MX2017003666A - Esteviol glicosidos de alta pureza. - Google Patents

Esteviol glicosidos de alta pureza.

Info

Publication number
MX2017003666A
MX2017003666A MX2017003666A MX2017003666A MX2017003666A MX 2017003666 A MX2017003666 A MX 2017003666A MX 2017003666 A MX2017003666 A MX 2017003666A MX 2017003666 A MX2017003666 A MX 2017003666A MX 2017003666 A MX2017003666 A MX 2017003666A
Authority
MX
Mexico
Prior art keywords
steviol glycosides
reb
methods
highly purified
rebaudiosides
Prior art date
Application number
MX2017003666A
Other languages
English (en)
Inventor
Markosyan Avetik
Prakash Indra
Jarrin Cyrille
Bunders Cynthia
Badie Aurelien
Ter Halle Robert
Auriol Daniel
Original Assignee
Purecircle Sdn Bhd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2015/045906 external-priority patent/WO2016028899A1/en
Application filed by Purecircle Sdn Bhd filed Critical Purecircle Sdn Bhd
Publication of MX2017003666A publication Critical patent/MX2017003666A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Seasonings (AREA)

Abstract

Se describen métodos para preparar esteviol glicosidos altamente purificados, particularmente Rebaudiosidos A, D y M. Los métodos incluyen la utilización de microorganismos recombinantes para convertir varias composiciones de partida a estivol glicosidos objetivo. Además, se describen estivol glicosidos novedosos Reb D2, Reb M2 y Reb I, así como métodos para preparar los mismos. Los rebaudiosidos altamente purificados son útiles como edulcorantes no calórico en composiciones comestibles y masticables tales como cualquiera de bebidas, confituras, productos de panadería, galletitas y gomas de mascar.
MX2017003666A 2014-09-19 2015-08-21 Esteviol glicosidos de alta pureza. MX2017003666A (es)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201462052544P 2014-09-19 2014-09-19
US201462061359P 2014-10-08 2014-10-08
US201462062288P 2014-10-10 2014-10-10
US201462064630P 2014-10-16 2014-10-16
US201462082446P 2014-11-20 2014-11-20
US201462097387P 2014-12-29 2014-12-29
US201562118132P 2015-02-19 2015-02-19
US201562185964P 2015-06-29 2015-06-29
PCT/US2015/045906 WO2016028899A1 (en) 2014-08-19 2015-08-19 Methods for preparing rebaudioside i and uses
PCT/US2015/046354 WO2016043926A1 (en) 2014-09-19 2015-08-21 High-purity steviol glycosides

Publications (1)

Publication Number Publication Date
MX2017003666A true MX2017003666A (es) 2018-02-01

Family

ID=55533681

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017003666A MX2017003666A (es) 2014-09-19 2015-08-21 Esteviol glicosidos de alta pureza.
MX2022001230A MX2022001230A (es) 2014-09-19 2017-03-17 Esteviol glicosidos de alta pureza.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022001230A MX2022001230A (es) 2014-09-19 2017-03-17 Esteviol glicosidos de alta pureza.

Country Status (6)

Country Link
US (1) US11653679B2 (es)
EP (2) EP4166010A1 (es)
CN (2) CN107105734A (es)
BR (1) BR112017005656A2 (es)
MX (2) MX2017003666A (es)
WO (1) WO2016043926A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9752174B2 (en) * 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
US10264811B2 (en) 2014-05-19 2019-04-23 Epc Natural Products Co., Ltd. Stevia sweetener with improved solubility
CN107249356B (zh) 2014-12-17 2021-08-06 嘉吉公司 用于口服摄入或使用的甜菊醇糖苷化合物、组合物以及用于增强甜菊醇糖苷溶解度的方法
BR112017021066B1 (pt) 2015-04-03 2022-02-08 Dsm Ip Assets B.V. Glicosídeos de esteviol, método para a produção de um glicosídeo de esteviol, composição, usos relacionados, gênero alimentício, alimento para animais e bebida
EP3458599A1 (en) 2016-05-16 2019-03-27 Evolva SA Production of steviol glycosides in recombinant hosts
US11299723B2 (en) 2016-06-15 2022-04-12 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
JP7107855B2 (ja) * 2016-06-17 2022-07-27 カーギル インコーポレイテッド 経口摂取のためのステビオール配糖体組成物または使用
ES2964976T3 (es) * 2016-10-14 2024-04-10 Conagen Inc Producción biosintética de glucósidos de esteviol y procesos para el mismo
US11542536B2 (en) 2016-12-14 2023-01-03 The Coca-Cola Company Preparing novel steviol glycosides by bioconversion
CN110914445B (zh) 2017-02-03 2024-08-27 泰莱解决方案美国有限责任公司 工程化糖基转移酶和甜菊醇糖苷葡糖基化方法
MX2019010537A (es) 2017-03-06 2019-11-21 Conagen Inc Produccion biosintetica del rebaudiosido d4 de glucosido de esteviol a partir del rebaudiosido e.
EP3624599A4 (en) * 2017-05-15 2020-11-18 PureCircle USA Inc. HIGHLY PURE STEVIOL GLYCOSIDE
CN110809408B (zh) * 2017-06-30 2024-09-10 科纳根公司 通过β-葡糖苷酶水解甜菊醇糖苷
GB201805578D0 (en) * 2018-04-04 2018-05-16 Optibiotix Health Ltd Prebiotic compositions and methods of production thereof
EP3813545A4 (en) * 2018-05-08 2023-03-22 EPC Natural Products Co., Ltd. STEVIOL GLYCOSIDE COMPOSITIONS WITH ENHANCED FLAVOR
EP3973069A4 (en) * 2019-05-23 2023-09-13 Arzeda Corp. COMPOSITIONS AND METHODS FOR PRODUCING STEVIOL GLYCOSIDES
KR102709594B1 (ko) * 2019-06-25 2024-09-26 마누스 바이오, 인크. 우리딘 다이포스페이트-의존성 글라이코실트랜스퍼라제 효소
CN110592043B (zh) * 2019-11-01 2022-10-18 广西师范大学 一种udp-葡萄糖基转移酶突变体及其应用
CN110872586B (zh) * 2019-11-11 2024-01-30 天津大学 固定化葡萄糖基转移酶及制备方法及催化生产莱鲍迪苷d的方法
CN114703159B (zh) * 2022-03-15 2023-05-26 林影 一种葡糖基转移酶突变体及其应用
CN115975972B (zh) * 2022-12-20 2023-07-25 杭州力文所生物科技有限公司 一种糖基转移酶突变体及其编码基因

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3101023B1 (en) 2008-10-03 2023-08-30 Morita Kagaku Kogyo Co., Ltd. New steviol glycosides
NZ708078A (en) * 2010-06-02 2017-01-27 Evolva Nutrition Inc Recombinant production of steviol glycosides
BR112014003037B1 (pt) * 2011-08-08 2022-04-05 Evolva Sa Hospedeiro recombinante e método para produzir um glicosídeo de esteviol
CN103159808B (zh) * 2011-12-09 2017-03-29 上海泓博智源医药股份有限公司 一种制备天然甜味剂的工艺方法
CN104684414A (zh) 2011-12-19 2015-06-03 可口可乐公司 纯化甜叶菊醇糖苷的方法和其用途
EP3444338A1 (en) 2012-01-23 2019-02-20 DSM IP Assets B.V. Diterpene production
US9752174B2 (en) * 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
MX352678B (es) * 2012-05-22 2017-12-04 Purecircle Sdn Bhd Glucosidos de esteviol de alta pureza.
EP2954058B1 (en) * 2013-02-06 2021-03-31 Evolva SA Methods for improved production of rebaudioside d and rebaudioside m
US9717267B2 (en) 2013-03-14 2017-08-01 The Coca-Cola Company Beverages containing rare sugars
US10570164B2 (en) 2013-03-15 2020-02-25 The Coca-Cola Company Steviol glycosides, their compositions and their purification
US10683323B2 (en) 2013-03-15 2020-06-16 The Coca-Cola Company Mogrosides, compositions and their purification
US9522929B2 (en) 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
JP7107855B2 (ja) * 2016-06-17 2022-07-27 カーギル インコーポレイテッド 経口摂取のためのステビオール配糖体組成物または使用
ES2906310T3 (es) * 2016-08-12 2022-04-18 Amyris Inc Glicosiltransferasa dependiente de UDP para la producción de alta eficiencia de rebaudiósidos
MX2019010537A (es) * 2017-03-06 2019-11-21 Conagen Inc Produccion biosintetica del rebaudiosido d4 de glucosido de esteviol a partir del rebaudiosido e.
CN110809408B (zh) * 2017-06-30 2024-09-10 科纳根公司 通过β-葡糖苷酶水解甜菊醇糖苷

Also Published As

Publication number Publication date
US20170303565A1 (en) 2017-10-26
US11653679B2 (en) 2023-05-23
WO2016043926A1 (en) 2016-03-24
CN107105734A (zh) 2017-08-29
BR112017005656A2 (pt) 2018-07-31
MX2022001230A (es) 2022-03-02
EP3193636B1 (en) 2022-07-06
EP3193636A4 (en) 2018-06-20
CN113549664A (zh) 2021-10-26
EP4166010A1 (en) 2023-04-19
EP3193636A1 (en) 2017-07-26

Similar Documents

Publication Publication Date Title
MX2022001230A (es) Esteviol glicosidos de alta pureza.
MX2019005688A (es) Glicosidos de esteviol de alta pureza.
BR112014028819A2 (pt) glicosídeos de esteviol de pureza elevada
MY190650A (en) Steviol glycoside compositions for oral ingestion or use
MX346137B (es) Rebaudiosido d altamente soluble.
PH12019550239A1 (en) High-purity steviol glycosides
WO2018102447A3 (en) Food ingredients from stevia rebaudiana
MX2016000825A (es) Glicosidos de esteviol.
MY183009A (en) Sweetener and sweetened compositions incorporating rebaudoside n
MY190567A (en) Non-caloric sweeteners and methods for synthesizing
MY190181A (en) Steviol glycoside compositions for oral ingestion or use
MY193955A (en) Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility
WO2016038095A3 (en) Production of steviol glycosides in recombinant hosts
NZ725866A (en) A non-caloric sweetener
BR112016012682A2 (pt) Composto adoçante
EP3478700A4 (en) STEVIOL GLYCOSIDE COMPOSITIONS FOR ORAL INGESTION OR USE
EP3611179A4 (en) NOVEL STEVIOL GLYCOSIDE AND THE MANUFACTURING PROCESS FOR IT AND THE SWEETENER COMPOSITION WITH IT
EP3644758A4 (en) HYDROLYSIS OF STEVIOL GLYCOSIDES BY BETA-GLUCOSIDASE
EP3564251A4 (en) NOVEL STEVIOL GLYCOSIDE, METHOD FOR MANUFACTURING THEREOF AND SWEETENING COMPOSITION THEREOF
EP4275516A3 (en) Steviol glycoside compositions
MX2020009635A (es) Glucosidos de esteviol de alta pureza.
MX2017016588A (es) Novedosos glucosidos de triterpeno como edulcorantes o potenciador de edulcorante.
WO2013088246A3 (en) Process for the purification of rebaudioside a and compositions thereof
EP3813545A4 (en) STEVIOL GLYCOSIDE COMPOSITIONS WITH ENHANCED FLAVOR