MX2015013380A - Inmunoterapia para cordoma a base de levadura. - Google Patents

Inmunoterapia para cordoma a base de levadura.

Info

Publication number
MX2015013380A
MX2015013380A MX2015013380A MX2015013380A MX2015013380A MX 2015013380 A MX2015013380 A MX 2015013380A MX 2015013380 A MX2015013380 A MX 2015013380A MX 2015013380 A MX2015013380 A MX 2015013380A MX 2015013380 A MX2015013380 A MX 2015013380A
Authority
MX
Mexico
Prior art keywords
chordoma
yeast
based immunotherapy
individual
relates
Prior art date
Application number
MX2015013380A
Other languages
English (en)
Inventor
Claudia Palena
David Apelian
Jeffrey Schlom
Timothy C Rodell
Original Assignee
Globeimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Globeimmune Inc filed Critical Globeimmune Inc
Publication of MX2015013380A publication Critical patent/MX2015013380A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)

Abstract

Una modalidad de la invención se refiere a un método para tratar cordoma en un individuo que tiene cordoma. El método incluye el paso de administrar a un individuo que tiene cordoma, una composición inmunoterapéutica que comprende: (a); y (b) un antígeno cancerígeno que comprende al menos un antígeno de Braquiuria. Otra modalidad de la invención se refiere al uso de una composición inmunoterapéutica que comprende un vehículo de levadura que comprende al menos un antígeno de Braquiuria para cordoma en un individuo que tiene cordoma. Aún otra modalidad de la invención se refiere al uso de una composición inmunoterapéutica que comprende un vehículo de levadura.
MX2015013380A 2013-03-19 2014-03-19 Inmunoterapia para cordoma a base de levadura. MX2015013380A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361803332P 2013-03-19 2013-03-19
PCT/US2014/031183 WO2014186047A1 (en) 2013-03-19 2014-03-19 Yeast-based immunotherapy for chordoma

Publications (1)

Publication Number Publication Date
MX2015013380A true MX2015013380A (es) 2016-01-08

Family

ID=51898771

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013380A MX2015013380A (es) 2013-03-19 2014-03-19 Inmunoterapia para cordoma a base de levadura.

Country Status (15)

Country Link
US (2) US10507235B2 (es)
EP (1) EP2976100B1 (es)
JP (1) JP6509808B2 (es)
KR (1) KR20150132867A (es)
CN (1) CN105228646B (es)
AU (1) AU2014265873B2 (es)
BR (1) BR112015023968A2 (es)
CA (1) CA2907560C (es)
HK (1) HK1216861A1 (es)
IL (1) IL241384B (es)
MX (1) MX2015013380A (es)
RU (1) RU2679806C2 (es)
SG (2) SG11201507328RA (es)
TW (2) TWI674108B (es)
WO (1) WO2014186047A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
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EP3051449A1 (de) * 2015-01-29 2016-08-03 Bayer Technology Services GmbH Computerimplementiertes Verfahren zur Erstellung eines Fermentationsmodels
TWI748957B (zh) * 2015-08-03 2021-12-11 美商環球免疫公司 經修飾之酵母-短尾畸型(Brachyury)免疫治療組合物
EP4137150A1 (en) 2015-08-03 2023-02-22 The United States of America, as represented by the Secretary, Department of Health and Human Services Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2486400B1 (fr) 1980-07-09 1986-05-30 Univablot Medicaments a base de levures ou de leurs extraits insolubles
NZ199722A (en) 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
US4775622A (en) 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
US5310654A (en) 1985-07-31 1994-05-10 The Board Of Trustees Of The Leland Stanford Junior University Method for determining virulence of Yersinia
US5234830A (en) 1988-02-03 1993-08-10 Suntory Limited DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region
IL95019A0 (en) 1989-08-09 1991-06-10 Mycogen Corp Process for encapsulation of biologicals
US5413914A (en) 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US5830463A (en) 1993-07-07 1998-11-03 University Technology Corporation Yeast-based delivery vehicles
US5858378A (en) 1996-05-02 1999-01-12 Galagen, Inc. Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen
US7175839B1 (en) 1997-10-10 2007-02-13 Meyer Pharmaceuticals Llc Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy
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US8153414B2 (en) 2000-04-06 2012-04-10 Allertein Therapeutics, Llc Microbial delivery system
AU2002225681A1 (en) 2000-11-15 2002-05-27 Globe Immune, Inc. Yeast-dentritic cell vaccines and uses thereof
US7439042B2 (en) 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
CN1938044B (zh) 2002-12-16 2011-12-28 全球免疫股份有限公司 用于免疫治疗的基于酵母的疫苗
US20060009404A1 (en) 2004-07-09 2006-01-12 Williams Jason R Tumor ablation in combination with pharmaceutical compositions
WO2007008780A2 (en) 2005-07-11 2007-01-18 Globeimmune, Inc. Compositions and methods for eliciting an immune response to escape mutants of targeted therapies
US20070172503A1 (en) 2005-12-13 2007-07-26 Mycologics,Inc. Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines
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EP2004666B1 (en) 2006-03-27 2014-09-03 Globeimmune, Inc. Ras mutation and compositions and methods related thereto
SG10201405420QA (en) 2007-02-02 2014-10-30 Globeimmune Inc Methods for producing yeast-based vaccines
EP2918598B1 (en) * 2007-02-28 2019-01-30 The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services Brachyury polypeptides and methods for use
WO2008115610A1 (en) 2007-03-19 2008-09-25 Globeimmune, Inc. Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer
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JP5745102B2 (ja) 2011-02-12 2015-07-08 グローブイミューン,インコーポレイテッド 慢性b型肝炎感染症のための酵母系免疫療法組成物
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EA030381B1 (ru) 2011-06-14 2018-07-31 Глоубиммьюн, Инк. Иммунотерапевтическая композиция, ее применения и способы лечения или профилактики инфекции, вызванной вирусом гепатита дельта
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TWI748957B (zh) 2015-08-03 2021-12-11 美商環球免疫公司 經修飾之酵母-短尾畸型(Brachyury)免疫治療組合物

Also Published As

Publication number Publication date
EP2976100A4 (en) 2016-10-19
SG10201707608QA (en) 2017-10-30
JP2016516081A (ja) 2016-06-02
WO2014186047A1 (en) 2014-11-20
AU2014265873B2 (en) 2019-01-17
TWI674108B (zh) 2019-10-11
SG11201507328RA (en) 2015-10-29
CA2907560C (en) 2021-12-07
EP2976100B1 (en) 2020-07-01
JP6509808B2 (ja) 2019-05-08
CN105228646A (zh) 2016-01-06
BR112015023968A2 (pt) 2017-08-22
TW201446261A (zh) 2014-12-16
TW201936206A (zh) 2019-09-16
HK1216861A1 (zh) 2016-12-09
EP2976100A1 (en) 2016-01-27
US20160271238A1 (en) 2016-09-22
CA2907560A1 (en) 2014-11-20
RU2679806C2 (ru) 2019-02-13
IL241384B (en) 2019-12-31
KR20150132867A (ko) 2015-11-26
RU2015144511A (ru) 2017-05-03
CN105228646B (zh) 2021-04-06
IL241384A0 (en) 2015-11-30
AU2014265873A1 (en) 2015-10-22
US20200046818A1 (en) 2020-02-13
WO2014186047A8 (en) 2015-01-15
US10507235B2 (en) 2019-12-17

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