MX2017014346A - Mejora del efecto de celulas t diseñadas por car por medio de vacunacion con acido nucleico. - Google Patents

Mejora del efecto de celulas t diseñadas por car por medio de vacunacion con acido nucleico.

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Publication number
MX2017014346A
MX2017014346A MX2017014346A MX2017014346A MX2017014346A MX 2017014346 A MX2017014346 A MX 2017014346A MX 2017014346 A MX2017014346 A MX 2017014346A MX 2017014346 A MX2017014346 A MX 2017014346A MX 2017014346 A MX2017014346 A MX 2017014346A
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Mexico
Prior art keywords
antigen
cells
car
nucleic acid
engineered
Prior art date
Application number
MX2017014346A
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English (en)
Inventor
Simon Petra
Hobohm Kathleen
Anna Mroz Karolina
Sahin Ugur
Reinhard Katharina
Original Assignee
Biontech Cell & Gene Therapies Gmbh
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Publication date
Application filed by Biontech Cell & Gene Therapies Gmbh filed Critical Biontech Cell & Gene Therapies Gmbh
Publication of MX2017014346A publication Critical patent/MX2017014346A/es

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Abstract

La presente invención abarca en general el tratamiento de enfermedades al direccionar células que expresan un antígeno en la superficie celular. En particular, la invención se relaciona a un método para estimular, cebar y/o expandir in vivo células T genéticamente modificadas para expresar un receptor de antígeno quimérico (CAR) dirigido a un antígeno, que comprende poner en contacto las células T con el antígeno o una variante del mismo in vivo. En una modalidad, el antígeno o variante del mismo se proporciona al administrar un ácido nucleico que codifica el antígeno o variante del mismo.
MX2017014346A 2015-05-11 2016-05-09 Mejora del efecto de celulas t diseñadas por car por medio de vacunacion con acido nucleico. MX2017014346A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2015/060356 WO2016180467A1 (en) 2015-05-11 2015-05-11 Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
PCT/EP2016/060332 WO2016180778A1 (en) 2015-05-11 2016-05-09 Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination

Publications (1)

Publication Number Publication Date
MX2017014346A true MX2017014346A (es) 2018-04-11

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MX2017014346A MX2017014346A (es) 2015-05-11 2016-05-09 Mejora del efecto de celulas t diseñadas por car por medio de vacunacion con acido nucleico.

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US (2) US10799534B2 (es)
EP (2) EP3294325B1 (es)
JP (1) JP6914851B2 (es)
KR (1) KR20180027414A (es)
CN (2) CN107743399B (es)
AU (3) AU2016259726B2 (es)
BR (1) BR112017023478A2 (es)
CA (1) CA2985156A1 (es)
DK (1) DK3294325T3 (es)
ES (1) ES2952421T3 (es)
FI (1) FI3294325T3 (es)
HK (2) HK1247098A1 (es)
HR (1) HRP20230902T1 (es)
HU (1) HUE062646T2 (es)
LT (1) LT3294325T (es)
MX (1) MX2017014346A (es)
PL (1) PL3294325T3 (es)
PT (1) PT3294325T (es)
RS (1) RS64420B1 (es)
SI (1) SI3294325T1 (es)
WO (2) WO2016180467A1 (es)

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