MX2016011902A - Medicamentos de administracion nasal y metodos para su uso. - Google Patents
Medicamentos de administracion nasal y metodos para su uso.Info
- Publication number
- MX2016011902A MX2016011902A MX2016011902A MX2016011902A MX2016011902A MX 2016011902 A MX2016011902 A MX 2016011902A MX 2016011902 A MX2016011902 A MX 2016011902A MX 2016011902 A MX2016011902 A MX 2016011902A MX 2016011902 A MX2016011902 A MX 2016011902A
- Authority
- MX
- Mexico
- Prior art keywords
- drug products
- methods
- nasal drug
- nasal
- symptoms
- Prior art date
Links
- 229940126534 drug product Drugs 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 208000012488 Opiate Overdose Diseases 0.000 abstract 1
- 229940123257 Opioid receptor antagonist Drugs 0.000 abstract 1
- 239000003401 opiate antagonist Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
- A61M11/08—Pocket atomisers of the injector type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Otolaryngology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Mechanical Engineering (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Se proporcionan medicamentos adaptados para su administración por vía nasal, que comprenden un dispositivo pre-cebado y cargado con una composición farmacéutica que comprende a un antagonista de receptores opioides. También se proporcionan métodos de tratamiento de sobredosis con opiáceos o sus síntomas con los medicamentos inventivos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953379P | 2014-03-14 | 2014-03-14 | |
| PCT/IB2015/000941 WO2015136373A1 (en) | 2014-03-14 | 2015-03-16 | Nasal drug products and methods of their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016011902A true MX2016011902A (es) | 2017-05-12 |
| MX365383B MX365383B (es) | 2019-05-31 |
Family
ID=53719795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016011902A MX365383B (es) | 2014-03-14 | 2015-03-16 | Medicamentos de administracion nasal y metodos para su uso. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9211253B2 (es) |
| EP (2) | EP3777838A1 (es) |
| JP (3) | JP2017508800A (es) |
| CN (2) | CN110755372A (es) |
| AU (1) | AU2015228541B2 (es) |
| CA (1) | CA2942611C (es) |
| DE (1) | DE112015001251T5 (es) |
| ES (1) | ES2631504B1 (es) |
| GB (1) | GB2538682B (es) |
| HK (1) | HK1231370A1 (es) |
| IL (3) | IL247742A0 (es) |
| MX (1) | MX365383B (es) |
| RU (2) | RU2016136714A (es) |
| SG (2) | SG11201607281PA (es) |
| WO (1) | WO2015136373A1 (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY194947A (en) | 2011-05-13 | 2022-12-27 | Euro Celtique Sa | Intranasal pharmaceutical dosage forms comprising naloxone |
| US9192570B2 (en) | 2013-12-20 | 2015-11-24 | AntiOP, Inc. | Intranasal naloxone compositions and methods of making and using same |
| HK1231370A1 (zh) | 2014-03-14 | 2017-12-22 | 欧皮安特制药有限公司 | 鼻用药物产品及其使用方法 |
| US9561177B2 (en) | 2014-03-14 | 2017-02-07 | Adapt Pharma Limited | Nasal drug products and methods of their use |
| US9480644B2 (en) | 2014-03-14 | 2016-11-01 | Opiant Pharmaceuticals, Inc. | Nasal drug products and methods of their use |
| US10085937B2 (en) | 2014-03-14 | 2018-10-02 | Adapt Pharma Limited | Nasal drug products and methods of their use |
| CA2954370A1 (en) * | 2014-07-08 | 2016-01-14 | Insys Pharma, Inc. | Sublingual naloxone spray |
| US11135155B2 (en) * | 2014-07-08 | 2021-10-05 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
| WO2017049181A1 (en) * | 2015-09-17 | 2017-03-23 | Adapt Pharma Limited | Nasal drug products and methods of their use |
| US10940274B2 (en) | 2015-12-01 | 2021-03-09 | Cipla Limited | Nasal spray assembly |
| JP7114570B2 (ja) * | 2016-08-17 | 2022-08-08 | ヒクマ・ファーマシューティカルズ・ユー・エス・エイ・インコーポレイテッド | 液体ナロキソンスプレー |
| WO2018064672A1 (en) * | 2016-09-30 | 2018-04-05 | Opiant Pharmaceuticals, Inc. | Treatment with intranasal naloxone |
| CN110139651A (zh) * | 2016-11-18 | 2019-08-16 | 欧邦特制药公司 | 用于治疗阿片样物质过量的组合物和方法 |
| US20180174261A1 (en) * | 2016-12-20 | 2018-06-21 | Adapt Pharma Operations Limited | Systems, devices, & methods for locating opioid antagonist products |
| WO2018130948A1 (en) * | 2017-01-11 | 2018-07-19 | Torrent Pharmaceuticals Limited | Tapentadol nasal composition |
| US11844859B2 (en) | 2017-08-20 | 2023-12-19 | Nasus Pharma Ltd. | Dry powder compositions for intranasal delivery |
| US11331270B2 (en) | 2017-08-20 | 2022-05-17 | Nasus Pharma Ltd. | Dry powder compositions for intranasal delivery |
| US20180193332A1 (en) * | 2017-10-09 | 2018-07-12 | Adapt Pharma Operations Limited | Low-temperature stable opioid antagonist solutions |
| WO2020033402A1 (en) * | 2018-08-06 | 2020-02-13 | Summit Biosciences Inc. | Drug products for nasal administration and uses thereof |
| AU2019403368A1 (en) * | 2018-12-20 | 2021-07-29 | Aegis Therapeutics, Llc | Compositions, devices, and methods for the treatment of overdose and reward-based disorders |
| CN111346078B (zh) * | 2018-12-21 | 2022-06-10 | 宜昌人福药业有限责任公司 | 一种他喷他多或其药学上可接受的盐经鼻粘膜给药的药物组合物及其制备方法和应用 |
| EP3946547B1 (en) | 2019-03-26 | 2026-03-25 | Pinova Therapeutics Inc. | Devices and methods for delivering pharmaceutical compositions |
| CA3166250A1 (en) | 2020-02-05 | 2021-08-12 | Gregory G. Plucinski | Drug products for intranasal administration and uses thereof |
| US20210330903A1 (en) * | 2020-04-28 | 2021-10-28 | Navinta Iii Inc | Multiple Dose Nasal Spray of Naloxone |
| WO2021225973A1 (en) * | 2020-05-04 | 2021-11-11 | Amphastar Pharmaceuticals, Inc. | Naloxone pharmaceutical formulations for intranasal (in) delivery |
| US11278709B1 (en) | 2021-03-12 | 2022-03-22 | Pocket Naloxone Corp. | Drug delivery device and methods for using same |
| AU2022323269A1 (en) | 2021-08-04 | 2024-02-29 | Indivior Inc. | Compositions and methods for the treatment of opioid overdose |
| US20240131022A1 (en) * | 2022-03-11 | 2024-04-25 | John Abernethy | Opioid overdose reversal mixtures |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181726A (en) | 1978-11-16 | 1980-01-01 | Bernstein Joel E | Method of alleviating pruritis |
| US4464378A (en) | 1981-04-28 | 1984-08-07 | University Of Kentucky Research Foundation | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
| US4987136A (en) | 1982-03-16 | 1991-01-22 | The Rockefeller University | Method for controlling gastrointestinal dysmotility |
| US5866154A (en) | 1994-10-07 | 1999-02-02 | The Dupont Merck Pharmaceutical Company | Stabilized naloxone formulations |
| US5908825A (en) | 1997-01-09 | 1999-06-01 | University Of Maryland At Baltimore | Dosage composition for nasal delivery and method of use of the same |
| AU4459700A (en) * | 1999-04-19 | 2000-11-02 | Millipore Corporation | Modular surface mount mass flow and pressure controller |
| GB9908921D0 (en) * | 1999-04-19 | 1999-06-16 | Britannia Pharmaceuticals Ltd | Spray dispenser for opiod antagonists |
| AU5072000A (en) | 1999-06-02 | 2000-12-28 | Hexal Ag | Pharmaceutical composition for nasally administering water-soluble active substances |
| EP2092936B1 (en) | 2000-02-08 | 2013-03-20 | Euro-Celtique S.A. | Tamper-resistant oral opioid agonist formulations |
| US6284765B1 (en) | 2000-04-27 | 2001-09-04 | The University Of North Texas Health Science Center At Fort Worth | (+) naloxone and epinephrine combination therapy |
| AU2001262992A1 (en) | 2000-05-10 | 2002-02-18 | University Of Kentucky Research Foundation | System and method for intranasal administration of opioids |
| US20040115133A1 (en) | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
| US6583039B2 (en) | 2001-10-15 | 2003-06-24 | Taiwan Semiconductor Manufacturing Co., Ltd. | Method of forming a bump on a copper pad |
| HUE032656T2 (en) | 2002-04-05 | 2017-10-30 | Euro Celtique Sa | Pharmaceutical composition containing oxicodone and naloxone |
| WO2004054511A2 (en) | 2002-12-13 | 2004-07-01 | The Regents Of The University Of California | Analgesic combination comprising nalbuphine |
| CN1575795A (zh) | 2003-06-25 | 2005-02-09 | 中国人民解放军军事医学科学院毒物药物研究所 | 盐酸纳洛酮鼻腔喷雾剂 |
| CN1726915B (zh) * | 2004-07-27 | 2013-04-24 | 中国人民解放军军事医学科学院毒物药物研究所 | 盐酸纳洛酮鼻腔给药系统或组合物及其制备方法 |
| WO2006016530A1 (ja) * | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
| US20060120967A1 (en) | 2004-12-07 | 2006-06-08 | Qpharma, Llc | Solution forms of cyclodextrins for nasal or throat delivery of essential oils |
| US7910599B2 (en) | 2005-01-10 | 2011-03-22 | John David Sinclair | Method for treating eating disorders by selective extinction with transdermal naloxone |
| EP1695700A1 (en) | 2005-02-28 | 2006-08-30 | Euro-Celtique S.A. | Dosage form containing oxycodone and naloxone |
| AU2006335994A1 (en) * | 2006-01-19 | 2007-07-26 | Optinose As | Nasal administration |
| US20070212307A1 (en) | 2006-02-10 | 2007-09-13 | Daniel Wermeling | Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same |
| CN101668544B (zh) * | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
| GB2447015A (en) | 2007-03-01 | 2008-09-03 | Reckitt Benckiser Healthcare | Analgesic composition comprising a specific ratio of buprenorphine and naltrexone |
| GB2447016A (en) | 2007-03-01 | 2008-09-03 | Reckitt Benckiser Healthcare | Buprenorphine/naloxone compositions |
| WO2009040595A1 (en) * | 2007-09-28 | 2009-04-02 | Wockhardt Research Centre | Multi-dose pharmaceutical composition of analgesic for nasal administration |
| WO2012026963A2 (en) | 2010-08-23 | 2012-03-01 | Darren Rubin | Systems and methods of aerosol delivery with airflow regulation |
| MY194947A (en) * | 2011-05-13 | 2022-12-27 | Euro Celtique Sa | Intranasal pharmaceutical dosage forms comprising naloxone |
| US10549052B2 (en) | 2012-02-28 | 2020-02-04 | Sipnose Ltd. | Nasal delivery device |
| US20150231130A1 (en) * | 2012-07-26 | 2015-08-20 | Wockhardt Limited | Pharmaceutical composition comprising diamorphine for intranasal administration |
| US9192570B2 (en) | 2013-12-20 | 2015-11-24 | AntiOP, Inc. | Intranasal naloxone compositions and methods of making and using same |
| HK1231370A1 (zh) | 2014-03-14 | 2017-12-22 | 欧皮安特制药有限公司 | 鼻用药物产品及其使用方法 |
| US20160008277A1 (en) * | 2014-07-09 | 2016-01-14 | Lightlake Therapeutics Inc. | Co-packaged drug products |
-
2015
- 2015-03-16 HK HK17104937.9A patent/HK1231370A1/zh unknown
- 2015-03-16 DE DE112015001251.6T patent/DE112015001251T5/de active Pending
- 2015-03-16 SG SG11201607281PA patent/SG11201607281PA/en unknown
- 2015-03-16 SG SG10202003562WA patent/SG10202003562WA/en unknown
- 2015-03-16 US US14/659,472 patent/US9211253B2/en active Active
- 2015-03-16 CN CN201911075872.3A patent/CN110755372A/zh active Pending
- 2015-03-16 JP JP2016574513A patent/JP2017508800A/ja active Pending
- 2015-03-16 WO PCT/IB2015/000941 patent/WO2015136373A1/en not_active Ceased
- 2015-03-16 RU RU2016136714A patent/RU2016136714A/ru not_active Application Discontinuation
- 2015-03-16 CA CA2942611A patent/CA2942611C/en active Active
- 2015-03-16 EP EP20197668.5A patent/EP3777838A1/en not_active Withdrawn
- 2015-03-16 GB GB1616616.7A patent/GB2538682B/en active Active
- 2015-03-16 CN CN201580018614.5A patent/CN106163499A/zh active Pending
- 2015-03-16 AU AU2015228541A patent/AU2015228541B2/en active Active
- 2015-03-16 RU RU2020112530A patent/RU2020112530A/ru unknown
- 2015-03-16 ES ES201690046A patent/ES2631504B1/es active Active
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2016
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|---|---|
| GB2538682B (en) | 2017-12-13 |
| CN110755372A (zh) | 2020-02-07 |
| HK1231370A1 (zh) | 2017-12-22 |
| RU2016136714A3 (es) | 2018-10-10 |
| JP2019189631A (ja) | 2019-10-31 |
| US20150258019A1 (en) | 2015-09-17 |
| CA2942611C (en) | 2017-10-10 |
| US9211253B2 (en) | 2015-12-15 |
| CA2942611A1 (en) | 2015-09-17 |
| SG11201607281PA (en) | 2016-09-29 |
| IL279001A (en) | 2021-01-31 |
| EP3116478A1 (en) | 2017-01-18 |
| ES2631504R1 (es) | 2017-12-11 |
| AU2015228541A1 (en) | 2016-09-29 |
| CN106163499A (zh) | 2016-11-23 |
| IL247742A0 (en) | 2016-11-30 |
| ES2631504A2 (es) | 2017-08-31 |
| MX365383B (es) | 2019-05-31 |
| GB201616616D0 (en) | 2016-11-16 |
| IL272294A (en) | 2020-02-27 |
| RU2020112530A (ru) | 2021-07-21 |
| WO2015136373A1 (en) | 2015-09-17 |
| SG10202003562WA (en) | 2020-05-28 |
| EP3777838A1 (en) | 2021-02-17 |
| JP2017508800A (ja) | 2017-03-30 |
| JP2021046408A (ja) | 2021-03-25 |
| ES2631504B1 (es) | 2018-11-28 |
| AU2015228541B2 (en) | 2020-09-03 |
| DE112015001251T5 (de) | 2017-01-19 |
| RU2016136714A (ru) | 2018-04-19 |
| GB2538682A (en) | 2016-11-23 |
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