711754A1 (en) 2020-09-23

Similar Documents

Publication Publication Date Title
PH12015501744B1 (en) Therapeutic and diagnostic target for cancer comprising dll3 binding reagents
MX360404B (en) Compounds for inhibiting cell proliferation in egfr-driven cancers.
SA515360657B1 (en) Histone demethylase inhibitors
MX2016002051A (en) Methods and kits for the molecular subtyping of tumors.
MX2013002084A (en) Biomarkers and methods of treatment.
MX366804B (en) R-spondin translocations and methods using the same.
UA109271C2 (en) Combination of phytocannabinoids and temosolamide for treating glioma
MX2015007185A (en) Use of eribulin in the treatment of breast cancer.
MX2014009751A (en) Antibodies to integrin avvb6 and use of same to treat cancer.
MX2016004678A (en) Methods and compositions for treating cancer.
WO2012122295A3 (en) Treatment for pancreatic adenocarcinoma and other cancers of epithelial origin
MA33973B1 (en) Ways to treat cancer using notch antagonists
MX336761B (en) Compounds for treatment of cancer.
MX2019006331A (en) Methods of treating cancer using anti-pd-l1 antibodies and antiandrogens.
EA201370071A1 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF LUNG CANCER
MX2014000199A (en) Combination therapy.
MX2013015340A (en) Compositions and methods for the treatment of cancer.
CR20110479A (en) PHARMACEUTICAL COMBINATIONS UNDERSTANDING RDEA 119 / BAY 869766 FOR THE TREATMENT OF SPECIFIC CANCERS
PH12019500135A1 (en) Methods of treating prostate cancer
MX2016010137A (en) Functionalised benzopyran compounds and use thereof.
FR2945210B1 (en) ANTITUMOR COMBINATION COMPRISING AVE8062 AND SORAFENIB
PH12015502757A1 (en) Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
WO2013188750A3 (en) Substituted macrocyclic compounds having proteasome inhibitory activity
WO2013081645A3 (en) Erbb3 mutations in cancer
IN2014KN00796A (en)