WO2012131680A3 - Compositions and methods for treating inflammation based on inhibiting cd151 activity - Google Patents
Compositions and methods for treating inflammation based on inhibiting cd151 activity Download PDFInfo
- Publication number
- WO2012131680A3 WO2012131680A3 PCT/IL2012/050111 IL2012050111W WO2012131680A3 WO 2012131680 A3 WO2012131680 A3 WO 2012131680A3 IL 2012050111 W IL2012050111 W IL 2012050111W WO 2012131680 A3 WO2012131680 A3 WO 2012131680A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- activity
- inhibiting
- compositions
- methods
- treating inflammation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
An isolated peptide comprising at least 20 consecutive amino acids of the amino acid sequence set forth in SEQ ID NO: 2, the peptide being shorter than 100 amino acids and having a CD151 inhibitory activity. Also provided are uses of this peptide.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161468109P | 2011-03-28 | 2011-03-28 | |
US61/468,109 | 2011-03-28 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2012131680A2 WO2012131680A2 (en) | 2012-10-04 |
WO2012131680A9 WO2012131680A9 (en) | 2012-12-13 |
WO2012131680A3 true WO2012131680A3 (en) | 2013-01-24 |
Family
ID=46051707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2012/050111 WO2012131680A2 (en) | 2011-03-28 | 2012-03-28 | Compositions and methods for treating inflammation |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2012131680A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014159813A1 (en) | 2013-03-13 | 2014-10-02 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010137020A1 (en) * | 2009-05-28 | 2010-12-02 | Yeda Research And Development Co. Ltd. | Methods of treating inflammation |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154600B (en) | 1971-02-10 | 1977-09-15 | Organon Nv | METHOD FOR THE DETERMINATION AND DETERMINATION OF SPECIFIC BINDING PROTEINS AND THEIR CORRESPONDING BINDABLE SUBSTANCES. |
NL154598B (en) | 1970-11-10 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING. |
NL154599B (en) | 1970-12-28 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING SPECIFIC BINDING PROTEINS AND THEIR CORRESPONDING BINDABLE SUBSTANCES, AND TEST PACKAGING. |
US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
NL171930C (en) | 1972-05-11 | 1983-06-01 | Akzo Nv | METHOD FOR DETERMINING AND DETERMINING BITES AND TEST PACKAGING. |
US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
US6777196B2 (en) | 1997-02-18 | 2004-08-17 | Genentech, Inc. | Neurturin receptor |
AP9901686A0 (en) | 1997-05-14 | 1999-12-31 | Rhone Poulenc Rorer Pharma | Peptide parathyroid hormone analogs. |
CA3149553C (en) | 2006-06-12 | 2023-11-21 | Aptevo Research And Development Llc | Single-chain multivalent binding proteins with effector function |
AU2007278054B2 (en) | 2006-07-24 | 2012-11-22 | Yeda Research And Development Co. Ltd. | Pharmaceutical compositions comprising CCL2 and use of same for the treatment of inflammation |
FR2907341B1 (en) | 2006-10-18 | 2012-08-17 | Pf Medicament | USE OF ANTI-CD151 ANTIBODY FOR THE TREATMENT OF CANCER |
FR2929946B1 (en) | 2008-04-11 | 2010-05-28 | Pf Medicament | NOVEL ANTI-CD151 ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER |
-
2012
- 2012-03-28 WO PCT/IL2012/050111 patent/WO2012131680A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010137020A1 (en) * | 2009-05-28 | 2010-12-02 | Yeda Research And Development Co. Ltd. | Methods of treating inflammation |
Non-Patent Citations (3)
Title |
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DATABASE Geneseq [Online] 24 January 2008 (2008-01-24), "Human tissue-derived glycoprotein peptide fragment SEQ ID NO:4850.", XP002683046, retrieved from EBI accession no. GSP:AJL89195 Database accession no. AJL89195 * |
FLAISHON LIAT ET AL: "Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesions", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 112, no. 13, 1 December 2008 (2008-12-01), pages 5016 - 5025, XP009138924, ISSN: 0006-4971, DOI: 10.1182/BLOOD-2007-12-129122 * |
YAUCH ROBERT L ET AL: "Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration", MOLECULAR BIOLOGY OF THE CELL, vol. 9, no. 10, October 1998 (1998-10-01), pages 2751 - 2765, XP002683047, ISSN: 1059-1524 * |
Also Published As
Publication number | Publication date |
---|---|
WO2012131680A9 (en) | 2012-12-13 |
WO2012131680A2 (en) | 2012-10-04 |
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