MX2014007277A - Aparato de aerosolizacion para administracion de farmaco independiente del perfil de inhalacion. - Google Patents

Aparato de aerosolizacion para administracion de farmaco independiente del perfil de inhalacion.

Info

Publication number
MX2014007277A
MX2014007277A MX2014007277A MX2014007277A MX2014007277A MX 2014007277 A MX2014007277 A MX 2014007277A MX 2014007277 A MX2014007277 A MX 2014007277A MX 2014007277 A MX2014007277 A MX 2014007277A MX 2014007277 A MX2014007277 A MX 2014007277A
Authority
MX
Mexico
Prior art keywords
openings
receptacle
powder
pharmaceutical formulation
flow
Prior art date
Application number
MX2014007277A
Other languages
English (en)
Spanish (es)
Inventor
Leo Chan
Try Keith Ung
Jeffry Weers
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2014007277A publication Critical patent/MX2014007277A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
MX2014007277A 2011-12-16 2012-12-14 Aparato de aerosolizacion para administracion de farmaco independiente del perfil de inhalacion. MX2014007277A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161576735P 2011-12-16 2011-12-16
US201161576768P 2011-12-16 2011-12-16
PCT/US2012/069938 WO2013090841A2 (en) 2011-12-16 2012-12-14 Aerosolization apparatus for inhalation profile-independent drug delivery

Publications (1)

Publication Number Publication Date
MX2014007277A true MX2014007277A (es) 2014-07-28

Family

ID=47501481

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007277A MX2014007277A (es) 2011-12-16 2012-12-14 Aparato de aerosolizacion para administracion de farmaco independiente del perfil de inhalacion.

Country Status (13)

Country Link
US (1) US9744318B2 (enExample)
EP (1) EP2790761B1 (enExample)
JP (1) JP2015500712A (enExample)
KR (1) KR20140103939A (enExample)
CN (1) CN103998087B (enExample)
AU (1) AU2012351947B2 (enExample)
BR (1) BR112014014399A2 (enExample)
CA (1) CA2858247A1 (enExample)
ES (1) ES2924032T3 (enExample)
IL (1) IL232762A0 (enExample)
MX (1) MX2014007277A (enExample)
RU (1) RU2615076C2 (enExample)
WO (1) WO2013090841A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2857499A1 (en) 2010-10-01 2015-04-08 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
PT3682905T (pt) 2011-10-03 2022-04-07 Modernatx Inc Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações
ES2923757T3 (es) 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
PT2922554T (pt) 2012-11-26 2022-06-28 Modernatx Inc Arn modificado nas porções terminais
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
AR095222A1 (es) * 2013-04-03 2015-09-30 Sanofi Sa Elemento de medición para un dispositivo de inhalación y montaje para un dispositivo de inhalación que comprende un elemento de medición
EP3024523B1 (en) 2013-07-22 2018-08-29 Inhalation Sciences Sweden AB Apparatus and method for generating an aerosol
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
JP2017047130A (ja) * 2015-09-04 2017-03-09 原田車両設計株式会社 薬剤吸入装置
WO2017042696A1 (en) * 2015-09-09 2017-03-16 Novartis Ag Targeted delivery of spray-dried formulations to the lungs
CN205916436U (zh) * 2016-07-13 2017-02-01 深圳市合川医疗科技有限公司 一种泡罩穿刺元件
WO2018195086A1 (en) * 2017-04-17 2018-10-25 Respira Therapeutics, Inc. Powder dispersion devices and methods
EP3691616A1 (en) * 2017-10-02 2020-08-12 Novartis AG Method for preparing a pharmaceutical product
CN108635643B (zh) * 2018-06-04 2025-01-10 润生药业有限公司 一种干粉吸入装置
WO2019241651A1 (en) * 2018-06-15 2019-12-19 Valley Product Concepts, LLC Capsules for use in personal vaporizers
WO2020135920A1 (en) * 2018-12-28 2020-07-02 Université Libre de Bruxelles Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
CA3124939A1 (en) * 2019-04-04 2020-10-08 Novartis Ag Siremadlin succinate
CN110286064B (zh) * 2019-08-05 2021-07-27 贵州大学 一种矿物颗粒润湿性测量装置及其测量方法
CN115089825A (zh) * 2022-07-06 2022-09-23 苏州易合医药有限公司 肺部给药装置

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
CH684746A5 (de) 1993-02-25 1994-12-15 Alusuisse Lonza Services Ag Laminat.
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DE69535897D1 (de) 1994-03-07 2009-01-22 Nektar Therapeutics Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin
ATE387925T1 (de) 1994-09-21 2008-03-15 Nektar Therapeutics Vorrichtung und verfahren zum dispergieren von trockenen pulvermedikamenten
US5693609A (en) 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
AU706195B2 (en) 1995-04-14 1999-06-10 Inhale Therapeutic Systems Powdered pharmaceutical formulations having improved dispersibility
US6258341B1 (en) 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6270869B1 (en) 1998-12-02 2001-08-07 Alusuisse Technology & Management Ltd. Cold formable laminate films
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
DE60025019T2 (de) 1999-10-29 2006-08-24 Nektar Therapeutics, San Carlos Trockenpulverzusammensetzungen mit verbesserter dispersivität
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
SE0101825D0 (sv) * 2001-05-22 2001-05-22 Astrazeneca Ab An Inhalation device
GB0315509D0 (en) * 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
GB2405798A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
EP2668970B1 (en) * 2006-10-25 2016-07-06 Novartis AG Powder dispersion apparatus
EP2082764A1 (en) 2008-01-24 2009-07-29 Boehringer Ingelheim International GmbH Inhaler
US8834930B2 (en) * 2008-05-15 2014-09-16 Novartis Ag Pulmonary delivery of a fluoroquinolone
MY155524A (en) * 2008-06-13 2015-10-30 Mannkind Corp A dry powder inhaler and system for drug delivery
WO2010039200A2 (en) 2008-09-30 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with endless strips and cooperating piercers and related methods

Also Published As

Publication number Publication date
IL232762A0 (en) 2014-07-31
JP2015500712A (ja) 2015-01-08
RU2014128828A (ru) 2016-02-10
AU2012351947B2 (en) 2017-08-17
EP2790761B1 (en) 2022-05-11
RU2615076C2 (ru) 2017-04-03
US9744318B2 (en) 2017-08-29
WO2013090841A3 (en) 2013-08-08
ES2924032T3 (es) 2022-10-04
CA2858247A1 (en) 2013-06-20
US20140318539A1 (en) 2014-10-30
WO2013090841A2 (en) 2013-06-20
KR20140103939A (ko) 2014-08-27
EP2790761A2 (en) 2014-10-22
BR112014014399A2 (pt) 2017-06-13
AU2012351947A1 (en) 2014-06-26
CN103998087B (zh) 2017-04-05
CN103998087A (zh) 2014-08-20

Similar Documents

Publication Publication Date Title
WO2013090841A3 (en) Aerosolization apparatus for inhalation profile-independent drug delivery
WO2008081327A3 (en) Delivery devices
TWI653065B (zh) 尼古丁粉末吸入器、及將尼古丁吸入至一用戶之肺中的方法
SG155889A1 (en) Nasal delivery devices
EP2460555A3 (en) Nasal delivery device
WO2012041938A3 (en) Inhaler
PH12012502053A1 (en) A simple capsule-based inhaler
LV14539A (lv) Inhalators
NZ585490A (en) Metering device for inhaling a powdery substance activated by the suction airflow of the user
WO2007093310A3 (en) Dry powder inhaler device
JP2015500712A5 (enExample)
MX354459B (es) Mercado digial para la distribucion a tiempo de datos de evento.
MY180425A (en) A hinged capsule inhaler
UA102123C2 (uk) Інгаляційний пристрій (варіанти)
RU2016146350A (ru) Ингалятор ароматизированного никотинового порошка
GB2467388B (en) Inhaler
DK2570147T3 (da) Tørpulverinhalator og system til lægemiddelindgivelse
JP2015027559A5 (enExample)
MX2010001588A (es) Dispositivo de una sola pieza para almacenar, dosificar y mezclar un polvo con un diluyente.
IN2014CN05009A (enExample)
TW200607538A (en) Medicament inhaler device
EP2328556A4 (en) FORMULATIONS WITH LARGE SUPPORT PARTS FOR AEROSOLS FOR THE INHALATION OF DRY POWDER
JP2016530030A5 (enExample)
IN2014DN07474A (enExample)
WO2010011329A3 (en) The delivery of powdered drug via inhalation