MX2019004499A - Sistemas de replicón de virus recombinante y usos de estos. - Google Patents
Sistemas de replicón de virus recombinante y usos de estos.Info
- Publication number
- MX2019004499A MX2019004499A MX2019004499A MX2019004499A MX2019004499A MX 2019004499 A MX2019004499 A MX 2019004499A MX 2019004499 A MX2019004499 A MX 2019004499A MX 2019004499 A MX2019004499 A MX 2019004499A MX 2019004499 A MX2019004499 A MX 2019004499A
- Authority
- MX
- Mexico
- Prior art keywords
- recombinant virus
- interest
- virus replicon
- modified
- replicon systems
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662409228P | 2016-10-17 | 2016-10-17 | |
| PCT/US2017/054928 WO2018075235A1 (en) | 2016-10-17 | 2017-10-03 | Recombinant virus replicon systems and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019004499A true MX2019004499A (es) | 2019-11-18 |
Family
ID=60153459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019004499A MX2019004499A (es) | 2016-10-17 | 2017-10-03 | Sistemas de replicón de virus recombinante y usos de estos. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11364310B2 (OSRAM) |
| EP (1) | EP3526332B1 (OSRAM) |
| JP (2) | JP7382230B2 (OSRAM) |
| KR (1) | KR102718353B1 (OSRAM) |
| CN (1) | CN110073002B (OSRAM) |
| AU (1) | AU2017347725B2 (OSRAM) |
| BR (1) | BR112019007433A2 (OSRAM) |
| ES (1) | ES2993107T3 (OSRAM) |
| MX (1) | MX2019004499A (OSRAM) |
| WO (1) | WO2018075235A1 (OSRAM) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10538786B2 (en) | 2016-04-13 | 2020-01-21 | Janssen Pharmaceuticals, Inc. | Recombinant arterivirus replicon systems and uses thereof |
| MX2019004499A (es) | 2016-10-17 | 2019-11-18 | Janssen Pharmaceuticals Inc Star | Sistemas de replicón de virus recombinante y usos de estos. |
| AU2017372731B2 (en) | 2016-12-05 | 2024-05-23 | Janssen Pharmaceuticals, Inc. | Compositions and methods for enhancing gene expression |
| US11020476B2 (en) | 2017-12-19 | 2021-06-01 | Janssen Sciences Ireland Unlimited Company | Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV) |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| CA3089024A1 (en) | 2018-01-19 | 2019-07-25 | Janssen Pharmaceuticals, Inc. | Induce and enhance immune responses using recombinant replicon systems |
| KR20200144093A (ko) | 2018-02-17 | 2020-12-28 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 막 단백질 전달을 위한 조성물 및 방법 |
| BR112021006614A2 (pt) * | 2018-10-08 | 2021-07-20 | Janssen Pharmaceuticals, Inc. | replicons com base em alfavírus para administração de bioterápicos |
| JP2022513040A (ja) | 2018-11-14 | 2022-02-07 | フラッグシップ パイオニアリング イノベーションズ ブイ， インコーポレイテッド | コンパートメント特異的カーゴ送達のための組成物および方法 |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| MA56535A (fr) * | 2019-06-20 | 2022-04-27 | Janssen Sciences Ireland Unlimited Co | Molécules d'arn à auto-réplication pour vaccins contre le virus de l'hépatite b (vhb) et utilisations associées |
| US11679163B2 (en) | 2019-09-20 | 2023-06-20 | Hdt Bio Corp. | Compositions and methods for delivery of RNA |
| PH12022551208A1 (en) | 2019-11-18 | 2023-04-24 | Janssen Biotech Inc | Vaccines based on mutant calr and jak2 and their uses |
| CA3162690A1 (en) | 2019-12-31 | 2021-07-08 | Minoru S. H. Ko | Temperature-based transient delivery of nucleic acids and proteins to cells and tissues |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| US11759515B2 (en) | 2020-03-09 | 2023-09-19 | Arcturus Therapeutics, Inc. | Compositions and methods for inducing immune responses |
| EP4119166A4 (en) | 2020-03-12 | 2024-06-05 | Institute for Basic Science | COMPOSITION FOR INDUCING APOPTOSIS OF CELLS HAVING GENOMIC SEQUENCE VARIATION AND METHOD FOR INDUCING APOPTOSIS OF CELLS USING THE COMPOSITION |
| CA3172489A1 (en) | 2020-03-23 | 2021-09-30 | Amit KHANDHAR | Nanoemulsion compositions and methods for delivery of nra |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク，インコーポレーテツド | Ｐｓｍａ及びｓｔｅａｐ１ワクチン並びにそれらの使用 |
| WO2021229450A1 (en) | 2020-05-11 | 2021-11-18 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| AU2021271300A1 (en) | 2020-05-11 | 2023-02-02 | Janssen Pharmaceuticals, Inc. | RNA replicon encoding a stabilized corona virus spike protein |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
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| KR20230076812A (ko) * | 2020-07-31 | 2023-05-31 | 레플리케이트 바이오사이언스, 인크. | 변형된 치쿤구니야 바이러스 및 신드비스 바이러스 및 이의 용도 |
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| CN112458064A (zh) * | 2020-11-20 | 2021-03-09 | 广西大学 | 盖他病毒全长感染性克隆、复制子系统及其制备和应用 |
| TW202245809A (zh) | 2020-12-18 | 2022-12-01 | 美商詹森藥物公司 | 用於治療b型肝炎病毒感染之組合療法 |
| CN112852841A (zh) * | 2021-02-03 | 2021-05-28 | 郑州大学 | 一种高效表达目的蛋白的顺式复制子rna构建体 |
| IL309889A (en) * | 2021-07-09 | 2024-03-01 | Replicate Bioscience Inc | Modified eastern equine encephalitis viruses, self-replicating rna constructs, and uses thereof |
| EP4404957A4 (en) | 2021-09-22 | 2025-08-06 | Hdt Bio Corp | CANCER THERAPY COMPOSITIONS AND THEIR USES |
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| WO2025088152A1 (en) | 2023-10-27 | 2025-05-01 | Ziphius Nv | MODIFIED 5'UTRs |
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| AU2017372731B2 (en) | 2016-12-05 | 2024-05-23 | Janssen Pharmaceuticals, Inc. | Compositions and methods for enhancing gene expression |
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| WO2019099624A1 (en) | 2017-11-16 | 2019-05-23 | University Of Washington | A therapeutic vaccine for hepatitis b virus (hbv) using the hbv pres1 and/or pres2, and/or s-hbsag regions of the hbv envelope protein |
| KR20200101416A (ko) | 2017-12-19 | 2020-08-27 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | B형 간염 바이러스(hbv) 백신 및 그 용도 |
| CA3089024A1 (en) * | 2018-01-19 | 2019-07-25 | Janssen Pharmaceuticals, Inc. | Induce and enhance immune responses using recombinant replicon systems |
-
2017
- 2017-10-03 MX MX2019004499A patent/MX2019004499A/es unknown
- 2017-10-03 AU AU2017347725A patent/AU2017347725B2/en active Active
- 2017-10-03 KR KR1020197013847A patent/KR102718353B1/ko active Active
- 2017-10-03 JP JP2019520535A patent/JP7382230B2/ja active Active
- 2017-10-03 CN CN201780075817.7A patent/CN110073002B/zh active Active
- 2017-10-03 WO PCT/US2017/054928 patent/WO2018075235A1/en not_active Ceased
- 2017-10-03 US US15/723,658 patent/US11364310B2/en active Active
- 2017-10-03 BR BR112019007433A patent/BR112019007433A2/pt unknown
- 2017-10-03 ES ES17787724T patent/ES2993107T3/es active Active
- 2017-10-03 EP EP17787724.8A patent/EP3526332B1/en active Active
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2022
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2023
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| Publication number | Publication date |
|---|---|
| AU2017347725B2 (en) | 2024-01-04 |
| JP2023134488A (ja) | 2023-09-27 |
| US20180104359A1 (en) | 2018-04-19 |
| EP3526332B1 (en) | 2024-06-26 |
| JP7382230B2 (ja) | 2023-11-16 |
| JP2019530466A (ja) | 2019-10-24 |
| US11364310B2 (en) | 2022-06-21 |
| US20230126773A1 (en) | 2023-04-27 |
| EP3526332C0 (en) | 2024-06-26 |
| KR102718353B1 (ko) | 2024-10-15 |
| CA3040264A1 (en) | 2018-04-26 |
| BR112019007433A2 (pt) | 2019-07-02 |
| ES2993107T3 (en) | 2024-12-23 |
| AU2017347725A1 (en) | 2019-05-09 |
| WO2018075235A1 (en) | 2018-04-26 |
| CN110073002B (zh) | 2024-06-11 |
| CN110073002A (zh) | 2019-07-30 |
| EP3526332A1 (en) | 2019-08-21 |
| KR20190082226A (ko) | 2019-07-09 |
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