MX2017011116A - Composiciones novedosas, usos y metodos para hacerlas. - Google Patents

Composiciones novedosas, usos y metodos para hacerlas.

Info

Publication number
MX2017011116A
MX2017011116A MX2017011116A MX2017011116A MX2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A MX 2017011116 A MX2017011116 A MX 2017011116A
Authority
MX
Mexico
Prior art keywords
methods
making
novel compositions
present
compounds
Prior art date
Application number
MX2017011116A
Other languages
English (en)
Spanish (es)
Inventor
Haddach Mustapha
Original Assignee
Pimera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pimera Inc filed Critical Pimera Inc
Publication of MX2017011116A publication Critical patent/MX2017011116A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2017011116A 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas. MX2017011116A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562128208P 2015-03-04 2015-03-04
PCT/US2016/020418 WO2016141042A2 (en) 2015-03-04 2016-03-02 Novel compositions, uses and methods for making them

Publications (1)

Publication Number Publication Date
MX2017011116A true MX2017011116A (es) 2018-05-28

Family

ID=56848519

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011116A MX2017011116A (es) 2015-03-04 2016-03-02 Composiciones novedosas, usos y metodos para hacerlas.

Country Status (7)

Country Link
US (9) US9758518B2 (enExample)
EP (1) EP3300501A4 (enExample)
JP (2) JP6878288B2 (enExample)
CN (1) CN107567448B (enExample)
CA (1) CA2978571C (enExample)
MX (1) MX2017011116A (enExample)
WO (1) WO2016141042A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106588920B (zh) * 2016-12-27 2018-10-30 云南大学 1,3-二氮杂环并[1,2-a]喹啉类化合物及其制备方法和抗肿瘤应用
EP3601286A4 (en) * 2017-03-28 2020-09-23 Pimera, Inc. NEW CRYSTALLINE FORMS OF A POL1 INHIBITOR
WO2020160174A1 (en) * 2019-01-29 2020-08-06 Universita Degli Studi Di Padova Uses of compounds having anti-hsv-1 activity
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
US12173005B1 (en) 2023-12-21 2024-12-24 King Faisal University Pyrimido[1′,6′:1,5]pyrazolo[4,3-b][1,7]naphthyridine compounds as CK2 inhibitors

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1042801A (en) 1909-10-28 1912-10-29 Isidor Kitsee Protecting kinematographic films.
NL7709746A (nl) 1976-09-09 1978-03-13 Hoechst Ag Werkwijze ter bereiding van benzimidazo-(1,2-a)-chi- nolinen.
DE2929414A1 (de) 1979-07-20 1981-02-05 Hoechst Ag Pyrimido- eckige klammer auf 5',4' zu 5,6 eckige klammer zu -pyrido- eckige klammer auf 1,2-a eckige klammer zu -benzimidazole, verfahren zu ihrer herstellung und deren verwendung
DE3502689A1 (de) 1985-01-26 1986-07-31 Hoechst Ag, 6230 Frankfurt Elektrophotographisches aufzeichnungsmaterial
DE19509043A1 (de) 1995-03-03 1996-09-05 Bayer Ag Cyanierung von Doppelbindungssystemen
US5624677A (en) 1995-06-13 1997-04-29 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
US6960585B2 (en) 2000-10-03 2005-11-01 Bristol-Myers Squibb Company Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same
US7507727B2 (en) 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
US7354916B2 (en) 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
NZ543006A (en) 2003-04-07 2009-03-31 Cylene Pharmaceuticals Inc Substituted quinobenzoxazine analogs
AU2005286965B2 (en) 2004-09-17 2009-10-22 Senhwa Biosciences, Inc. Quinolone analogs as cell proliferation inhibitors
US7652134B2 (en) 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
US7402579B2 (en) 2005-04-15 2008-07-22 Cylene Pharmaceuticals, Inc. Quinobenzoxazine analogs and compositions
EP1928887B1 (en) 2005-08-05 2014-12-17 Senhwa Biosciences, Inc. Methods of preparing quinolone analogs
JP5119154B2 (ja) 2005-09-22 2013-01-16 インサイト・コーポレイション Janusキナーゼの四環系阻害剤
US8142909B2 (en) 2006-02-10 2012-03-27 Universal Display Corporation Blue phosphorescent imidazophenanthridine materials
CA2651072A1 (en) 2006-05-01 2007-11-08 Pfizer Products Inc. Substituted 2-amino-fused heterocyclic compounds
US20100063046A1 (en) 2006-05-17 2010-03-11 Whitten Jeffrey P Tetracyclic imidazole analogs
DK3092901T3 (da) 2007-10-05 2020-05-18 Senhwa Biosciences Inc Quinolonanaloger og fremgangsmåder relateret dertil
ES2378513T3 (es) 2008-08-06 2012-04-13 Pfizer Inc. Compuestos 2-heterociclilamino piracinas sustituidas en posición 6 como inhibidores de CHK-1
CN102119158B (zh) 2008-11-03 2015-09-09 株式会社Lg化学 含氮杂环化合物及使用该化合物的有机电子器件
US8124770B2 (en) 2009-04-01 2012-02-28 Beatriz Zayas Fluorescent cellular markers
CN101781312B (zh) 2009-12-30 2012-09-26 中国科学院广州生物医药与健康研究院 一种吲哚衍生物的合成方法
US8637529B2 (en) 2010-06-11 2014-01-28 AbbYie Inc. Pyrazolo[3,4-d]pyrimidine compounds
KR101567610B1 (ko) * 2010-11-04 2015-11-09 주식회사 엘지화학 신규한 질소 함유 헤테로환 화합물 및 이를 이용한 유기 전자 소자
PE20141359A1 (es) 2011-10-21 2014-10-13 Glaxosmithkline Llc Compuestos y metodos para mejorar las respuestas inmunitarias innatas
KR101561730B1 (ko) 2012-02-06 2015-10-22 주식회사 엘지화학 질소원소를 함유한 헤테로고리 유도체 및 이를 이용한 유기 전자 소자
WO2015079411A1 (en) 2013-11-28 2015-06-04 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
CN106995443B (zh) 2014-05-09 2022-01-11 皮梅拉股份有限公司 新组合物、用途和制备它们的方法
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN106349244B (zh) 2015-07-13 2018-07-27 首都医科大学 苯并咪唑并喹唑啉二甲氧苯氧乙酰-AA-OBzl,其合成,活性和应用
WO2017087235A1 (en) 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
EP3601286A4 (en) 2017-03-28 2020-09-23 Pimera, Inc. NEW CRYSTALLINE FORMS OF A POL1 INHIBITOR

Also Published As

Publication number Publication date
JP2018507230A (ja) 2018-03-15
US9951066B2 (en) 2018-04-24
US9758518B2 (en) 2017-09-12
US10975076B2 (en) 2021-04-13
US20190389860A1 (en) 2019-12-26
WO2016141042A3 (en) 2016-11-03
WO2016141042A2 (en) 2016-09-09
CN107567448A (zh) 2018-01-09
US11618752B2 (en) 2023-04-04
US20170334905A1 (en) 2017-11-23
CA2978571A1 (en) 2016-09-09
US10745403B2 (en) 2020-08-18
US20160257678A1 (en) 2016-09-08
US20190233422A1 (en) 2019-08-01
US20180291020A1 (en) 2018-10-11
US10442801B2 (en) 2019-10-15
US20210094952A1 (en) 2021-04-01
JP6878288B2 (ja) 2021-05-26
US20210317120A1 (en) 2021-10-14
US20200361937A1 (en) 2020-11-19
EP3300501A4 (en) 2019-04-17
US11866438B2 (en) 2024-01-09
US20180079750A1 (en) 2018-03-22
WO2016141042A4 (en) 2016-12-15
CA2978571C (en) 2023-10-03
US10590134B2 (en) 2020-03-17
JP2021066741A (ja) 2021-04-30
EP3300501A2 (en) 2018-04-04
US11623928B2 (en) 2023-04-11
CN107567448B (zh) 2021-06-08
HK1247927A1 (zh) 2018-10-05

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