MX2016007109A - Proteina estructurante de hielo. - Google Patents
Proteina estructurante de hielo.Info
- Publication number
- MX2016007109A MX2016007109A MX2016007109A MX2016007109A MX2016007109A MX 2016007109 A MX2016007109 A MX 2016007109A MX 2016007109 A MX2016007109 A MX 2016007109A MX 2016007109 A MX2016007109 A MX 2016007109A MX 2016007109 A MX2016007109 A MX 2016007109A
- Authority
- MX
- Mexico
- Prior art keywords
- sequence
- isp
- nucleic acid
- structuring protein
- ice structuring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/32—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds
- A23G9/38—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se relaciona con una construcción de ácido nucleico que comprende: una secuencia de ácidos nucleicos que codifica una proteína estructurante de hielo (ISP) que comprende la secuencia establecida en la SEQ ID NO: 1 o una secuencia por lo menos 80% idéntica a esta o que comprende la secuencia establecida en los aminoácidos 21 a 261 de la SEQ ID NO: 1 o una secuencia por lo menos 80% idéntica a esta; y, ligada operablemente a esta, las secuencias de control permiten la expresión de la secuencia de ácidos nucleicos en una célula anfitriona de hongo filamentoso. La construcción se puede utilizar en un método para la producción de un ISP, en donde el ISP se expresa en una célula anfitriona de hongo filamento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13195351 | 2013-12-02 | ||
| PCT/EP2014/076291 WO2015082488A1 (en) | 2013-12-02 | 2014-12-02 | Ice structuring protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016007109A true MX2016007109A (es) | 2016-09-08 |
| MX370305B MX370305B (es) | 2019-12-09 |
Family
ID=49679437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016007109A MX370305B (es) | 2013-12-02 | 2014-12-02 | Proteína estructurante de hielo. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10487125B2 (es) |
| EP (1) | EP3077517B1 (es) |
| CN (1) | CN105992822A (es) |
| DK (1) | DK3077517T3 (es) |
| ES (1) | ES2706742T3 (es) |
| MX (1) | MX370305B (es) |
| WO (1) | WO2015082488A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10487252B2 (en) * | 2018-01-24 | 2019-11-26 | Microtek Laboratories, Inc. | Water based thermal cooling gels comprising a viscosity modifier and ice nucleating protein |
| CN110428865B (zh) * | 2019-08-14 | 2021-08-20 | 信阳师范学院 | 一种高通量预测抗冻蛋白质的方法 |
| GB2618758B (en) * | 2021-01-31 | 2025-06-04 | The Fynder Group Inc | Colloidal food products comprising filamentous fungal particles |
| CN113388009B (zh) * | 2021-05-18 | 2022-07-19 | 中国科学院福建物质结构研究所 | 一种标签蛋白及其编码基因、重组载体与应用 |
| CN113444159A (zh) * | 2021-06-18 | 2021-09-28 | 南京纽田科技有限公司 | 能表达冰冻蛋白的黑曲霉发酵菌种 |
| EP4577560A1 (en) | 2022-08-23 | 2025-07-02 | Unilever IP Holdings B.V. | Improvements in or relating to digestion of proteins |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| CA1341226C (en) | 1988-08-16 | 2001-05-01 | Wim Van Hartingsveldt | Gene replacement as a tool for the construction of aspergillus strains |
| JPH04505329A (ja) | 1989-05-10 | 1992-09-17 | ディーエヌエー プラント テクノロジー コーポレイション | 不凍化ポリペプチド |
| US5118792A (en) | 1989-05-10 | 1992-06-02 | Dna Plant Technology Corporation | Ice crystal growth suppression polypeptides and method of making |
| ES2198410T3 (es) | 1993-07-23 | 2004-02-01 | Dsm Ip Assets B.V. | Cepas recombinantes de hongos filamentosos libres de gen marcador de seleccion: un metodo para obtener dichas cepas y su utilizacion. |
| EP0777737B1 (en) | 1994-06-30 | 2005-05-04 | Novozymes Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein |
| PL324437A1 (en) | 1995-07-05 | 1998-05-25 | Unilever Nv | Expression of a peptide preventing freezee of oceanic fishes in an organism suitable for use in food industry and application thereof in articles of food |
| US6548285B1 (en) | 1995-08-03 | 2003-04-15 | Dsm N.V. | Polynucleotides encoding Aspergillus Niger and Penicillium Chrysogenum acetamidases and methods of use as selectable markers |
| US6432672B1 (en) | 1997-04-11 | 2002-08-13 | Gerardus Cornelis Maria Selten | Gene conversion as a tool for the construction of recombinant industrial filamentous fungi |
| DE69838106T2 (de) | 1997-12-22 | 2008-04-03 | Dsm Ip Assets B.V. | Expressionsklonierung in filamentösen pilzen |
| AU4025700A (en) | 1999-03-22 | 2000-10-09 | Novo Nordisk Biotech, Inc. | Promoters for expressing genes in a fungal cell |
| AU7288100A (en) | 1999-09-17 | 2001-04-24 | Dsm N.V. | Regulation of secondary metabolite production |
| JP2006516399A (ja) | 2003-02-05 | 2006-07-06 | デーエスエム アイピー アセッツ ベー. ヴェー. | ポリペプチドを製造するためのシュウ酸欠損Aspergillusniger菌株の使用 |
| BRPI0400822A (pt) * | 2003-12-10 | 2005-08-23 | Unilever Nv | Produto de confeitaria e unidade de varejo |
| CN101218348B (zh) | 2004-04-02 | 2014-07-30 | 帝斯曼知识产权资产管理有限公司 | 具有提高的同源重组效率的丝状真菌突变体 |
| EP2345726A3 (en) | 2004-04-16 | 2011-12-14 | DSM IP Assets B.V. | Fungal promoter for expressing a gene in a fungal cell |
| CA2568788A1 (en) | 2004-06-16 | 2005-12-29 | Dsm Ip Assets B.V. | Production of polypeptides by improved secretion |
| CN101094919B (zh) | 2004-10-12 | 2014-09-03 | 帝斯曼知识产权资产管理有限公司 | 在生产多肽的方法中有用的真菌转录活化因子 |
| US20080070277A1 (en) | 2004-10-15 | 2008-03-20 | Sagt Cornelis M J | Homologous Amds Genes as Selectable Marker |
| CN101107354B (zh) | 2005-01-24 | 2012-05-30 | 帝斯曼知识产权资产管理有限公司 | 用于在有丝真菌细胞中生产感兴趣化合物的方法 |
| JP2008531031A (ja) | 2005-03-01 | 2008-08-14 | ディーエスエム アイピー アセッツ ビー.ブイ. | 真菌細胞中で遺伝子を発現させるためのアスペルギルス(Aspergillus)プロモーター |
| US8202523B2 (en) * | 2005-09-22 | 2012-06-19 | ProSci, Inc. | Glycosylated polypeptides produced in yeast mutants and methods of use thereof |
| CN101454455A (zh) | 2005-11-29 | 2009-06-10 | 帝斯曼知识产权资产管理有限公司 | 在基因表达中有用的转录激活因子的dna结合位点 |
| JP5250850B2 (ja) | 2006-06-29 | 2013-07-31 | ディーエスエム アイピー アセッツ ビー.ブイ. | 改善されたポリペプチド発現を達成する方法 |
| CA2677568A1 (en) | 2007-02-15 | 2008-08-21 | Dsm Ip Assets B.V. | A recombinant host cell for the production of a compound of interest |
| KR101700711B1 (ko) | 2007-11-21 | 2017-01-31 | 로스킬드 유니베르시테트 | 얼음-결합 활성을 포함하는 폴리펩티드 |
| DK2406386T3 (en) | 2009-03-10 | 2019-04-23 | Dsm Ip Assets Bv | PROCEDURE FOR IMPROVING THE YIELD OF A POLYPEPTIME |
| CA2758404A1 (en) | 2009-04-22 | 2010-10-28 | Dsm Ip Assets B.V. | Process for the production of a recombinant polypeptide of interest |
| KR101048721B1 (ko) * | 2009-06-22 | 2011-07-14 | 한국해양연구원 | 루코스포리디움 속 미생물의 결빙방지 단백질 유전자, 그를 포함하는 재조합 벡터 및 그 유전자로 암호화된 단백질 |
| AU2010275672A1 (en) | 2009-07-22 | 2012-02-02 | Dsm Ip Assets B.V. | Improved host cell for the production of a compound of interest |
| EP2462156A1 (en) * | 2009-08-07 | 2012-06-13 | Novozymes A/S | Method of producing a sweet protein |
| AU2011273351A1 (en) | 2010-07-01 | 2013-01-17 | Dsm Ip Assets B.V. | A method for the production of a compound of interest |
| KR101300177B1 (ko) | 2011-05-13 | 2013-08-26 | 한국해양과학기술원 | 극지 효모 유래 결빙방지단백질의 대량 생산방법 |
| CN103648297B (zh) * | 2011-07-11 | 2016-10-05 | 荷兰联合利华有限公司 | 具有凝胶涂层的冷冻甜食 |
| WO2013135729A1 (en) | 2012-03-12 | 2013-09-19 | Dsm Ip Assets B.V. | Recombination system |
| EP2875120B1 (en) | 2012-07-19 | 2019-03-20 | DSM IP Assets B.V. | Amylase-deficient strain |
| CN105308171B (zh) | 2012-07-19 | 2019-03-08 | 帝斯曼知识产权资产管理有限公司 | Agse缺陷菌株 |
-
2014
- 2014-12-02 CN CN201480065622.0A patent/CN105992822A/zh not_active Withdrawn
- 2014-12-02 ES ES14843223T patent/ES2706742T3/es active Active
- 2014-12-02 DK DK14843223.0T patent/DK3077517T3/en active
- 2014-12-02 US US15/039,110 patent/US10487125B2/en not_active Expired - Fee Related
- 2014-12-02 WO PCT/EP2014/076291 patent/WO2015082488A1/en not_active Ceased
- 2014-12-02 EP EP14843223.0A patent/EP3077517B1/en not_active Not-in-force
- 2014-12-02 MX MX2016007109A patent/MX370305B/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US20170029476A1 (en) | 2017-02-02 |
| CN105992822A (zh) | 2016-10-05 |
| ES2706742T3 (es) | 2019-04-01 |
| DK3077517T3 (en) | 2019-02-11 |
| WO2015082488A1 (en) | 2015-06-11 |
| MX370305B (es) | 2019-12-09 |
| US10487125B2 (en) | 2019-11-26 |
| EP3077517A1 (en) | 2016-10-12 |
| EP3077517B1 (en) | 2018-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |