CR20190026A - Composición vaginal que comprende una combinación de estrógeno y vitamina d - Google Patents
Composición vaginal que comprende una combinación de estrógeno y vitamina dInfo
- Publication number
- CR20190026A CR20190026A CR20190026A CR20190026A CR20190026A CR 20190026 A CR20190026 A CR 20190026A CR 20190026 A CR20190026 A CR 20190026A CR 20190026 A CR20190026 A CR 20190026A CR 20190026 A CR20190026 A CR 20190026A
- Authority
- CR
- Costa Rica
- Prior art keywords
- vitamin
- combination
- estrogen
- vaginal composition
- vaginal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/065—Diphenyl-substituted acyclic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención se refiere a no a una composición vaginal que comprende una combinación de estrón-Y vitamina-D y un anánlogo de vitamina-D en una dosis diaria de (i) estrón-que corresponde a 1 µg a 100 µg de deestro-equivalente de estradiol-y (ii) vitamina-Do-anánlogo que corresponde a 7,5 µg a 100 µg de Vitamina-D-equivalencia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16305941.3A EP3272333A1 (en) | 2016-07-22 | 2016-07-22 | Vaginal composition comprising a combination of estrogen and vitamin d |
PCT/EP2017/068391 WO2018015503A1 (en) | 2016-07-22 | 2017-07-20 | Vaginal composition comprising a combination of estrogen and vitamin d |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20190026A true CR20190026A (es) | 2019-04-09 |
Family
ID=56561320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20190026A CR20190026A (es) | 2016-07-22 | 2017-07-20 | Composición vaginal que comprende una combinación de estrógeno y vitamina d |
Country Status (10)
Country | Link |
---|---|
US (2) | US20190224213A1 (es) |
EP (2) | EP3272333A1 (es) |
BR (1) | BR112019001207A2 (es) |
CL (1) | CL2019000174A1 (es) |
CO (1) | CO2019000604A2 (es) |
CR (1) | CR20190026A (es) |
MX (1) | MX2019000806A (es) |
NI (1) | NI201900004A (es) |
PH (1) | PH12019500137A1 (es) |
WO (1) | WO2018015503A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112088010A (zh) | 2018-05-04 | 2020-12-15 | 宝洁公司 | 用于治疗阴道干燥的组合物和方法 |
EP3787659A1 (en) * | 2018-05-04 | 2021-03-10 | The Procter & Gamble Company | Compositions and methods for treating vaginal atrophy |
EP4066824A1 (en) * | 2021-03-31 | 2022-10-05 | Dompe' Farmaceutici S.P.A. | Combination therapy for covid-19 vaccination |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3062715A (en) | 1953-11-18 | 1962-11-06 | George S Pfaus | Vaginal tablet |
IE61236B1 (en) | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
US5514698A (en) | 1994-03-21 | 1996-05-07 | Ortho Pharmaceutical Corporation | Antifungal vaginal cream composition |
JP3705620B2 (ja) | 1994-12-28 | 2005-10-12 | 帝国臓器製薬株式会社 | 経粘膜投与用製剤 |
EP0889724A1 (en) | 1996-02-27 | 1999-01-13 | Rpms Technology Limited | Cox-2 selective inhibitors for managing labour and uterine contractions |
DE19608423A1 (de) | 1996-03-05 | 1997-09-11 | Merck Patent Gmbh | Implantate mit phasenweiser Arzneistoffabgabe |
TW358031B (en) | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
US20050276836A1 (en) | 1997-06-11 | 2005-12-15 | Michelle Wilson | Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents |
US6197327B1 (en) | 1997-06-11 | 2001-03-06 | Umd, Inc. | Device and method for treatment of dysmenorrhea |
US6905701B2 (en) | 1997-06-11 | 2005-06-14 | Umd, Inc. | Formulations for transmucosal vaginal delivery of bisphosphonates |
US20040043071A1 (en) | 2002-06-21 | 2004-03-04 | Pauletti Giovanni M. | Intravaginal mucosal or transmucosal delivery of antimigraine and antinausea drugs |
FR2766710B1 (fr) | 1997-08-04 | 1999-10-29 | Inst Pharma De Rech Applic Et | Composition pharmaceutique, comprime forme a partir de celle-ci et son utilisation comme antiseptique vaginal a action prolongee |
DE19916419B4 (de) | 1999-04-08 | 2005-06-16 | Schering Ag | Kombinationspräparat aus Vitamin-D-Metaboliten oder Vitamin-D-Analoga und einem Östrogenpartialagonisten zur Behandlung von Osteoporose |
US6855703B1 (en) * | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
WO2002047692A1 (en) * | 2000-12-15 | 2002-06-20 | Novo Nordisk A/S | Use of an oestrogen in the manufacture of a composition containing oestrogen for the treatment of atrophic vaginitis |
US7004171B2 (en) | 2002-02-25 | 2006-02-28 | Hi-Gienic Intra Vaginal Technologies Ltd. | System for transvaginal drug delivery |
WO2004103232A1 (en) | 2003-05-15 | 2004-12-02 | Apothecus Pharmaceutical Corp. | Dissolvable vaginal deodorizing films and methods of vaginal deodorizing utilizing pliable dissolvable film |
JP2007502823A (ja) | 2003-08-15 | 2007-02-15 | キューエルティー・ユーエスエイ・インコーポレーテッド | 接着性および生体侵食性の経粘膜薬物送達システム |
US20050070501A1 (en) | 2003-09-29 | 2005-03-31 | New York Blood Center, Inc. | Water dispersible film |
US20060040904A1 (en) | 2004-08-17 | 2006-02-23 | Ahmed Salah U | Vaginal cream compositions, kits thereof and methods of using thereof |
CN101175503B (zh) | 2005-04-27 | 2012-12-12 | 深圳福诺生物技术有限公司 | 一种调节并保持阴道菌群和阴道酸度正常的组合物与方法 |
US20090247493A1 (en) | 2006-01-27 | 2009-10-01 | Duramed Pharmaceuticals, Inc. | Regimens for Treatment of Conditions Related to Estrogen Deficiency |
EP2146698A2 (en) | 2007-05-24 | 2010-01-27 | New York Blood Center, Inc. | Rapidly dispersible vaginal tablet that provides a bioadhesive gel |
US20080312198A1 (en) | 2007-06-14 | 2008-12-18 | Rodriguez Gustavo C | Pharmaceutical products containing hormones and a 25-hydroxy vitamin d compound |
IN2012DN00711A (es) | 2009-07-21 | 2015-06-19 | Population Council Inc | |
US8980304B2 (en) | 2010-08-20 | 2015-03-17 | Teva Women's Health, Inc. | Barrel-shaped vaginal ring |
CN102641548B (zh) | 2011-02-18 | 2016-08-03 | 帕洛阿尔托研究中心公司 | 包括化学品渗透增强剂的透粘膜药物输送装置和方法 |
JP5887424B2 (ja) | 2011-12-29 | 2016-03-16 | ウニベルシダッド デ チリ | Dheaまたは硫酸dheaを有し、かつ有効成分の放出調節薬を任意に有し、女性における卵巣予備能を増やし、かつ閉経期に関連する症状を緩和する膣リング |
EP2799043B1 (en) | 2011-12-29 | 2019-11-27 | Laboratorios Andrómaco S.A. | Vaginal ring including meloxicam and an agent for modulating the release of the active principle, which can be used as a continuous-use contraceptive in women |
ITMI20120867A1 (it) | 2012-05-18 | 2013-11-19 | Labomar S R L | Composizione per il trattamento di lesioni. |
FR3018193B1 (fr) | 2014-03-10 | 2017-09-08 | Probionov | Comprime vaginal muco-adhesif a liberation prolongee |
SG11201607600TA (en) * | 2014-03-13 | 2016-10-28 | Singapore Ze&Z Internat Pte Ltd | Vaginal composition and use thereof |
WO2016054002A1 (en) | 2014-09-29 | 2016-04-07 | Yale University | Progesterone impregnated vaginal ring/pessary |
-
2016
- 2016-07-22 EP EP16305941.3A patent/EP3272333A1/en not_active Withdrawn
-
2017
- 2017-07-20 BR BR112019001207-9A patent/BR112019001207A2/pt active Search and Examination
- 2017-07-20 WO PCT/EP2017/068391 patent/WO2018015503A1/en unknown
- 2017-07-20 EP EP17743316.6A patent/EP3487478A1/en active Pending
- 2017-07-20 MX MX2019000806A patent/MX2019000806A/es unknown
- 2017-07-20 US US16/318,510 patent/US20190224213A1/en not_active Abandoned
- 2017-07-20 CR CR20190026A patent/CR20190026A/es unknown
-
2019
- 2019-01-18 PH PH12019500137A patent/PH12019500137A1/en unknown
- 2019-01-18 NI NI201900004A patent/NI201900004A/es unknown
- 2019-01-22 CL CL2019000174A patent/CL2019000174A1/es unknown
- 2019-01-22 CO CONC2019/0000604A patent/CO2019000604A2/es unknown
-
2020
- 2020-11-19 US US16/952,142 patent/US11590145B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CO2019000604A2 (es) | 2019-05-21 |
CL2019000174A1 (es) | 2019-06-28 |
US20210069210A1 (en) | 2021-03-11 |
US20190224213A1 (en) | 2019-07-25 |
EP3487478A1 (en) | 2019-05-29 |
PH12019500137A1 (en) | 2019-07-29 |
WO2018015503A1 (en) | 2018-01-25 |
MX2019000806A (es) | 2019-06-20 |
NI201900004A (es) | 2019-04-29 |
BR112019001207A2 (pt) | 2019-04-30 |
EP3272333A1 (en) | 2018-01-24 |
US11590145B2 (en) | 2023-02-28 |
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