MX2015010875A - Microorganismo recombinante para utilizar en metodo con produccion aumentada de producto. - Google Patents

Microorganismo recombinante para utilizar en metodo con produccion aumentada de producto.

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Publication number
MX2015010875A
MX2015010875A MX2015010875A MX2015010875A MX2015010875A MX 2015010875 A MX2015010875 A MX 2015010875A MX 2015010875 A MX2015010875 A MX 2015010875A MX 2015010875 A MX2015010875 A MX 2015010875A MX 2015010875 A MX2015010875 A MX 2015010875A
Authority
MX
Mexico
Prior art keywords
organism
recombinant
product yield
micro
increased product
Prior art date
Application number
MX2015010875A
Other languages
English (en)
Inventor
Antonius Jeroen Adriaan Van Maris
Jacobus Thomas Pronk
Victor Gabriel Guadalupe Medina
Hendrik Wouter Wisselink
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Univ Delft Tech
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Publication date
Application filed by Univ Delft Tech filed Critical Univ Delft Tech
Publication of MX2015010875A publication Critical patent/MX2015010875A/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01019Phosphoribulokinase (2.7.1.19)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01039Ribulose-bisphosphate carboxylase (4.1.1.39)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La invención se refiere a una célula de levadura recombinante, en particular una célula de levadura transgénica, que expresa funcionalmente una o más secuencias recombinantes, en particular heterólogas, de ácidos nucleicos que codifican ribulosa-1,5-bifosfato carboxilasa oxigenasa (Rubisco) y fosforibuloquinasa (PRK). La invención se refiere además al uso de dióxido de carbono como un aceptor de electrones en un microorganismo quimiotrófico recombinante, en particular un microorganismo eucariótico.
MX2015010875A 2013-02-22 2014-02-21 Microorganismo recombinante para utilizar en metodo con produccion aumentada de producto. MX2015010875A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13156448 2013-02-22
PCT/NL2014/050106 WO2014129898A2 (en) 2013-02-22 2014-02-21 Recombinant micro-organism for use in method with increased product yield

Publications (1)

Publication Number Publication Date
MX2015010875A true MX2015010875A (es) 2016-06-02

Family

ID=47749689

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015010875A MX2015010875A (es) 2013-02-22 2014-02-21 Microorganismo recombinante para utilizar en metodo con produccion aumentada de producto.

Country Status (16)

Country Link
US (3) US10093937B2 (es)
EP (2) EP2958986B1 (es)
JP (1) JP2016511639A (es)
KR (1) KR20160002692A (es)
CN (2) CN105209598A (es)
AR (1) AR094859A1 (es)
AU (1) AU2014219510A1 (es)
BR (1) BR112015020111A8 (es)
CA (1) CA2902149C (es)
DK (1) DK2958986T3 (es)
EA (1) EA201591294A1 (es)
ES (1) ES2931313T3 (es)
HU (1) HUE060246T2 (es)
MX (1) MX2015010875A (es)
PL (1) PL2958986T3 (es)
WO (1) WO2014129898A2 (es)

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US11384368B2 (en) * 2017-09-29 2022-07-12 Dsm Ip Assets B.V. Glycerol free ethanol production
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Also Published As

Publication number Publication date
EP3318624A3 (en) 2018-06-06
HUE060246T2 (hu) 2023-02-28
AR094859A1 (es) 2015-09-02
DK2958986T3 (da) 2022-11-28
BR112015020111A2 (pt) 2017-07-18
CN109536398A (zh) 2019-03-29
WO2014129898A3 (en) 2014-12-18
KR20160002692A (ko) 2016-01-08
WO2014129898A2 (en) 2014-08-28
US20210147859A1 (en) 2021-05-20
EA201591294A1 (ru) 2016-01-29
US20180251773A1 (en) 2018-09-06
US10093937B2 (en) 2018-10-09
CA2902149A1 (en) 2014-08-28
CN109536398B (zh) 2023-08-04
EP3318624A2 (en) 2018-05-09
JP2016511639A (ja) 2016-04-21
EP2958986A2 (en) 2015-12-30
ES2931313T3 (es) 2022-12-28
CN105209598A (zh) 2015-12-30
EP2958986B1 (en) 2022-09-07
PL2958986T3 (pl) 2023-01-02
CA2902149C (en) 2022-07-26
BR112015020111A8 (pt) 2021-07-06
US20150353942A1 (en) 2015-12-10
AU2014219510A1 (en) 2015-08-27

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