MX2016008305A - Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo. - Google Patents

Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo.

Info

Publication number
MX2016008305A
MX2016008305A MX2016008305A MX2016008305A MX2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A MX 2016008305 A MX2016008305 A MX 2016008305A
Authority
MX
Mexico
Prior art keywords
dust mite
der
peptide combinations
peptides
mite allergy
Prior art date
Application number
MX2016008305A
Other languages
English (en)
Inventor
Sette Alessandro
Lundegaard Claus
Harder CHRISTENSEN Lars
Adler WÜRTZEN Peter
Sidney John
Lund Gitte
Original Assignee
Alk-Abelló As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alk-Abelló As filed Critical Alk-Abelló As
Publication of MX2016008305A publication Critical patent/MX2016008305A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se relaciona a combinaciones de péptidos o variantes de los mismos derivados de una porción de una secuencia de amino de un alérgeno de ácaro del polvo doméstico, por ejemplo los alérgenos Der p 1, Der f 1, Der p 2 y/o Der f 2. Tales péptidos comprenden al menos un epítopo de célula T y un número elevado significativo de pacientes en una población mundial tendrán alelos HLA con el potencial de ligar los péptidos de las combinaciones de péptidos. La invención también se relaciona al uso de tales combinaciones de péptidos en aliviar una respuesta inmunitaria causada por un ácaro del polvo.
MX2016008305A 2013-12-23 2014-12-23 Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo. MX2016008305A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361919925P 2013-12-23 2013-12-23
US201462012690P 2014-06-16 2014-06-16
PCT/US2014/072228 WO2015100360A1 (en) 2013-12-23 2014-12-23 Peptide combinations and uses thereof in treating dust mite allergy

Publications (1)

Publication Number Publication Date
MX2016008305A true MX2016008305A (es) 2017-01-11

Family

ID=52293308

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016008305A MX2016008305A (es) 2013-12-23 2014-12-23 Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo.

Country Status (12)

Country Link
US (1) US10059751B2 (es)
EP (1) EP3086806B1 (es)
JP (1) JP2017507906A (es)
KR (1) KR20160096206A (es)
CN (1) CN105848677B (es)
AU (1) AU2014369866A1 (es)
BR (1) BR112016011930A2 (es)
CA (1) CA2933552A1 (es)
EA (1) EA201691306A1 (es)
MX (1) MX2016008305A (es)
SG (1) SG11201604892YA (es)
WO (1) WO2015100360A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9265824B2 (en) * 2010-06-03 2016-02-23 Alk-Abello A/S Pharmaceutical product comprising mite allergen extract(s) and a method for the manufacture thereof
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
WO2017096247A1 (en) * 2015-12-04 2017-06-08 Mayo Foundation For Medical Education And Research Methods and vaccines for inducing immune responses to multiple different mhc molecules
WO2017203057A1 (en) * 2016-05-27 2017-11-30 Alk-Abelló A/S Immunogenic proteins and fragments thereof from allergenic mites
CN108265059B (zh) 2016-12-31 2021-01-05 江苏众红生物工程创药研究院有限公司 一种重组粉尘螨2类变应原蛋白及其制备方法与应用
CN107338261B (zh) * 2017-07-17 2023-04-07 海南大学 热带无爪螨重组变应原Blot5-21、其制备方法及过敏小鼠模型的建立
BR112021018211A2 (pt) * 2019-03-14 2021-11-23 Engene Inc Revestimento reversível de nanopartículas de quitosana-ácido nucléico e métodos de seu uso
CN113125753B (zh) * 2021-04-16 2022-07-26 杭州浙大迪迅生物基因工程有限公司 一种用于检测尘螨组分特异性抗体的试剂盒
KR102927988B1 (ko) 2023-03-17 2026-02-23 가톨릭대학교 산학협력단 집먼지진드기 항원 및 히알루론산 하이드로젤을 유효성분으로 포함하는 알레르기 질환 면역 치료용 조성물
GB202409214D0 (en) * 2024-06-26 2024-08-07 Univ Birmingham tolerogenic peptides
CN120559260A (zh) * 2025-07-30 2025-08-29 无锡市人民医院 过敏原Blo t 24在尘螨过敏原组分检测中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US7288256B1 (en) * 1991-10-16 2007-10-30 Merck Patent Gmbh T cell epitopes of the major allergens from dermatophagoides (house dust mite)
EP0610335B1 (en) 1991-10-16 2008-01-02 Merck Patent GmbH Methods for designing recombitope peptides
WO1994024281A1 (en) 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
ES2285703T3 (es) 1994-04-14 2007-11-16 Merck Patent Gmbh Formulaciones farmaceuticas de peptidos para el tratamiento de alergia a los acaros del polvo.
US5820862A (en) * 1994-04-14 1998-10-13 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
JP2001231563A (ja) 2000-02-18 2001-08-28 Asahi Breweries Ltd 改変したダニアレルゲン（システイン変異体）及びその製造方法
CA2546443A1 (en) 2003-11-18 2005-06-02 Nanopass Technologies Ltd. Enhanced penetration system and method for sliding microneedles
CA2587216C (en) 2004-11-18 2014-11-18 Nanopass Technologies Ltd. System and method for delivering fluid into flexible biological barrier
JP2010512170A (ja) 2005-12-08 2010-04-22 ナノパス テクノロジーズ エルティディ． 薬剤投与器用マイクロ・ニードル・アダプタ
JP5750600B2 (ja) * 2006-08-11 2015-07-22 ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルクＬｉｆｅ Ｓｃｉｅｎｃｅｓ Ｒｅｓｅａｒｃｈ Ｐａｒｔｎｅｒｓ Ｖｚｗ 免疫原性ペプチドおよび免疫障害におけるその使用
DK2083856T3 (da) * 2007-08-15 2011-01-24 Circassia Ltd Peptider til desensibilisering mod allergener
WO2010018384A1 (en) 2008-08-15 2010-02-18 Circassia Limited T-cell antigen peptide from allergen for stimulation of il-10 production
EP2717910B1 (en) 2011-06-09 2019-01-23 Biomay Ag Peptide carrier fusion proteins as allergy vaccines
US20130110043A1 (en) 2011-10-26 2013-05-02 Nanopass Technologies Ltd. Microneedle Intradermal Drug Delivery Device with Auto-Disable Functionality
WO2013119853A1 (en) * 2012-02-07 2013-08-15 La Jolla Institute For Allergy And Immunology Epitopes from allergen proteins and methods and uses for immune response modulation
CN104203277A (zh) 2012-02-07 2014-12-10 拉霍拉敏感及免疫学研究所 梯牧草变应原和用于调节免疫反应的方法和用途
US20130302338A1 (en) 2012-05-14 2013-11-14 Promd Biotech. Co., Ltd. Dermatophagoid pteronyssinus (der p1) antigen epitope and anti-der p1 antibody
US20140350514A1 (en) 2013-05-22 2014-11-27 Nanopass Technologies Ltd. Systems and methods for intradermal delivery of therapeutics using microneedles

Also Published As

Publication number Publication date
EP3086806A1 (en) 2016-11-02
BR112016011930A2 (pt) 2017-09-26
SG11201604892YA (en) 2016-07-28
CA2933552A1 (en) 2015-07-02
CN105848677A (zh) 2016-08-10
CN105848677B (zh) 2020-01-31
AU2014369866A1 (en) 2016-06-30
WO2015100360A1 (en) 2015-07-02
JP2017507906A (ja) 2017-03-23
EA201691306A1 (ru) 2016-10-31
US20160251403A1 (en) 2016-09-01
US10059751B2 (en) 2018-08-28
KR20160096206A (ko) 2016-08-12
EP3086806B1 (en) 2019-12-11

Similar Documents

Publication Publication Date Title
MX2016008305A (es) Combinaciones de peptidos y usos de los mismos en tratar alergia al acaro del polvo.
MX2025009589A (es) Vacunas a base de peptidos, metodos de fabricacion y sus usos para inducir una respuesta inmune
ZA201805295B (en) Methods for enhancing efficacy of a vaccine by administering an il¿4r antagonist
WO2014113490A3 (en) Immunogenic wt-1 peptides and methods of use thereof
TN2017000085A1 (en) Polypeptide having a polyester degrading activity and uses thereof
MY201207A (en) Chimeric receptors to flt3 and methods of use thereof
NZ715038A (en) T cell receptors
MX2021012014A (es) Vectores del factor viii del virus adeno-asociado.
MX373035B (es) Trastornos neurodegenerativos.
MX364952B (es) Particula tipo virus que comprende antigeno de muerte celular programada 1 o antigeno de ligando de muerte celular programada 1.
MX2012002357A (es) Composiciones que inducen la ayuda de las celulas t.
GB201201511D0 (en) Modified epitopes for boosting CD4+ T-cell responses
MX385670B (es) Anticuerpos anti-garp-tgf-b.
MX2018014716A (es) Anticuerpos anti-tnfrsf25.
MX2014008146A (es) Constructos de mhc parciales y metodos de uso.
MX2016002214A (es) Gen con resistencia a la oxidacion.
HK1223019A1 (zh) 用於治疗室内尘蟎过敏的连续重叠肽
IN2014DN08325A (es)
WO2016131000A3 (en) Tolerance therapeutic for treating polypeptide induced allergy
MX2016005507A (es) Matriz de elucion y usos de la misma.
MX2014013394A (es) Sal de clorhidrato de un peptido y su uso en combinacion con otros peptidos para inmunoterapia.
MX2011008179A (es) Peptidos para vacuna.
EP2552462A4 (en) CCN3 THERAPEUTIC PEPTIDES AND THEIR ANALOGS
PH12015501033A1 (en) Peptides
MX2020012569A (es) Moleculas inmunoterapeuticas novedosas y sus usos.