MX2015011470A - Monotriflatos de isohexida y procesos para su sintesis. - Google Patents
Monotriflatos de isohexida y procesos para su sintesis.Info
- Publication number
- MX2015011470A MX2015011470A MX2015011470A MX2015011470A MX2015011470A MX 2015011470 A MX2015011470 A MX 2015011470A MX 2015011470 A MX2015011470 A MX 2015011470A MX 2015011470 A MX2015011470 A MX 2015011470A MX 2015011470 A MX2015011470 A MX 2015011470A
- Authority
- MX
- Mexico
- Prior art keywords
- isohexide
- monotriflates
- synthesis
- compounds
- monotriflate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Se describen compuestos que son monotriflatos de isohexida y un método para su preparación. El método implica hacer reaccionar una mezcla de una isohexida, un anhídrido trifluorometanosulfónico y ya sea 1) una base nucleófila o 2) una combinación de una base no nucleófila y un nucleófilo. Los compuestos que son monotriflatos de isohexida pueden servir de materiales precursores a partir de los cuales se pueden sintetizar diversos compuestos derivados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361772637P | 2013-03-05 | 2013-03-05 | |
PCT/US2014/016758 WO2014137576A1 (en) | 2013-03-05 | 2014-02-18 | Isohexide monotriflates and process for synthesis thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015011470A true MX2015011470A (es) | 2016-06-15 |
Family
ID=51491771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015011470A MX2015011470A (es) | 2013-03-05 | 2014-02-18 | Monotriflatos de isohexida y procesos para su sintesis. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20160016969A1 (es) |
EP (1) | EP2964653A4 (es) |
JP (1) | JP2016510740A (es) |
KR (1) | KR20150123324A (es) |
CN (1) | CN105026402A (es) |
AU (1) | AU2014226533A1 (es) |
BR (1) | BR112015021072A2 (es) |
CA (1) | CA2902009A1 (es) |
HK (1) | HK1217323A1 (es) |
MX (1) | MX2015011470A (es) |
RU (1) | RU2015139514A (es) |
WO (1) | WO2014137576A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6021938B2 (ja) * | 2011-12-16 | 2016-11-09 | スリーエム イノベイティブ プロパティズ カンパニー | メルカプト含有ビスアンヒドロヘキシトール誘導体及びその使用 |
CN116554193A (zh) * | 2023-05-22 | 2023-08-08 | 吉林大学 | 异山梨醇衍生的二元酯、酸、醇单体及其合成方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2903983A1 (de) * | 1979-02-02 | 1980-09-04 | Sanol Arznei Schwarz Gmbh | Verfahren zur selektiven herstellung von isosorbid-2-nitrat |
DE3028340C2 (de) * | 1980-07-25 | 1987-02-05 | Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe | Amino-desoxy-1.4;3.6-dianhydro-hexit-nitrate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
DE3606634A1 (de) * | 1986-02-28 | 1987-09-03 | Mack Chem Pharm | Isohexid-nucleoside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
JP3696882B2 (ja) * | 1993-07-23 | 2005-09-21 | メレル ファーマス−ティカルズ インコーポレイテッド | プロ炎症性サイトカインの選択的抑制剤として有用な新規な9−n−二環式ヌクレオシド剤 |
ES2142773B1 (es) * | 1998-10-07 | 2001-01-01 | Lacer Sa | Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida. |
EP1299335B1 (en) * | 2000-07-13 | 2007-09-05 | MERCK PATENT GmbH | Chiral compounds ii |
ES2258365B1 (es) * | 2003-10-03 | 2007-12-01 | Lacer, S.A. | Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos. |
US7619056B2 (en) * | 2006-06-02 | 2009-11-17 | New Jersey Institute Of Technology | Thermoset epoxy polymers from renewable resources |
EP1941876A1 (en) * | 2006-12-28 | 2008-07-09 | Lacer, S.A. | Isosorbide mononitrate derivatives for the treatment of Inflammation and ocular hypertension |
FR2915483B1 (fr) * | 2007-04-27 | 2009-06-12 | Arkema France | Nouveaux composes fonctionnels a coeur d'isosorbide ou d'isomere d'isosorbide, procede de fabrication et applications de ces composes |
ES2393049T3 (es) * | 2008-02-07 | 2012-12-18 | Nicox S.A. | Compuestos donantes de óxido nítrico |
EP2149576A1 (en) * | 2008-07-22 | 2010-02-03 | Lacer, S.A. | Isosorbide Nitrates having vasodilating activity |
EP2149577B1 (en) * | 2008-07-22 | 2011-04-27 | Lacer, S.A. | New stereospecific method for the preparation of dioxa-bicyclooctane compounds |
CN103349285A (zh) * | 2008-11-14 | 2013-10-16 | 阿彻丹尼尔斯米德兰德公司 | 有机凝胶组合物及其生产方法 |
EP2199294A1 (en) * | 2008-12-19 | 2010-06-23 | Lacer, S.A. | New stereospecific method for the preparation of dioxa bicyclooctane nitrate compounds |
EP2448944A4 (en) * | 2009-07-02 | 2012-11-28 | Senomyx Inc | Isomannide derivatives and their use as flavorings |
EP2388262A1 (en) * | 2010-05-20 | 2011-11-23 | Stichting Dutch Polymer Institute | New biobased chiral compounds |
-
2014
- 2014-02-18 US US14/771,818 patent/US20160016969A1/en not_active Abandoned
- 2014-02-18 MX MX2015011470A patent/MX2015011470A/es unknown
- 2014-02-18 WO PCT/US2014/016758 patent/WO2014137576A1/en active Application Filing
- 2014-02-18 JP JP2015561370A patent/JP2016510740A/ja not_active Withdrawn
- 2014-02-18 RU RU2015139514A patent/RU2015139514A/ru not_active Application Discontinuation
- 2014-02-18 CA CA2902009A patent/CA2902009A1/en not_active Abandoned
- 2014-02-18 EP EP14760241.1A patent/EP2964653A4/en not_active Withdrawn
- 2014-02-18 BR BR112015021072A patent/BR112015021072A2/pt not_active IP Right Cessation
- 2014-02-18 CN CN201480010785.9A patent/CN105026402A/zh active Pending
- 2014-02-18 KR KR1020157027282A patent/KR20150123324A/ko not_active Application Discontinuation
- 2014-02-18 AU AU2014226533A patent/AU2014226533A1/en not_active Abandoned
-
2016
- 2016-04-29 HK HK16104965.5A patent/HK1217323A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20160016969A1 (en) | 2016-01-21 |
JP2016510740A (ja) | 2016-04-11 |
CA2902009A1 (en) | 2014-09-12 |
WO2014137576A1 (en) | 2014-09-12 |
BR112015021072A2 (pt) | 2017-07-18 |
HK1217323A1 (zh) | 2017-01-06 |
EP2964653A4 (en) | 2016-11-30 |
KR20150123324A (ko) | 2015-11-03 |
RU2015139514A (ru) | 2017-04-07 |
EP2964653A1 (en) | 2016-01-13 |
AU2014226533A1 (en) | 2015-08-13 |
CN105026402A (zh) | 2015-11-04 |
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