MX2019000806A - Composicion vaginal que comprende una combinacion de estrogeno y vitamina d. - Google Patents

Composicion vaginal que comprende una combinacion de estrogeno y vitamina d.

Info

Publication number
MX2019000806A
MX2019000806A MX2019000806A MX2019000806A MX2019000806A MX 2019000806 A MX2019000806 A MX 2019000806A MX 2019000806 A MX2019000806 A MX 2019000806A MX 2019000806 A MX2019000806 A MX 2019000806A MX 2019000806 A MX2019000806 A MX 2019000806A
Authority
MX
Mexico
Prior art keywords
vitamin
estrogen
combination
vaginal composition
analog
Prior art date
Application number
MX2019000806A
Other languages
English (en)
Inventor
Colli Enrico
F Archer David
Original Assignee
Chemo Res S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Res S L filed Critical Chemo Res S L
Publication of MX2019000806A publication Critical patent/MX2019000806A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/065—Diphenyl-substituted acyclic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una composición vaginal que comprende una combinación de estrógeno y vitamina D o un análogo de vitamina D a un suministro de dosificación diaria de (i) estrógeno que varía desde 1 µg hasta 100 µg de estrógeno de equivalente de estradiol y (ii) vitamina D o análogo que varía desde 7.5 µg hasta 100 µg de equivalente de vitamina D.
MX2019000806A 2016-07-22 2017-07-20 Composicion vaginal que comprende una combinacion de estrogeno y vitamina d. MX2019000806A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16305941.3A EP3272333A1 (en) 2016-07-22 2016-07-22 Vaginal composition comprising a combination of estrogen and vitamin d
PCT/EP2017/068391 WO2018015503A1 (en) 2016-07-22 2017-07-20 Vaginal composition comprising a combination of estrogen and vitamin d

Publications (1)

Publication Number Publication Date
MX2019000806A true MX2019000806A (es) 2019-06-20

Family

ID=56561320

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019000806A MX2019000806A (es) 2016-07-22 2017-07-20 Composicion vaginal que comprende una combinacion de estrogeno y vitamina d.

Country Status (10)

Country Link
US (2) US20190224213A1 (es)
EP (2) EP3272333A1 (es)
BR (1) BR112019001207A2 (es)
CL (1) CL2019000174A1 (es)
CO (1) CO2019000604A2 (es)
CR (1) CR20190026A (es)
MX (1) MX2019000806A (es)
NI (1) NI201900004A (es)
PH (1) PH12019500137A1 (es)
WO (1) WO2018015503A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112088010A (zh) 2018-05-04 2020-12-15 宝洁公司 用于治疗阴道干燥的组合物和方法
CN112135621A (zh) * 2018-05-04 2020-12-25 宝洁公司 用于治疗阴道萎缩的组合物和方法
EP4066824A1 (en) * 2021-03-31 2022-10-05 Dompe' Farmaceutici S.P.A. Combination therapy for covid-19 vaccination

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3062715A (en) 1953-11-18 1962-11-06 George S Pfaus Vaginal tablet
IE61236B1 (en) 1986-07-15 1994-10-19 American Home Prod Combination dosage form for pre-menopausal women
GB8723846D0 (en) 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
US5514698A (en) 1994-03-21 1996-05-07 Ortho Pharmaceutical Corporation Antifungal vaginal cream composition
JP3705620B2 (ja) 1994-12-28 2005-10-12 帝国臓器製薬株式会社 経粘膜投与用製剤
WO1997031631A1 (en) 1996-02-27 1997-09-04 Rpms Technology Limited Cox-2 selective inhibitors for managing labour and uterine contractions
DE19608423A1 (de) 1996-03-05 1997-09-11 Merck Patent Gmbh Implantate mit phasenweiser Arzneistoffabgabe
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US20050276836A1 (en) 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
US20040043071A1 (en) 2002-06-21 2004-03-04 Pauletti Giovanni M. Intravaginal mucosal or transmucosal delivery of antimigraine and antinausea drugs
US6905701B2 (en) 1997-06-11 2005-06-14 Umd, Inc. Formulations for transmucosal vaginal delivery of bisphosphonates
US6197327B1 (en) 1997-06-11 2001-03-06 Umd, Inc. Device and method for treatment of dysmenorrhea
FR2766710B1 (fr) 1997-08-04 1999-10-29 Inst Pharma De Rech Applic Et Composition pharmaceutique, comprime forme a partir de celle-ci et son utilisation comme antiseptique vaginal a action prolongee
DE19916419B4 (de) 1999-04-08 2005-06-16 Schering Ag Kombinationspräparat aus Vitamin-D-Metaboliten oder Vitamin-D-Analoga und einem Östrogenpartialagonisten zur Behandlung von Osteoporose
US6855703B1 (en) * 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
DK1343508T3 (da) * 2000-12-15 2012-02-27 Novo Nordisk Femcare Ag Anvendelse af et østrogen til fremstilling af en sammensætning, der indeholder østrogen, til behandling af atrofisk vaginitis
US7004171B2 (en) 2002-02-25 2006-02-28 Hi-Gienic Intra Vaginal Technologies Ltd. System for transvaginal drug delivery
WO2004103232A1 (en) 2003-05-15 2004-12-02 Apothecus Pharmaceutical Corp. Dissolvable vaginal deodorizing films and methods of vaginal deodorizing utilizing pliable dissolvable film
MXPA06001776A (es) 2003-08-15 2007-09-07 Qlt Usa Inc Sistema de suministro de farmaco transmucosal biocorrosivo, adhesivo.
US20050070501A1 (en) 2003-09-29 2005-03-31 New York Blood Center, Inc. Water dispersible film
US20060040904A1 (en) 2004-08-17 2006-02-23 Ahmed Salah U Vaginal cream compositions, kits thereof and methods of using thereof
BRPI0612968A2 (pt) 2005-04-27 2010-12-14 Shenzhen Phlora Biotechnology Ltd uso do Ácido benzàico e/ou seu sal de sàdio em combinaÇço com sacarÍdeos, composiÇço vaginal e mÉtodo para modular a flora vaginal e a acidez vaginal
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JP2010528052A (ja) 2007-05-24 2010-08-19 ニューヨーク ブラッド センター， インコーポレイテッド 生体接着性ジェルを提供する迅速に分散し得る膣錠剤
US20080312198A1 (en) 2007-06-14 2008-12-18 Rodriguez Gustavo C Pharmaceutical products containing hormones and a 25-hydroxy vitamin d compound
JP5690826B2 (ja) 2009-07-21 2015-03-25 ザ・ポピュレイション・カウンシル，インコーポレイテッド 多層状勾配膣リング
US8980304B2 (en) 2010-08-20 2015-03-17 Teva Women's Health, Inc. Barrel-shaped vaginal ring
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EA027633B1 (ru) 2011-12-29 2017-08-31 Универсидад Де Чиле Вагинальное кольцо, содержащее dhea или сульфат dhea и возможно агент, модулирующий высвобождение активного ингредиента, полезное для увеличения овариального резерва у женщин и для облегчения симптомов, связанных с менопаузой
ITMI20120867A1 (it) 2012-05-18 2013-11-19 Labomar S R L Composizione per il trattamento di lesioni.
FR3018193B1 (fr) 2014-03-10 2017-09-08 Probionov Comprime vaginal muco-adhesif a liberation prolongee
WO2015135470A1 (zh) * 2014-03-13 2015-09-17 曾忠铭 一种阴道用组合物与该组合物的用途
WO2016054002A1 (en) 2014-09-29 2016-04-07 Yale University Progesterone impregnated vaginal ring/pessary

Also Published As

Publication number Publication date
BR112019001207A2 (pt) 2019-04-30
US11590145B2 (en) 2023-02-28
NI201900004A (es) 2019-04-29
US20190224213A1 (en) 2019-07-25
CO2019000604A2 (es) 2019-05-21
CL2019000174A1 (es) 2019-06-28
CR20190026A (es) 2019-04-09
PH12019500137A1 (en) 2019-07-29
EP3272333A1 (en) 2018-01-24
EP3487478A1 (en) 2019-05-29
WO2018015503A1 (en) 2018-01-25
US20210069210A1 (en) 2021-03-11

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