MX2018013963A - Metodos de inmunoterapia. - Google Patents

Metodos de inmunoterapia.

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Publication number
MX2018013963A
MX2018013963A MX2018013963A MX2018013963A MX2018013963A MX 2018013963 A MX2018013963 A MX 2018013963A MX 2018013963 A MX2018013963 A MX 2018013963A MX 2018013963 A MX2018013963 A MX 2018013963A MX 2018013963 A MX2018013963 A MX 2018013963A
Authority
MX
Mexico
Prior art keywords
methods
immunotherapy
granzyme
cd107a
ifng
Prior art date
Application number
MX2018013963A
Other languages
English (en)
Inventor
Khanna Rajiv
Smith Corey
Original Assignee
Council Queensland Inst Medical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Queensland Inst Medical Res filed Critical Council Queensland Inst Medical Res
Publication of MX2018013963A publication Critical patent/MX2018013963A/es

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • G—PHYSICS
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
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    • G01N2333/90—Enzymes; Proenzymes
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    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
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    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96436—Granzymes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
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  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
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  • Physics & Mathematics (AREA)
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  • Virology (AREA)
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Abstract

Se proporcionan en la presente metodos y composiciones relacionados con la seleccion de celulas T y/o sujetos para inmunoterapia adoptiva basada en la expresion de uno o mas biomarcadores seleccionados de granzima B, granzima K, perforina, CD8, PD-1, TIM-3, LAG-3, CTLA-4, CD107a, IFNg, IL-2, TNF y CD4.
MX2018013963A 2016-05-25 2017-05-25 Metodos de inmunoterapia. MX2018013963A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662341360P 2016-05-25 2016-05-25
US201762487814P 2017-04-20 2017-04-20
PCT/IB2017/000705 WO2017203356A1 (en) 2016-05-25 2017-05-25 Methods of immunotherapy

Publications (1)

Publication Number Publication Date
MX2018013963A true MX2018013963A (es) 2019-08-22

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MX2018013963A MX2018013963A (es) 2016-05-25 2017-05-25 Metodos de inmunoterapia.

Country Status (13)

Country Link
US (1) US11478508B2 (es)
EP (1) EP3465203A4 (es)
JP (2) JP7270382B2 (es)
KR (2) KR102592673B1 (es)
CN (1) CN109477830A (es)
AU (1) AU2017271122B2 (es)
BR (1) BR112018072305A2 (es)
CA (1) CA3023820A1 (es)
MX (1) MX2018013963A (es)
NZ (1) NZ749136A (es)
RU (1) RU2756276C2 (es)
SG (2) SG10202007893TA (es)
WO (1) WO2017203356A1 (es)

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US20210238550A1 (en) * 2018-07-31 2021-08-05 Thyas Co. Ltd. METHOD FOR PRODUCING REGENERATED T CELL POPULATION VIA iPS CELLS

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WO2017203356A1 (en) 2017-11-30
US20210228628A1 (en) 2021-07-29
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BR112018072305A2 (pt) 2019-02-12
US11478508B2 (en) 2022-10-25
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CA3023820A1 (en) 2017-11-30
EP3465203A1 (en) 2019-04-10
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