JP2017505787A - 治療薬としてのヒトアンドロゲン受容体dna結合ドメイン(dbd)化合物およびそれらを使用する方法 - Google Patents
治療薬としてのヒトアンドロゲン受容体dna結合ドメイン(dbd)化合物およびそれらを使用する方法 Download PDFInfo
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- JP2017505787A JP2017505787A JP2016551163A JP2016551163A JP2017505787A JP 2017505787 A JP2017505787 A JP 2017505787A JP 2016551163 A JP2016551163 A JP 2016551163A JP 2016551163 A JP2016551163 A JP 2016551163A JP 2017505787 A JP2017505787 A JP 2017505787A
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- 0 Nc(c(N)c1*2)ccc1N=C2*1CCOCC1 Chemical compound Nc(c(N)c1*2)ccc1N=C2*1CCOCC1 0.000 description 7
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- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461940275P | 2014-02-14 | 2014-02-14 | |
| US61/940,275 | 2014-02-14 | ||
| US201462023773P | 2014-07-11 | 2014-07-11 | |
| US62/023,773 | 2014-07-11 | ||
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| JP2022523916A (ja) * | 2019-01-30 | 2022-04-27 | モンテリノ・セラピューティクス・インコーポレイテッド | アンドロゲン受容体を標的とするユビキチン化のための二官能性化合物および方法 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022504296A (ja) * | 2018-10-03 | 2022-01-13 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | 治療薬としての転写因子brn2阻害化合物およびそれらの使用方法 |
| JP2022523916A (ja) * | 2019-01-30 | 2022-04-27 | モンテリノ・セラピューティクス・インコーポレイテッド | アンドロゲン受容体を標的とするユビキチン化のための二官能性化合物および方法 |
| JP7555938B2 (ja) | 2019-01-30 | 2024-09-25 | モンテリノ・セラピューティクス・インコーポレイテッド | アンドロゲン受容体を標的とするユビキチン化のための二官能性化合物および方法 |
| JP2022547707A (ja) * | 2019-09-12 | 2022-11-15 | ディスアーム セラピューティクス, インコーポレイテッド | Sarm1の阻害剤 |
| JP7534390B2 (ja) | 2019-09-12 | 2024-08-14 | ディスアーム セラピューティクス, インコーポレイテッド | Sarm1の阻害剤 |
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|---|---|
| US20170183319A1 (en) | 2017-06-29 |
| MX2016010604A (es) | 2017-04-27 |
| JP2019142880A (ja) | 2019-08-29 |
| CN106164071B (zh) | 2019-09-10 |
| WO2015120543A1 (en) | 2015-08-20 |
| US10011573B2 (en) | 2018-07-03 |
| AU2015218140A1 (en) | 2016-09-01 |
| RU2016136091A (ru) | 2018-03-19 |
| CA2939048A1 (en) | 2015-08-20 |
| CN106164071A (zh) | 2016-11-23 |
| KR20160115999A (ko) | 2016-10-06 |
| EP3105229A1 (en) | 2016-12-21 |
| EP3105229A4 (en) | 2017-12-20 |
| BR112016018691A2 (pt) | 2017-08-08 |
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