SI2892920T1 - Inhibicija peptidov, ki izvirajo iz sprožilnega receptorja, izraženih na TREM podobnem transkriptu 1 (TLT-1) mieloidnih celic (TREM-1), in njih uporaba - Google Patents

Inhibicija peptidov, ki izvirajo iz sprožilnega receptorja, izraženih na TREM podobnem transkriptu 1 (TLT-1) mieloidnih celic (TREM-1), in njih uporaba

Info

Publication number
SI2892920T1
SI2892920T1 SI201331729T SI201331729T SI2892920T1 SI 2892920 T1 SI2892920 T1 SI 2892920T1 SI 201331729 T SI201331729 T SI 201331729T SI 201331729 T SI201331729 T SI 201331729T SI 2892920 T1 SI2892920 T1 SI 2892920T1
Authority
SI
Slovenia
Prior art keywords
trem
tlt
transcript
peptides derived
myeloid cells
Prior art date
Application number
SI201331729T
Other languages
English (en)
Inventor
Sebastien Gibot
Amir Boufenzer
Hafid Ait-Oufella
Marc Derive
Original Assignee
Inserm (Institut National De La Sante Et De La Recherche Medicale)
Universite De Lorraine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm (Institut National De La Sante Et De La Recherche Medicale), Universite De Lorraine filed Critical Inserm (Institut National De La Sante Et De La Recherche Medicale)
Publication of SI2892920T1 publication Critical patent/SI2892920T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201331729T 2012-09-07 2013-09-09 Inhibicija peptidov, ki izvirajo iz sprožilnega receptorja, izraženih na TREM podobnem transkriptu 1 (TLT-1) mieloidnih celic (TREM-1), in njih uporaba SI2892920T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12306079 2012-09-07
EP13759234.1A EP2892920B1 (en) 2012-09-07 2013-09-09 Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof
PCT/EP2013/068628 WO2014037565A2 (en) 2012-09-07 2013-09-09 Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof

Publications (1)

Publication Number Publication Date
SI2892920T1 true SI2892920T1 (sl) 2020-08-31

Family

ID=46826397

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331729T SI2892920T1 (sl) 2012-09-07 2013-09-09 Inhibicija peptidov, ki izvirajo iz sprožilnega receptorja, izraženih na TREM podobnem transkriptu 1 (TLT-1) mieloidnih celic (TREM-1), in njih uporaba

Country Status (24)

Country Link
US (1) US9657081B2 (sl)
EP (1) EP2892920B1 (sl)
JP (1) JP6307080B2 (sl)
KR (1) KR102181384B1 (sl)
CN (1) CN104837865B (sl)
AU (1) AU2013311606B2 (sl)
CA (1) CA2884121C (sl)
CY (1) CY1123014T1 (sl)
DK (1) DK2892920T3 (sl)
ES (1) ES2797625T3 (sl)
HK (1) HK1212360A1 (sl)
HR (1) HRP20200875T8 (sl)
HU (1) HUE051557T2 (sl)
IL (1) IL237615B (sl)
LT (1) LT2892920T (sl)
MX (1) MX2015002994A (sl)
NZ (1) NZ705899A (sl)
PL (1) PL2892920T3 (sl)
PT (1) PT2892920T (sl)
RS (1) RS60421B1 (sl)
RU (1) RU2672341C2 (sl)
SI (1) SI2892920T1 (sl)
WO (1) WO2014037565A2 (sl)
ZA (1) ZA201501779B (sl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2757489C2 (ru) * 2015-06-12 2021-10-18 Маккэй Медикл Фаундэйшн Зе Пресбайтериэн Чёч Ин Тайвэнь Маккэй Мемориал Хоспитэл Способы и антитела для модуляции иммунного ответа
WO2017152102A2 (en) 2016-03-04 2017-09-08 Alector Llc Anti-trem1 antibodies and methods of use thereof
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
EP3836951A1 (en) 2018-08-13 2021-06-23 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
EP4065152A1 (en) * 2019-11-25 2022-10-05 Institut National de la Santé et de la Recherche Médicale (INSERM) Trem-1 inhibitors for the treatment of vaso-occlusions and tissue injuries in patients suffering from sickle cell disease
WO2021245291A1 (en) * 2020-06-05 2021-12-09 Inotrem Trem-1 inhibitor for use in the treatment of a subject suffering from a coronavirus infection
CN116209459A (zh) 2020-06-26 2023-06-02 美国安进公司 Il-10突变蛋白及其融合蛋白
WO2022189659A1 (en) 2021-03-12 2022-09-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Trem-1 inhibitors for the treatment of marfan syndrome
WO2022272018A1 (en) 2021-06-25 2022-12-29 Amgen Inc. Treatment of cardiovascular disease with trem-1 antigen binding proteins

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
WO1994019478A1 (en) 1993-02-22 1994-09-01 The Rockefeller University Production of high titer helper-free retroviruses by transient transfection
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
JPH10505502A (ja) 1994-09-12 1998-06-02 シェーリング アクチェンゲゼルシャフト 修飾されたコラーゲン誘導血小板凝集阻害剤パリジピンの製法
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
BR0107157A (pt) * 2000-08-22 2002-07-16 Brigham And Womens Hospital In Diagnose e tratamento de condições cardiovasculares
US20040180409A1 (en) * 2003-03-16 2004-09-16 Mcvicar Daniel TLT-1, a novel platelet-associated receptor and uses therefor
GB0426146D0 (en) * 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
US7553936B2 (en) 2006-12-04 2009-06-30 The United States of America as represented by Secretary Department of Health and Human Services Anti-TREM-like transcript-1 (TLT-1) antibodies and compositions
CN101821621A (zh) 2007-07-23 2010-09-01 拜奥克塞尔有限公司 筛选、治疗和诊断
DE102009018620A1 (de) 2009-04-27 2010-10-28 Carefusion Germany 234 Gmbh Ansteuer- und Auswerteschaltung, Messgerät sowie Verfahren zum Messen der Konzentration eines Gases
JP5467313B2 (ja) * 2009-09-28 2014-04-09 国立大学法人 岡山大学 アテローム動脈硬化抑制剤
US9255136B2 (en) 2010-04-08 2016-02-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Inhibiting peptides derived from TREM-like transcript 1 (TLT-1) and uses thereof

Also Published As

Publication number Publication date
LT2892920T (lt) 2020-07-10
EP2892920B1 (en) 2020-03-04
MX2015002994A (es) 2016-01-14
HUE051557T2 (hu) 2021-03-01
HK1212360A1 (en) 2016-06-10
IL237615A0 (en) 2015-04-30
NZ705899A (en) 2018-08-31
US9657081B2 (en) 2017-05-23
DK2892920T3 (da) 2020-06-08
RS60421B1 (sr) 2020-07-31
RU2672341C2 (ru) 2018-11-14
PL2892920T3 (pl) 2020-08-24
KR102181384B1 (ko) 2020-11-20
AU2013311606A1 (en) 2015-04-09
CA2884121A1 (en) 2014-03-13
WO2014037565A3 (en) 2014-05-15
CN104837865B (zh) 2019-09-24
CA2884121C (en) 2021-10-12
ES2797625T3 (es) 2020-12-03
CN104837865A (zh) 2015-08-12
JP2015533791A (ja) 2015-11-26
PT2892920T (pt) 2020-06-16
IL237615B (en) 2018-12-31
KR20150110460A (ko) 2015-10-02
RU2015112625A (ru) 2016-10-27
HRP20200875T1 (hr) 2020-09-04
CY1123014T1 (el) 2021-10-29
EP2892920A2 (en) 2015-07-15
ZA201501779B (en) 2016-10-26
WO2014037565A2 (en) 2014-03-13
WO2014037565A9 (en) 2015-06-11
HRP20200875T8 (hr) 2021-04-30
JP6307080B2 (ja) 2018-04-04
AU2013311606B2 (en) 2017-10-05
US20150232531A1 (en) 2015-08-20

Similar Documents

Publication Publication Date Title
HRP20200875T8 (hr) Inhibitorni peptidi porijeklom od aktivirajućeg receptora eksprimiranog na mijeloidnim stanicama-1 (trem-1)-sličnog transkripta 1 (tlt-1) i nihove upotrebe
PL2814844T3 (pl) Przeciwciała wiążące i blokujące receptor aktywujący wykazujący ekspresję na komórkach szpikowych -1 (trem-1)
SG10201801611SA (en) Solid phase peptide synthesis processes and associated systems
PT2555789T (pt) Péptidos inibidores derivados do transcrito 1 tipo-trem (tlt-1) e seus usos
IL236120A0 (en) Peptide analogs of exendin–4
HK1213024A1 (zh) 母體血漿的無創性產前分子染色體核型分析
EP2897135A4 (en) PROTECTIVE MATERIAL FOR CABLE BEAMS AND CABLE HARNESS PROTECTION ELEMENT
EP2744057A4 (en) WATERPROOF STRUCTURE FOR A CABLE TREE AND CABLE TREE
EP2578456A4 (en) DEVICE FOR PROTECTING AN OCCUPANT
PL3346273T3 (pl) Nowe, pochodzące od d3 d-enancjomeryczne peptydy i ich zastosowanie
EP2610619A4 (en) HEMOCININE-1 RECEPTOR AND HEMOCININE-1-PEPTIDE
IL235705A0 (en) Lentivirus vectors that include the mch type 1 promoter
GB201220899D0 (en) CD44v6-derived pegylated peptides
ZA201603274B (en) Recombinant peptide vaccines against ticks, and nucleotide sequences coding for the recombinant peptides
HK1213781A1 (zh) 衍生自 β的多肽及其用途
EP2697375A4 (en) EXPRESSION SYSTEM WITH AN IFN 2 SAR ELEMENT
GB201700529D0 (en) Laminin receptor peptide