MX2017011116A - Composiciones novedosas, usos y metodos para hacerlas. - Google Patents

Composiciones novedosas, usos y metodos para hacerlas.

Info

Publication number
MX2017011116A
MX2017011116A MX2017011116A MX2017011116A MX2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A
Authority
MX
Mexico
Prior art keywords
methods
making
novel compositions
present
compounds
Prior art date
Application number
MX2017011116A
Other languages
English (en)
Spanish (es)
Inventor
Haddach Mustapha
Original Assignee
Pimera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pimera Inc filed Critical Pimera Inc
Publication of MX2017011116A publication Critical patent/MX2017011116A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2017011116A 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas. MX2017011116A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562128208P 2015-03-04 2015-03-04
PCT/US2016/020418 WO2016141042A2 (en) 2015-03-04 2016-03-02 Novel compositions, uses and methods for making them

Publications (1)

Publication Number Publication Date
MX2017011116A true MX2017011116A (es) 2018-05-28

Family

ID=56848519

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011116A MX2017011116A (es) 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas.

Country Status (7)

Country Link
US (9) US9758518B2 (enExample)
EP (1) EP3300501A4 (enExample)
JP (2) JP6878288B2 (enExample)
CN (1) CN107567448B (enExample)
CA (1) CA2978571C (enExample)
MX (1) MX2017011116A (enExample)
WO (1) WO2016141042A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106588920B (zh) * 2016-12-27 2018-10-30 云南大学 1,3-二氮杂环并[1,2-a]喹啉类化合物及其制备方法和抗肿瘤应用
JP2020512975A (ja) * 2017-03-28 2020-04-30 ピメラ,インク. Pol1阻害剤の新規な結晶形態
WO2020160175A1 (en) * 2019-01-29 2020-08-06 Arizona Board Of Regents On Behalf Of The University Of Arizona Quindoline compounds and uses thereof
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
US12173005B1 (en) 2023-12-21 2024-12-24 King Faisal University Pyrimido[1′,6′:1,5]pyrazolo[4,3-b][1,7]naphthyridine compounds as CK2 inhibitors

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1042801A (en) 1909-10-28 1912-10-29 Isidor Kitsee Protecting kinematographic films.
NL7709746A (nl) 1976-09-09 1978-03-13 Hoechst Ag Werkwijze ter bereiding van benzimidazo-(1,2-a)-chi- nolinen.
DE2929414A1 (de) 1979-07-20 1981-02-05 Hoechst Ag Pyrimido- eckige klammer auf 5',4' zu 5,6 eckige klammer zu -pyrido- eckige klammer auf 1,2-a eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung und deren verwendung
DE3502689A1 (de) 1985-01-26 1986-07-31 Hoechst Ag, 6230 Frankfurt Elektrophotographisches aufzeichnungsmaterial
DE19509043A1 (de) 1995-03-03 1996-09-05 Bayer Ag Cyanierung von Doppelbindungssystemen
US5624677A (en) 1995-06-13 1997-04-29 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
ES2260300T3 (es) 2000-10-03 2006-11-01 Bristol-Myers Squibb Company Compuestos tetraciclicos sustituidos con amino utiles como agentes antiinflamatorios y composiciones farmaceuticas que comprenden los mismos.
US7354916B2 (en) 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
WO2004091504A2 (en) 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs
US7507727B2 (en) 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
US7652134B2 (en) 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
BRPI0515319A (pt) 2004-09-17 2008-07-22 Cylene Pharmaceuticals Inc análogos de quinolona
CA2604787A1 (en) 2005-04-15 2006-10-26 Cylene Pharmaceuticals, Inc. Quinobenzoxazine analogs and methods of using thereof
DK1928887T3 (en) 2005-08-05 2015-03-23 Senhwa Biosciences Inc Methods for preparing quinolonanaloger
EP2270014A1 (en) 2005-09-22 2011-01-05 Incyte Corporation Azepine inhibitors of janus kinases
US8142909B2 (en) 2006-02-10 2012-03-27 Universal Display Corporation Blue phosphorescent imidazophenanthridine materials
WO2007125405A2 (en) 2006-05-01 2007-11-08 Pfizer Products Inc. Substituted 2-amino-fused heterocyclic compounds
US20100063046A1 (en) 2006-05-17 2010-03-11 Whitten Jeffrey P Tetracyclic imidazole analogs
WO2009046383A1 (en) 2007-10-05 2009-04-09 Cylene Pharmaceuticals, Inc. Quinolone analogs and methods related thereto
EP2328890B1 (en) 2008-08-06 2012-01-25 Pfizer Inc. 6 substituted 2-heterocyclylamino pyrazine compounds as chk-1 inhibitors
EP2311826B1 (en) 2008-11-03 2017-05-24 LG Chem, Ltd. Novel nitrogen-containing heterocyclic compound and organic electronic device using the same
US8124770B2 (en) 2009-04-01 2012-02-28 Beatriz Zayas Fluorescent cellular markers
CN101781312B (zh) 2009-12-30 2012-09-26 中国科学院广州生物医药与健康研究院 一种吲哚衍生物的合成方法
US8637529B2 (en) 2010-06-11 2014-01-28 AbbYie Inc. Pyrazolo[3,4-d]pyrimidine compounds
KR101567610B1 (ko) * 2010-11-04 2015-11-09 주식회사 엘지화학 신규한 질소 함유 헤테로환 화합물 및 이를 이용한 유기 전자 소자
EA201490610A1 (ru) 2011-10-21 2014-09-30 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Соединения и способы усиления врожденных иммунных ответов
KR101561730B1 (ko) 2012-02-06 2015-10-22 주식회사 엘지화학 질소원소를 함유한 헤테로고리 유도체 및 이를 이용한 유기 전자 소자
ES2754207T3 (es) 2013-11-28 2020-04-16 Tel Hashomer Medical Res Infrastructure & Services Ltd Inhibidores de la ARN polimerasa I y usos de los mismos
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
PE20170131A1 (es) 2014-05-09 2017-03-19 Pimera Inc Composiciones novedosas usos y metodos para hacerlas
CN106349244B (zh) 2015-07-13 2018-07-27 首都医科大学 苯并咪唑并喹唑啉二甲氧苯氧乙酰-AA-OBzl,其合成,活性和应用
KR20180113976A (ko) 2015-11-20 2018-10-17 센화 바이오사이언시즈 인코포레이티드 암을 치료하기 위한 테트라사이클릭 퀴놀론 유사체의 병행 요법
JP2020512975A (ja) 2017-03-28 2020-04-30 ピメラ,インク. Pol1阻害剤の新規な結晶形態

Also Published As

Publication number Publication date
US11623928B2 (en) 2023-04-11
US20190389860A1 (en) 2019-12-26
JP2021066741A (ja) 2021-04-30
US10745403B2 (en) 2020-08-18
US20210094952A1 (en) 2021-04-01
US20180079750A1 (en) 2018-03-22
US20200361937A1 (en) 2020-11-19
US9758518B2 (en) 2017-09-12
US10975076B2 (en) 2021-04-13
EP3300501A4 (en) 2019-04-17
US10442801B2 (en) 2019-10-15
WO2016141042A4 (en) 2016-12-15
HK1247927A1 (zh) 2018-10-05
JP2018507230A (ja) 2018-03-15
WO2016141042A3 (en) 2016-11-03
CA2978571C (en) 2023-10-03
US9951066B2 (en) 2018-04-24
US10590134B2 (en) 2020-03-17
CA2978571A1 (en) 2016-09-09
US20170334905A1 (en) 2017-11-23
WO2016141042A2 (en) 2016-09-09
US11618752B2 (en) 2023-04-04
US20160257678A1 (en) 2016-09-08
CN107567448B (zh) 2021-06-08
US20210317120A1 (en) 2021-10-14
EP3300501A2 (en) 2018-04-04
CN107567448A (zh) 2018-01-09
US20180291020A1 (en) 2018-10-11
JP6878288B2 (ja) 2021-05-26
US20190233422A1 (en) 2019-08-01
US11866438B2 (en) 2024-01-09

Similar Documents

Publication Publication Date Title
PH12017500660A1 (en) Novel compositions, uses and methods for making them
PH12018500907A1 (en) Inhibitors of ret
MX2020005213A (es) Inhibidores de proteina cinasa 2 activada por proteina cinasa activada por mitogeno (mk2) y sus usos.
HK1255162A1 (zh) 爱帕琳肽受体激动剂及使用方法
MY189454A (en) 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as apj agonists
MX2018001890A (es) Compuestos biciclicos como inhibidores de autotaxina (atx).
PH12018500408A1 (en) Bicyclic compounds as atx inhibitors
SG10201908839QA (en) 2,4-dihydroxy-nicotinamides as apj agonists
MX2018006632A (es) Inhibidores biciclicos de peptidilarginina deiminasa 4 (pad4).
PH12018500409A1 (en) New bicyclic compounds as dual atx/ca inhibitors
WO2015120062A8 (en) Therapeutic compounds and compositions
MX2017011116A (es) Composiciones novedosas, usos y metodos para hacerlas.
NZ763528A (en) Heterocyclic gpr119 agonist compounds
MX2018004674A (es) Moduladores de interacción de sestrina-gator2 y sus usos.
MX2017008390A (es) Uretanos funcionalizados con alcoxisilano y funcionalizados con alofanato.
TN2018000057A1 (en) Compounds useful for inhibiting ror-gamma-t.
PH12016501613B1 (en) Pyrazines modulators of gpr6
PH12018500406A1 (en) Bicyclic compounds as atx inhibitors
PH12018500407A1 (en) New bicyclic compounds as dual atx/ca inhibitors
MX2016015468A (es) Composiciones farmaceuticas que contienen montelukast y levocetirizina.
IN2014MU00815A (enExample)
IN2014MU00814A (enExample)