MX2017006463A - Cuantificacion de porcion de glicano en glicoproteinas recombinantes. - Google Patents

Cuantificacion de porcion de glicano en glicoproteinas recombinantes.

Info

Publication number
MX2017006463A
MX2017006463A MX2017006463A MX2017006463A MX2017006463A MX 2017006463 A MX2017006463 A MX 2017006463A MX 2017006463 A MX2017006463 A MX 2017006463A MX 2017006463 A MX2017006463 A MX 2017006463A MX 2017006463 A MX2017006463 A MX 2017006463A
Authority
MX
Mexico
Prior art keywords
quantitation
glycan moiety
recombinant glycoproteins
moiety
glycan
Prior art date
Application number
MX2017006463A
Other languages
English (en)
Inventor
Chemmalil Letha
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2017006463A publication Critical patent/MX2017006463A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La invención se trata de un método para determinar la porción de glicano en una glicoproteína recombinante usando detección de dispersión de luz de formación de núcleos por condensación.
MX2017006463A 2014-11-19 2015-11-19 Cuantificacion de porcion de glicano en glicoproteinas recombinantes. MX2017006463A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462082014P 2014-11-19 2014-11-19
PCT/US2015/061684 WO2016081770A1 (en) 2014-11-19 2015-11-19 Quantitation of glycan moiety in recombinant glycoproteins

Publications (1)

Publication Number Publication Date
MX2017006463A true MX2017006463A (es) 2018-04-20

Family

ID=54754830

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017006463A MX2017006463A (es) 2014-11-19 2015-11-19 Cuantificacion de porcion de glicano en glicoproteinas recombinantes.

Country Status (9)

Country Link
US (1) US11275090B2 (es)
EP (2) EP3540071B1 (es)
JP (2) JP2018502287A (es)
AU (1) AU2015349809B2 (es)
CA (1) CA2968372A1 (es)
ES (2) ES2962593T3 (es)
HK (1) HK1244037B (es)
MX (1) MX2017006463A (es)
WO (1) WO2016081770A1 (es)

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CN107045019B (zh) * 2016-09-30 2019-08-16 中国医学科学院输血研究所 一种IVIG中IgG Fab片段和Fc片段唾液酸含量的测定方法
CN106908528A (zh) * 2017-02-14 2017-06-30 信达生物制药(苏州)有限公司 蛋白类药物中唾液酸的检测方法
KR101923662B1 (ko) * 2017-12-28 2018-11-30 (주)글라이칸 비인간형 당사슬 NeuGc를 포함하는 시알산 고감도 분석방법 및 이를 이용한 분석용 킷트
JP7343890B2 (ja) * 2019-04-26 2023-09-13 国立大学法人東海国立大学機構 シアリダーゼ活性を有する酵素剤及びその利用
WO2020251862A1 (en) * 2019-06-14 2020-12-17 Agilent Technologies, Inc. Methods and kits to improve the fluorescent signal of dmb-labeled sialic acids

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AU588819B2 (en) 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
US4968607A (en) 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
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US6204363B1 (en) 1989-10-16 2001-03-20 Amgen Inc. Stem cell factor
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MX2011007545A (es) 2009-01-22 2011-10-28 Momenta Pharmaceuticals Inc N-glicanos que contienen galactosa-alfa-1,3-galactosa en productos de glicoproteina derivados de celulas de ovario de hamster chino (cho).
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Also Published As

Publication number Publication date
ES2727380T3 (es) 2019-10-15
AU2015349809B2 (en) 2022-02-10
EP3221465B1 (en) 2019-03-13
EP3540071B1 (en) 2023-09-06
ES2962593T3 (es) 2024-03-20
JP2018502287A (ja) 2018-01-25
JP7055837B2 (ja) 2022-04-18
AU2015349809A1 (en) 2017-05-25
JP2020187128A (ja) 2020-11-19
EP3221465A1 (en) 2017-09-27
HK1244037B (zh) 2019-11-15
CA2968372A1 (en) 2016-05-26
US11275090B2 (en) 2022-03-15
US20180321252A1 (en) 2018-11-08
WO2016081770A1 (en) 2016-05-26
EP3540071A1 (en) 2019-09-18

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