MX2014005408A - Sistema de imagenología de modalidad doble para mapeo funcional y anatómico corregistrado. - Google Patents

Sistema de imagenología de modalidad doble para mapeo funcional y anatómico corregistrado.

Info

Publication number
MX2014005408A
MX2014005408A MX2014005408A MX2014005408A MX2014005408A MX 2014005408 A MX2014005408 A MX 2014005408A MX 2014005408 A MX2014005408 A MX 2014005408A MX 2014005408 A MX2014005408 A MX 2014005408A MX 2014005408 A MX2014005408 A MX 2014005408A
Authority
MX
Mexico
Prior art keywords
blood
coregistered
maps
imaging system
index
Prior art date
Application number
MX2014005408A
Other languages
English (en)
Inventor
Bryan Clingman
Jason Zalev
Alexander Oraevsky
Sergey Ermilov
Andre Conjusteau
Peter Brecht
Vyacheslav Nadvoretskiy
Richard Su
Donald G Herzog
Original Assignee
Seno Medical Instr Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/287,759 external-priority patent/US20130109950A1/en
Priority claimed from US13/341,950 external-priority patent/US8686335B2/en
Priority claimed from US13/507,217 external-priority patent/US9289191B2/en
Application filed by Seno Medical Instr Inc filed Critical Seno Medical Instr Inc
Priority claimed from US13/667,830 external-priority patent/US9757092B2/en
Priority claimed from US13/667,808 external-priority patent/US20130289381A1/en
Publication of MX2014005408A publication Critical patent/MX2014005408A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13Tomography
    • A61B8/14Echo-tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5261Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0204Acoustic sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312Breast evaluation or disorder diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0825Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the breast, e.g. mammography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Acoustics & Sound (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Un sistema de imagenología en tiempo real que proporciona imagenología ultrasónica e imagenología optoacústica corregistradas a través de la aplicación de la misma sonda portátil para genera y detectar señales optoacústicas y ultrasónicas. Estas señales se digitalizan, procesan y usan para reconstruir mapas anatómicos sobrepuestos con mapas de dos parámetros funcionales del índice de hemoglobina en sangre e índice de oxigenación de la sangre. El índice de hemoglobina en la sangre representa los cambios de concentración de hemoglobina en la sangre en las áreas de interés de diagnóstico con relación a la concentración en sangre de antecedente. El índice de oxigenación de la sangre representa los cambios de oxigenación de la sangre en las áreas de interés de diagnóstico con relación al nivel de oxigenación de la sangre de antecedente. Estos mapas corregistrados se pueden usar para diferenciar tumores malignos de manera no invasiva de tumores y quistes benignos.
MX2014005408A 2011-11-02 2012-11-02 Sistema de imagenología de modalidad doble para mapeo funcional y anatómico corregistrado. MX2014005408A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13/287,759 US20130109950A1 (en) 2011-11-02 2011-11-02 Handheld optoacoustic probe
US13/341,950 US8686335B2 (en) 2011-12-31 2011-12-31 System and method for adjusting the light output of an optoacoustic imaging system
US13/507,217 US9289191B2 (en) 2011-10-12 2012-06-13 System and method for acquiring optoacoustic data and producing parametric maps thereof
US13/667,830 US9757092B2 (en) 2011-11-02 2012-11-02 Method for dual modality optoacoustic imaging
PCT/US2012/063409 WO2013067419A1 (en) 2011-11-02 2012-11-02 Dual modality imaging system for coregistered functional and anatomical mapping
US13/667,808 US20130289381A1 (en) 2011-11-02 2012-11-02 Dual modality imaging system for coregistered functional and anatomical mapping

Publications (1)

Publication Number Publication Date
MX2014005408A true MX2014005408A (es) 2015-02-12

Family

ID=48192850

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005408A MX2014005408A (es) 2011-11-02 2012-11-02 Sistema de imagenología de modalidad doble para mapeo funcional y anatómico corregistrado.

Country Status (8)

Country Link
JP (2) JP6322578B2 (es)
KR (1) KR102117132B1 (es)
AU (2) AU2012332233B2 (es)
CA (1) CA2861089C (es)
IL (1) IL232414A0 (es)
MX (1) MX2014005408A (es)
SG (1) SG11201401986WA (es)
WO (1) WO2013067419A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9144383B2 (en) 2007-12-13 2015-09-29 The Board Of Trustees Of The University Of Arkansas Device and method for in vivo noninvasive magnetic manipulation of circulating objects in bioflows
US9451884B2 (en) 2007-12-13 2016-09-27 Board Of Trustees Of The University Of Arkansas Device and method for in vivo detection of clots within circulatory vessels
US20090156932A1 (en) 2007-12-13 2009-06-18 Board Of Trustees Of The University Of Arkansas Device and method for in vivo flow cytometry using the detection of photoacoustic waves
US8686335B2 (en) 2011-12-31 2014-04-01 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US20130116538A1 (en) 2011-11-02 2013-05-09 Seno Medical Instruments, Inc. Optoacoustic imaging systems and methods with enhanced safety
US10433732B2 (en) 2011-11-02 2019-10-08 Seno Medical Instruments, Inc. Optoacoustic imaging system having handheld probe utilizing optically reflective material
US9445786B2 (en) 2011-11-02 2016-09-20 Seno Medical Instruments, Inc. Interframe energy normalization in an optoacoustic imaging system
US11191435B2 (en) 2013-01-22 2021-12-07 Seno Medical Instruments, Inc. Probe with optoacoustic isolator
US20140005544A1 (en) 2011-11-02 2014-01-02 Seno Medical Instruments, Inc. System and method for providing selective channel sensitivity in an optoacoustic imaging system
US9814394B2 (en) 2011-11-02 2017-11-14 Seno Medical Instruments, Inc. Noise suppression in an optoacoustic system
US20130289381A1 (en) 2011-11-02 2013-10-31 Seno Medical Instruments, Inc. Dual modality imaging system for coregistered functional and anatomical mapping
WO2013134772A2 (en) 2012-03-09 2013-09-12 Seno Medical Instruments, Inc. Statistical mapping in an optoacoustic imaging system
JP6061571B2 (ja) * 2012-09-04 2017-01-18 キヤノン株式会社 被検体情報取得装置
CA2884954A1 (en) 2012-09-25 2014-04-03 Mark S. Smeltzer Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood
JP6472437B2 (ja) * 2013-09-04 2019-02-20 キヤノン株式会社 光音響装置、及び音響波受信装置
CN103512960B (zh) * 2013-09-27 2016-01-06 中国科学院声学研究所 一种超声阵列成像方法
KR20160067881A (ko) 2013-10-11 2016-06-14 세노 메디컬 인스투르먼츠 인코포레이티드 의료 이미징 내 컴포넌트 분리를 위한 시스템 및 방법
CN104739453A (zh) * 2013-12-31 2015-07-01 深圳市鹏瑞智能技术应用研究院 超声信号断层扫描成像系统及方法
JP6049209B2 (ja) * 2014-01-28 2016-12-21 富士フイルム株式会社 光音響計測用プローブおよびそれを備えた光音響計測装置
US10945610B2 (en) 2014-12-31 2021-03-16 Bioventures, Llc Devices and methods for fractionated photoacoustic flow cytometry
EP3749215A4 (en) * 2018-02-07 2021-12-01 Atherosys, Inc. DEVICE AND METHOD FOR CONTROLLING THE ULTRASONIC RECORDING OF THE PERIPHERAL ARTERIES IN THE TRANSVERSAL PLANE
WO2019195614A1 (en) * 2018-04-04 2019-10-10 Tomowave Laboratories, Inc. Quantitative imaging system and uses thereof
WO2020044337A1 (en) * 2018-08-29 2020-03-05 Tel Hashomer Medical Research Infrastructure And Services Ltd. System and method for determining oxygenated-blood content of biological tissue
US11832872B2 (en) 2019-04-01 2023-12-05 Anya L. Getman Resonating probe with optional sensor, emitter, and/or injection capability
JP7301676B2 (ja) * 2019-08-28 2023-07-03 キヤノンメディカルシステムズ株式会社 超音波診断装置、信号処理方法、及び信号処理プログラム
WO2021149127A1 (ja) * 2020-01-21 2021-07-29 オリンパス株式会社 赤血球分化モニタリング装置および赤血球分化モニタリング方法
CN111671436A (zh) * 2020-05-21 2020-09-18 东南大学 一种温度补偿的光声无创血红蛋白检测装置及检测方法
CN111839730B (zh) * 2020-07-07 2022-02-11 厦门大学附属翔安医院 一种用于引导肿瘤切除的光声成像手术导航平台
CN116138805B (zh) * 2022-12-30 2023-09-08 深圳开立生物医疗科技股份有限公司 光声超声多模态成像设备及方法、电子设备及存储介质
CN115868956A (zh) * 2023-03-01 2023-03-31 暨南大学附属第一医院(广州华侨医院) 一种用于光磁声成像的激励源抗干扰方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3974946B2 (ja) * 1994-04-08 2007-09-12 オリンパス株式会社 画像分類装置
JPH0961359A (ja) * 1995-08-29 1997-03-07 Hamamatsu Photonics Kk 濃度測定装置
US5830146A (en) * 1997-03-17 1998-11-03 Polartechnics Limited Sheathed probes for tissue type recognition
JPH1176232A (ja) * 1997-09-11 1999-03-23 Hitachi Medical Corp 超音波診断装置
US6827686B2 (en) * 2002-08-21 2004-12-07 Koninklijke Philips Electronics N.V. System and method for improved harmonic imaging
JP4406226B2 (ja) * 2003-07-02 2010-01-27 株式会社東芝 生体情報映像装置
JP4643153B2 (ja) * 2004-02-06 2011-03-02 株式会社東芝 非侵襲生体情報映像装置
IL166408A0 (en) * 2005-01-20 2006-01-15 Ultraview Ltd Combined 2d pulse-echo ultrasound and optoacousticsignal for glaucoma treatment
US9173573B2 (en) * 2005-02-23 2015-11-03 Koninklijke Philips N.V. Imaging an object of interest
JP4745743B2 (ja) * 2005-07-14 2011-08-10 Hoya株式会社 蛍光観察内視鏡システム
US20070093708A1 (en) * 2005-10-20 2007-04-26 Benaron David A Ultra-high-specificity device and methods for the screening of in-vivo tumors
US20070093702A1 (en) * 2005-10-26 2007-04-26 Skyline Biomedical, Inc. Apparatus and method for non-invasive and minimally-invasive sensing of parameters relating to blood
JP2007267837A (ja) * 2006-03-30 2007-10-18 Toshiba Corp 生体光計測装置
US8298144B2 (en) * 2006-06-23 2012-10-30 Koninklijke Philips Electronics N.V. Timing controller for combined photoacoustic and ultrasound imager
WO2008011112A2 (en) * 2006-07-19 2008-01-24 University Of Connecticut Method and apparatus for medical imaging using combined near-infrared optical tomography, fluorescent tomography and ultrasound
JP4820239B2 (ja) * 2006-08-28 2011-11-24 公立大学法人大阪府立大学 光トモグラフィ装置用プローブ
US20100056916A1 (en) * 2006-11-21 2010-03-04 Koninklijke Philips Electronics N.V. System, device, method, computer-readable medium, and use for in vivo imaging of tissue in an anatomical structure
US8302480B2 (en) * 2007-02-05 2012-11-06 Brown University Enhanced ultra-high resolution acoustic microscope
JP5002397B2 (ja) * 2007-09-28 2012-08-15 株式会社東芝 超音波診断装置及びプログラム
JP5643101B2 (ja) * 2007-10-25 2014-12-17 ワシントン・ユニバーシティWashington University 散乱媒体の画像化方法、画像化装置及び画像化システム
JP2010179085A (ja) * 2008-07-11 2010-08-19 Canon Inc 生体情報取得装置
WO2010009412A2 (en) * 2008-07-18 2010-01-21 University Of Rochester Medical Center Low-cost device for c-scan photoacoustic imaging
EP2344019B1 (en) * 2008-07-25 2013-11-27 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Quantitative multi-spectral opto-acoustic tomography (msot) of tissue biomarkers
JP4900979B2 (ja) * 2008-08-27 2012-03-21 キヤノン株式会社 光音響装置および光音響波を受信するための探触子
US20100094134A1 (en) * 2008-10-14 2010-04-15 The University Of Connecticut Method and apparatus for medical imaging using near-infrared optical tomography combined with photoacoustic and ultrasound guidance
US9528966B2 (en) * 2008-10-23 2016-12-27 Washington University Reflection-mode photoacoustic tomography using a flexibly-supported cantilever beam
JP2010125260A (ja) * 2008-12-01 2010-06-10 Canon Inc 生体検査装置
JP5241465B2 (ja) * 2008-12-11 2013-07-17 キヤノン株式会社 光音響イメージング装置および光音響イメージング方法
JP5275830B2 (ja) * 2009-01-26 2013-08-28 富士フイルム株式会社 光超音波断層画像化装置および光超音波断層画像化方法
JP5483905B2 (ja) * 2009-03-03 2014-05-07 キヤノン株式会社 超音波装置
JP4621781B2 (ja) * 2009-03-06 2011-01-26 株式会社東芝 レーザ超音波検査装置
EP2425402A2 (en) * 2009-05-01 2012-03-07 Visualsonics, Inc. System for photoacoustic imaging and related methods
JP2011072702A (ja) * 2009-10-01 2011-04-14 Konica Minolta Medical & Graphic Inc 超音波探触子用音響レンズおよび超音波探触子
JP5692988B2 (ja) * 2009-10-19 2015-04-01 キヤノン株式会社 音響波測定装置
EP2957232A1 (en) * 2009-10-29 2015-12-23 Canon Kabushiki Kaisha Photoacoustic apparatus
WO2011091423A2 (en) * 2010-01-25 2011-07-28 The Arizona Board Of Regents On Behalf Of The University Of Arizona Ultrasonic/photoacoustic imaging devices and methods
JP5818444B2 (ja) * 2010-02-04 2015-11-18 キヤノン株式会社 機能情報取得装置、機能情報取得方法、及びプログラム
JP5448918B2 (ja) * 2010-02-24 2014-03-19 キヤノン株式会社 生体情報処理装置
JP5479173B2 (ja) * 2010-03-17 2014-04-23 キヤノン株式会社 情報処理装置および情報処理方法

Also Published As

Publication number Publication date
CA2861089C (en) 2021-01-12
KR20140103932A (ko) 2014-08-27
IL232414A0 (en) 2014-06-30
JP2018143778A (ja) 2018-09-20
JP6732830B2 (ja) 2020-07-29
AU2012332233B2 (en) 2017-08-31
KR102117132B1 (ko) 2020-05-29
AU2017268522A1 (en) 2017-12-14
AU2012332233A1 (en) 2014-05-22
JP2015501194A (ja) 2015-01-15
CA2861089A1 (en) 2013-05-10
SG11201401986WA (en) 2014-08-28
WO2013067419A1 (en) 2013-05-10
JP6322578B2 (ja) 2018-05-09

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