MX2015002994A - Peptidos de inhibidores obtenidos del receptor desencadenante expresado en celulas mieloides de tipo 1 (trem-1) y transcrito similar a trem 1 (tlt-1) y usos de los mismos. - Google Patents

Peptidos de inhibidores obtenidos del receptor desencadenante expresado en celulas mieloides de tipo 1 (trem-1) y transcrito similar a trem 1 (tlt-1) y usos de los mismos.

Info

Publication number
MX2015002994A
MX2015002994A MX2015002994A MX2015002994A MX2015002994A MX 2015002994 A MX2015002994 A MX 2015002994A MX 2015002994 A MX2015002994 A MX 2015002994A MX 2015002994 A MX2015002994 A MX 2015002994A MX 2015002994 A MX2015002994 A MX 2015002994A
Authority
MX
Mexico
Prior art keywords
trem
tlt
transcript
peptides derived
myeloid cells
Prior art date
Application number
MX2015002994A
Other languages
English (en)
Inventor
Hafid Ait-Oufella
Marc Derive
Sébastien Gibot
Amir Boufenzer
Original Assignee
Inserm Inst Nat De La Santé Et De La Rech Médicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm Inst Nat De La Santé Et De La Rech Médicale filed Critical Inserm Inst Nat De La Santé Et De La Rech Médicale
Publication of MX2015002994A publication Critical patent/MX2015002994A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

La presente invención se refiere a un péptido que contiene por lo menos 6 aminoácidos consecutivos seleccionados de la secuencia de aminoácidos SEQ ID NO. 2 y una variante conservadora de la función. La invención también se refiere a un péptido que contiene por lo menos 6 aminoácidos consecutivos seleccionados de la secuencia de aminoácidos SEQ ID NO:1 o SEQ ID NO:2 y una variante conservadora de la función para uso en el tratamiento de una enfermedad cardiovascular.
MX2015002994A 2012-09-07 2013-09-09 Peptidos de inhibidores obtenidos del receptor desencadenante expresado en celulas mieloides de tipo 1 (trem-1) y transcrito similar a trem 1 (tlt-1) y usos de los mismos. MX2015002994A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12306079 2012-09-07
PCT/EP2013/068628 WO2014037565A2 (en) 2012-09-07 2013-09-09 Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof

Publications (1)

Publication Number Publication Date
MX2015002994A true MX2015002994A (es) 2016-01-14

Family

ID=46826397

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002994A MX2015002994A (es) 2012-09-07 2013-09-09 Peptidos de inhibidores obtenidos del receptor desencadenante expresado en celulas mieloides de tipo 1 (trem-1) y transcrito similar a trem 1 (tlt-1) y usos de los mismos.

Country Status (24)

Country Link
US (1) US9657081B2 (es)
EP (1) EP2892920B1 (es)
JP (1) JP6307080B2 (es)
KR (1) KR102181384B1 (es)
CN (1) CN104837865B (es)
AU (1) AU2013311606B2 (es)
CA (1) CA2884121C (es)
CY (1) CY1123014T1 (es)
DK (1) DK2892920T3 (es)
ES (1) ES2797625T3 (es)
HK (1) HK1212360A1 (es)
HR (1) HRP20200875T8 (es)
HU (1) HUE051557T2 (es)
IL (1) IL237615B (es)
LT (1) LT2892920T (es)
MX (1) MX2015002994A (es)
NZ (1) NZ705899A (es)
PL (1) PL2892920T3 (es)
PT (1) PT2892920T (es)
RS (1) RS60421B1 (es)
RU (1) RU2672341C2 (es)
SI (1) SI2892920T1 (es)
WO (1) WO2014037565A2 (es)
ZA (1) ZA201501779B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135961A (zh) * 2015-06-12 2018-06-08 台湾基督长老教会马偕医疗财团法人马偕纪念医院 调控免疫反应的方法及多肽
JP7023853B2 (ja) 2016-03-04 2022-02-22 アレクトル エルエルシー 抗ｔｒｅｍ１抗体及びその使用方法
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
WO2020036987A1 (en) 2018-08-13 2020-02-20 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
WO2021105137A1 (en) * 2019-11-25 2021-06-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Trem-1 inhibitors for the treatment of vaso-occlusions and tissue injuries in patients suffering from sickle cell disease
CA3180293A1 (en) * 2020-06-05 2021-12-09 Marc Derive Trem-1 inhibitor for use in the treatment of a subject suffering from a coronavirus infection
IL299149A (en) 2020-06-26 2023-02-01 Amgen Inc IL-10 mutants and their related proteins
WO2022189659A1 (en) 2021-03-12 2022-09-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Trem-1 inhibitors for the treatment of marfan syndrome
EP4359441A1 (en) 2021-06-25 2024-05-01 Amgen Inc. Treatment of cardiovascular disease with trem-1 antigen binding proteins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
CA2156725A1 (en) 1993-02-22 1994-09-01 Warren S. Pear Production of high titer helper-free retroviruses by transient transfection
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
NZ293261A (en) 1994-09-12 1998-11-25 Schering Ag Recombinant pallidipin protein, asp-pallidipin, which inhibits collagen induced platelet aggregation inhibitor
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
WO2002016416A2 (en) * 2000-08-22 2002-02-28 The Brigham And Women's Hospital, Inc. Diagnosis and treatment of cardiovascular conditions
US20040180409A1 (en) * 2003-03-16 2004-09-16 Mcvicar Daniel TLT-1, a novel platelet-associated receptor and uses therefor
GB0426146D0 (en) * 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
US7553936B2 (en) * 2006-12-04 2009-06-30 The United States of America as represented by Secretary Department of Health and Human Services Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions
JP2010534828A (ja) 2007-07-23 2010-11-11 ビオエクセル エスピーエー スクリーニング、療法及び診断
DE102009018620A1 (de) 2009-04-27 2010-10-28 Carefusion Germany 234 Gmbh Ansteuer- und Auswerteschaltung, Messgerät sowie Verfahren zum Messen der Konzentration eines Gases
JP5467313B2 (ja) * 2009-09-28 2014-04-09 国立大学法人 岡山大学 アテローム動脈硬化抑制剤
AU2011237851B2 (en) * 2010-04-08 2015-02-05 Inserm (Institut National De La Sante Et De La Recherche Medicale) Inhibiting peptides derived from TREM-Like Transcript 1 (TLT-1) and uses thereof

Also Published As

Publication number Publication date
EP2892920A2 (en) 2015-07-15
PL2892920T3 (pl) 2020-08-24
DK2892920T3 (da) 2020-06-08
US20150232531A1 (en) 2015-08-20
JP2015533791A (ja) 2015-11-26
US9657081B2 (en) 2017-05-23
CN104837865B (zh) 2019-09-24
HRP20200875T1 (hr) 2020-09-04
RU2015112625A (ru) 2016-10-27
KR20150110460A (ko) 2015-10-02
ZA201501779B (en) 2016-10-26
LT2892920T (lt) 2020-07-10
CA2884121C (en) 2021-10-12
ES2797625T3 (es) 2020-12-03
PT2892920T (pt) 2020-06-16
WO2014037565A2 (en) 2014-03-13
IL237615A0 (en) 2015-04-30
CA2884121A1 (en) 2014-03-13
AU2013311606B2 (en) 2017-10-05
WO2014037565A9 (en) 2015-06-11
RU2672341C2 (ru) 2018-11-14
EP2892920B1 (en) 2020-03-04
CY1123014T1 (el) 2021-10-29
HUE051557T2 (hu) 2021-03-01
KR102181384B1 (ko) 2020-11-20
CN104837865A (zh) 2015-08-12
AU2013311606A1 (en) 2015-04-09
NZ705899A (en) 2018-08-31
HRP20200875T8 (hr) 2021-04-30
WO2014037565A3 (en) 2014-05-15
IL237615B (en) 2018-12-31
HK1212360A1 (en) 2016-06-10
RS60421B1 (sr) 2020-07-31
JP6307080B2 (ja) 2018-04-04
SI2892920T1 (sl) 2020-08-31

Similar Documents

Publication Publication Date Title
NZ705899A (en) Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof
NZ602845A (en) Inhibiting peptides derived from trem-like transcript 1 (tlt-1) and uses thereof
MX2017016101A (es) Polinucleotidos y polipetidos de adenovirus.
MX348464B (es) Agente inductor de inmunidad.
UA110599C2 (uk) Пептид для імунотерапії пухлин, включаючи нейрональні пухлини та пухлини мозку
MX2008009493A (es) Peptido novedoso y uso del mismo.
MX2015003310A (es) Moleculas de union il-17a novedosas y usos medicos de las mismas.
WO2010144231A3 (en) Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles
NZ706884A (en) Fc gamma receptor iib variants
EA033145B1 (ru) Применение полученных из pedf пептидов в стимуляции регенерации мышцы, регенерации сухожилия или артериогенеза
NZ609474A (en) Fviii peptides for immune tolerance induction and immunodiagnostics
MX2014013394A (es) Sal de clorhidrato de un peptido y su uso en combinacion con otros peptidos para inmunoterapia.
NZ736652A (en) Short synthetic peptide for treating diseases and/or conditions related to angiogenesis
NZ729514A (en) Therapeutic multi-peptides t specific immune therapy for treatment of brain metastasis
WO2010103515A3 (en) Compositions and methods for prevention and treatment of neurodegenerative diseases
MX2017008505A (es) Composicion.
JP2015522582A5 (es)
GB201018125D0 (en) Peptide
NZ706202A (en) Peptide antagonists of the vasopressin-2 receptor
NZ593086A (en) Isolated peptide binding to human leukocyte antigen (HLA) and having cytotoxic T lymphocyte (CTL) inducibility
GB2517871A (en) Alternaria peptides
GB201019467D0 (en) Therapeutic agent
GB2526222A (en) Viral peptides
WO2012131680A3 (en) Compositions and methods for treating inflammation based on inhibiting cd151 activity
MX348455B (es) Un nuevo peptido analgesico proveniente del veneno de la araña brachypelma verdezy.