MX2016012840A - Moléculas para transporte de antígeno modular mejoradas y sus usos. - Google Patents
Moléculas para transporte de antígeno modular mejoradas y sus usos.Info
- Publication number
- MX2016012840A MX2016012840A MX2016012840A MX2016012840A MX2016012840A MX 2016012840 A MX2016012840 A MX 2016012840A MX 2016012840 A MX2016012840 A MX 2016012840A MX 2016012840 A MX2016012840 A MX 2016012840A MX 2016012840 A MX2016012840 A MX 2016012840A
- Authority
- MX
- Mexico
- Prior art keywords
- molecules
- imat
- module
- improved modular
- prevention
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/06—Fusion polypeptide containing a localisation/targetting motif containing a lysosomal/endosomal localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Abstract
La presente invención se refiere a proteínas recombinantes (aisladas), también denominadas como moléculas MAT mejoradas (iMAT), que comprende al menos un módulo de translocación, al menos un módulo de direccionamiento y al menos un módulo del antígeno, en donde al menos un residuo de cisteína se sustituye con un residuo de aminoácido diferente. Tales moléculas iMAT son útiles específicamente como vacunas, por ejemplo, para terapia y/o prevención de alegrías y/o enfermedades infecciosas y/o prevención de transmisión de enfermedades infecciosas en equinos. La presente invención también se refiere a ácidos nucleicos que codifican tales moléculas iMAT, correspondiente vectores y células o líneas celulares primarias.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14162575 | 2014-03-31 | ||
PCT/EP2015/056670 WO2015150243A1 (en) | 2014-03-31 | 2015-03-27 | Improved modular antigen transportation molecules and uses therof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016012840A true MX2016012840A (es) | 2017-05-09 |
Family
ID=50433975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016012840A MX2016012840A (es) | 2014-03-31 | 2015-03-27 | Moléculas para transporte de antígeno modular mejoradas y sus usos. |
Country Status (12)
Country | Link |
---|---|
US (2) | US9920101B2 (es) |
EP (1) | EP3125933B1 (es) |
JP (1) | JP6370398B2 (es) |
KR (1) | KR20160138283A (es) |
CN (1) | CN106132996B (es) |
AR (1) | AR100310A1 (es) |
AU (1) | AU2015239770B2 (es) |
CA (1) | CA2943690A1 (es) |
EA (1) | EA034692B1 (es) |
MX (1) | MX2016012840A (es) |
TW (1) | TWI705823B (es) |
WO (1) | WO2015150243A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106132996B (zh) | 2014-03-31 | 2020-10-09 | 勃林格殷格翰动物保健有限公司 | 经改良的模块化抗原转运分子及其用途 |
US10898568B2 (en) | 2015-09-30 | 2021-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Modular antigen transportation molecules and uses thereof in animals |
US11547662B2 (en) | 2017-10-25 | 2023-01-10 | Allero Therapeutics B.V. | Treatment of immune diseases by administration of antigen-specific formulations |
US20220047648A1 (en) * | 2019-01-09 | 2022-02-17 | Md Healthcare Inc. | Nanovesicles derived from bacteria of genus rhodococcus, and use thereof |
CN110343160A (zh) * | 2019-07-26 | 2019-10-18 | 四川农业大学 | 黄粉虫ym47蛋白、其编码基因及应用 |
KR200491545Y1 (ko) | 2019-10-29 | 2020-04-24 | 김용호 | 맞춤형 기능성 베개 |
KR200494146Y1 (ko) | 2019-10-29 | 2021-08-12 | 김용호 | 맞춤형 기능성 베개 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5804604A (en) | 1989-12-21 | 1998-09-08 | Biogen, Inc. | Tat-derived transport polypeptides and fusion proteins |
US5633234A (en) | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
WO1994018999A1 (en) | 1993-02-26 | 1994-09-01 | Immtech International, Inc. | A mutant protein and methods and materials for making and using it |
GB9825421D0 (en) | 1998-11-19 | 1999-01-13 | Isis Innovation | Process for oxidising terpenes |
JP3993035B2 (ja) | 2001-07-19 | 2007-10-17 | 松下電器産業株式会社 | データ記録方法、記録媒体、および再生装置 |
EP1408114B1 (de) * | 2002-10-11 | 2007-01-03 | Imvision GmbH | Moduläre Antigen-Transporter Moleküle (MAT-Moleküle) zur Modulierung von Immunreaktionen, zugehörige Konstrukte, Verfahren und Verwendungen |
DK1440979T3 (da) * | 2003-01-21 | 2005-12-19 | Biomay Prod & Handel | Fremgangsmåde til fremstillingen af hypoallergene mosaikproteiner |
US20090117136A1 (en) | 2003-04-24 | 2009-05-07 | Imvision Gmbh | Recombinant allergen |
ATE461278T1 (de) | 2003-05-07 | 2010-04-15 | Chemo Sero Therapeut Res Inst | Verfahren zur reinigung des modifizierten hauptallergens von milben |
DE10359351A1 (de) * | 2003-12-16 | 2005-07-21 | Merck Patent Gmbh | DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden |
WO2007065633A1 (en) | 2005-12-05 | 2007-06-14 | Imvision Ag | Modulation of the immune response by administration of intralymphatic transduction allergen (itag) -molecules |
CN101820907B (zh) | 2007-08-15 | 2013-05-01 | 切尔卡西亚有限公司 | 针对过敏原去敏化的肽 |
UY31930A (es) * | 2008-06-25 | 2010-01-29 | Boheringer Ingelheim Pharma Kg | Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante |
JP2011212008A (ja) * | 2010-03-16 | 2011-10-27 | Olympus Corp | 蛍光タンパク質およびpH測定方法 |
WO2012121395A1 (ja) * | 2011-03-09 | 2012-09-13 | 国立大学法人徳島大学 | コレステロール依存性細胞溶解毒素の変異体及びそのddsへの利用 |
US9546200B2 (en) | 2011-06-09 | 2017-01-17 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Peptide for protection of allergic respiratory disorders |
CN106132996B (zh) | 2014-03-31 | 2020-10-09 | 勃林格殷格翰动物保健有限公司 | 经改良的模块化抗原转运分子及其用途 |
US10898568B2 (en) | 2015-09-30 | 2021-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Modular antigen transportation molecules and uses thereof in animals |
CN107389010A (zh) * | 2017-07-25 | 2017-11-24 | 爱佩仪中测(成都)精密仪器有限公司 | 提高三维测量仪器测量精度的支撑机构 |
-
2015
- 2015-03-27 CN CN201580016624.5A patent/CN106132996B/zh not_active Expired - Fee Related
- 2015-03-27 US US14/670,670 patent/US9920101B2/en active Active
- 2015-03-27 JP JP2016557146A patent/JP6370398B2/ja not_active Expired - Fee Related
- 2015-03-27 KR KR1020167030413A patent/KR20160138283A/ko not_active Application Discontinuation
- 2015-03-27 EP EP15741850.0A patent/EP3125933B1/en active Active
- 2015-03-27 MX MX2016012840A patent/MX2016012840A/es active IP Right Grant
- 2015-03-27 CA CA2943690A patent/CA2943690A1/en not_active Abandoned
- 2015-03-27 WO PCT/EP2015/056670 patent/WO2015150243A1/en active Application Filing
- 2015-03-27 AU AU2015239770A patent/AU2015239770B2/en not_active Ceased
- 2015-03-27 EA EA201691981A patent/EA034692B1/ru not_active IP Right Cessation
- 2015-03-30 TW TW104110343A patent/TWI705823B/zh not_active IP Right Cessation
- 2015-03-31 AR ARP150100974A patent/AR100310A1/es unknown
-
2018
- 2018-01-29 US US15/882,455 patent/US10919945B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN106132996B (zh) | 2020-10-09 |
EA034692B1 (ru) | 2020-03-06 |
US9920101B2 (en) | 2018-03-20 |
AU2015239770B2 (en) | 2020-07-02 |
EP3125933B1 (en) | 2022-05-18 |
TWI705823B (zh) | 2020-10-01 |
US20180170978A1 (en) | 2018-06-21 |
CN106132996A (zh) | 2016-11-16 |
US20150274790A1 (en) | 2015-10-01 |
WO2015150243A1 (en) | 2015-10-08 |
US10919945B2 (en) | 2021-02-16 |
EP3125933A1 (en) | 2017-02-08 |
JP6370398B2 (ja) | 2018-08-08 |
CA2943690A1 (en) | 2015-10-08 |
EA201691981A1 (ru) | 2017-03-31 |
KR20160138283A (ko) | 2016-12-02 |
JP2017510268A (ja) | 2017-04-13 |
AR100310A1 (es) | 2016-09-28 |
AU2015239770A1 (en) | 2016-08-04 |
TW201607554A (zh) | 2016-03-01 |
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Legal Events
Date | Code | Title | Description |
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HH | Correction or change in general | ||
FG | Grant or registration |