MX2016010604A - Compuestos de dominio de unión a ácido desoxirribonucleico (dbd a adn) del receptor de andrógeno humano como terapéuticos, y métodos para su uso. - Google Patents

Compuestos de dominio de unión a ácido desoxirribonucleico (dbd a adn) del receptor de andrógeno humano como terapéuticos, y métodos para su uso.

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Publication number
MX2016010604A
MX2016010604A MX2016010604A MX2016010604A MX2016010604A MX 2016010604 A MX2016010604 A MX 2016010604A MX 2016010604 A MX2016010604 A MX 2016010604A MX 2016010604 A MX2016010604 A MX 2016010604A MX 2016010604 A MX2016010604 A MX 2016010604A
Authority
MX
Mexico
Prior art keywords
compounds
substituted
heteroaryl
dbd
therapeutics
Prior art date
Application number
MX2016010604A
Other languages
English (en)
Spanish (es)
Inventor
Tcherkassov Artem
S Rennie Paul
Ban Fuqiang
Li Huifang
Joseph Jean Leblanc Eric
Dalal Kush
V Tverdokhlebov Anton
Babiy Sergiy
BOGOMOL Evgeniia
DUNAYENKO Kateryna
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of MX2016010604A publication Critical patent/MX2016010604A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
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