MX2017011345A - Gen de variante ets2 etv2 y usos del mismo. - Google Patents

Gen de variante ets2 etv2 y usos del mismo.

Info

Publication number
MX2017011345A
MX2017011345A MX2017011345A MX2017011345A MX2017011345A MX 2017011345 A MX2017011345 A MX 2017011345A MX 2017011345 A MX2017011345 A MX 2017011345A MX 2017011345 A MX2017011345 A MX 2017011345A MX 2017011345 A MX2017011345 A MX 2017011345A
Authority
MX
Mexico
Prior art keywords
human
etv2
blastocyst
human animal
null
Prior art date
Application number
MX2017011345A
Other languages
English (en)
Spanish (es)
Inventor
J Garry Daniel
G Garry Mary
Rasmussen Tara
Koyano-Nakagawa Naoko
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of MX2017011345A publication Critical patent/MX2017011345A/es

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877Techniques for producing new mammalian cloned embryos
    • C12N15/8778Swine embryos
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0604Whole embryos; Culture medium therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/15Humanized animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/108Swine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • A01K2267/025Animal producing cells or organs for transplantation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2017011345A 2015-03-03 2016-03-03 Gen de variante ets2 etv2 y usos del mismo. MX2017011345A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562127330P 2015-03-03 2015-03-03
PCT/US2016/020768 WO2016141234A1 (en) 2015-03-03 2016-03-03 Etv2 and uses thereof

Publications (1)

Publication Number Publication Date
MX2017011345A true MX2017011345A (es) 2018-04-24

Family

ID=56848633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011345A MX2017011345A (es) 2015-03-03 2016-03-03 Gen de variante ets2 etv2 y usos del mismo.

Country Status (15)

Country Link
US (2) US11673928B2 (enExample)
EP (1) EP3264891A4 (enExample)
JP (1) JP2018506984A (enExample)
KR (1) KR102684690B1 (enExample)
CN (1) CN108024522A (enExample)
AU (1) AU2016226087A1 (enExample)
BR (1) BR112017018932A2 (enExample)
CA (1) CA2978457A1 (enExample)
CL (1) CL2017002226A1 (enExample)
IL (1) IL254241A0 (enExample)
MX (1) MX2017011345A (enExample)
PH (1) PH12017501589A1 (enExample)
RU (1) RU2017132331A (enExample)
SG (1) SG11201707151YA (enExample)
WO (1) WO2016141234A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017011345A (es) 2015-03-03 2018-04-24 Univ Minnesota Gen de variante ets2 etv2 y usos del mismo.
JP2018523999A (ja) 2015-06-30 2018-08-30 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ヒト化心筋
JP2018522553A (ja) 2015-06-30 2018-08-16 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ヒト化骨格筋
WO2018144860A1 (en) * 2017-02-03 2018-08-09 Cornell University Stable three-dimensional blood vessels and methods for forming the same

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU721375B2 (en) 1996-01-09 2000-06-29 Regents Of The University Of California, The Porcine embryonic stem-like cells, methods of making and using the cells to produce transgenic pigs
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
CN1241210A (zh) 1996-10-11 2000-01-12 得克萨斯农业及机械体系综合大学 产生原生殖细胞和转基因动物物种的方法
JPWO2003034818A1 (ja) * 2001-10-24 2005-02-10 中外製薬株式会社 Sgrf遺伝子改変非ヒト動物
US20040133931A1 (en) 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
AU2003213813A1 (en) 2002-03-22 2003-10-13 St. Jude Children's Research Hospital Improved method for generating genetically modified animals
US20050257279A1 (en) 2002-07-03 2005-11-17 Su Qian Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
GB2398784B (en) 2003-02-26 2005-07-27 Babraham Inst Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal
WO2006014551A2 (en) 2004-07-06 2006-02-09 Michigan State University In vivo methods for effecting tissue specific differentiation of embryonic stem cells
ES2678416T3 (es) 2007-01-11 2018-08-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Células derivadas de músculo para el tratamiento de patologías de las vías urinarias y métodos de fabricación y uso de las mismas
WO2008089482A1 (en) * 2007-01-20 2008-07-24 Boehringer Ingelheim International Gmbh C-reactive protein (crp) knockout mouse
WO2008102602A1 (ja) 2007-02-22 2008-08-28 The University Of Tokyo Blastocyst complementationを利用した臓器再生法
US20110067125A1 (en) * 2008-02-22 2011-03-17 The University Of Tokyo Method for producing founder animal for reproducing animal having lethal phenotype caused by gene modification
GB2490443B8 (en) 2008-08-22 2014-08-13 Univ Tokyo Organ regeneration method utilizing iPS cell and blastocyst complementation
US20120207744A1 (en) 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
WO2010133686A1 (en) 2009-05-20 2010-11-25 Cardio3 Biosciences S.A. Parmaceutical composition for the treatment of heart diseases.
PT2702160T (pt) 2011-04-27 2020-07-30 Amyris Inc Métodos para modificação genómica
SG195252A1 (en) 2011-06-02 2013-12-30 Harvard College Methods and uses for ex vivo tissue culture systems
US9862929B2 (en) 2011-11-18 2018-01-09 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
IL221187A (en) 2012-07-30 2017-01-31 Adom Advanced Optical Tech Ltd A system to perform optical tomography in two 2D beams
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
US11377639B2 (en) 2013-11-15 2022-07-05 Wisconsin Alumni Research Foundation Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
MX2016014066A (es) * 2014-04-28 2017-05-03 Recombinetics Inc Edicion de genes multiples en cerdos.
MX2017011345A (es) 2015-03-03 2018-04-24 Univ Minnesota Gen de variante ets2 etv2 y usos del mismo.
JP2018523999A (ja) 2015-06-30 2018-08-30 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ヒト化心筋
JP2018522553A (ja) 2015-06-30 2018-08-16 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ヒト化骨格筋
JP2019502400A (ja) 2015-10-27 2019-01-31 リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミネソタRegents Of The University Of Minnesota キメラ胚補助臓器作製用の組成物及び方法
CN108125943A (zh) 2018-01-17 2018-06-08 云南省第二人民医院 前胡醇当归脂作为制备抗动脉粥样硬化药物的应用

Also Published As

Publication number Publication date
CL2017002226A1 (es) 2018-07-27
PH12017501589A1 (en) 2018-02-05
WO2016141234A1 (en) 2016-09-09
JP2018506984A (ja) 2018-03-15
CA2978457A1 (en) 2016-09-09
KR20170121262A (ko) 2017-11-01
BR112017018932A2 (pt) 2018-07-31
RU2017132331A (ru) 2019-04-03
SG11201707151YA (en) 2017-09-28
AU2016226087A1 (en) 2017-10-26
IL254241A0 (en) 2017-10-31
US20230365638A1 (en) 2023-11-16
US11673928B2 (en) 2023-06-13
US20180037620A1 (en) 2018-02-08
KR102684690B1 (ko) 2024-07-15
EP3264891A1 (en) 2018-01-10
EP3264891A4 (en) 2018-09-05
CN108024522A (zh) 2018-05-11

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