MX2014002767A - Adsorbente nanoparticulado de fosfato en base a maghemita o maghemita/magnetita, su produccion y usos. - Google Patents

Adsorbente nanoparticulado de fosfato en base a maghemita o maghemita/magnetita, su produccion y usos.

Info

Publication number
MX2014002767A
MX2014002767A MX2014002767A MX2014002767A MX2014002767A MX 2014002767 A MX2014002767 A MX 2014002767A MX 2014002767 A MX2014002767 A MX 2014002767A MX 2014002767 A MX2014002767 A MX 2014002767A MX 2014002767 A MX2014002767 A MX 2014002767A
Authority
MX
Mexico
Prior art keywords
maghemite
phosphate adsorbent
magnetite
basis
production
Prior art date
Application number
MX2014002767A
Other languages
English (en)
Other versions
MX351270B (es
Inventor
Susanne Wagner
Matthias Taupitz
Eyk Schellenberger
Jörg Schnorr
Monika Ebert
Gesche Genter
Harald Kratz
Original Assignee
Charité Universitätsmedizin Berlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charité Universitätsmedizin Berlin filed Critical Charité Universitätsmedizin Berlin
Publication of MX2014002767A publication Critical patent/MX2014002767A/es
Publication of MX351270B publication Critical patent/MX351270B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/02—Oxides; Hydroxides
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/02—Oxides; Hydroxides
    • C01G49/06—Ferric oxide [Fe2O3]
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/30—Three-dimensional structures
    • C01P2002/32—Three-dimensional structures spinel-type (AB2O4)
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/60—Compounds characterised by their crystallite size
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer

Abstract

Un adsorbente de fosfato en base a maghemita o maghemita/magnetita que comprende (i) un núcleo de óxido de hierro que comprende una estructura cristalina de óxido de hierro espinela invertida, (ii) un recubrimiento seleccionado de hidratos de carbono monoméricos, en particular monosacáridos o disacáridos, alditoles, o mezclas de los mismos, y/o (iii) un excipiente farmacéutico seleccionado de hidratos de carbono poliméricos, en donde el adsorbente de fosfato tiene la forma de nanopartículas con un tamaño de partícula del núcleo de óxido de hierro (i) menor de 20 nm. La presente invención además se relaciona con un método para la producción de un adsorbente de fosfato en base a maghemita o maghemita/magnetita, para composiciones farmacéuticas que comprenden el adsorbente de fosfato, y para usos médicos de las mismas, especialmente para la prevención y/o tratamiento de hiperfosfatemia.
MX2014002767A 2011-09-08 2012-09-03 Adsorbente nanoparticulado de fosfato en base a maghemita o maghemita/magnetita, su produccion y usos. MX351270B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102011112898A DE102011112898A1 (de) 2011-09-08 2011-09-08 Nanopartikuläres Phosphatadsorbens basierend auf Maghämit oder Maghämit/Magnetit, dessen Herstellung und Verwendungen
US201161537127P 2011-09-21 2011-09-21
PCT/EP2012/003676 WO2013034267A1 (en) 2011-09-08 2012-09-03 Nanoparticulate phosphate adsorbent on the basis of maghemite or maghemite/magnetite, production and uses thereof

Publications (2)

Publication Number Publication Date
MX2014002767A true MX2014002767A (es) 2014-06-05
MX351270B MX351270B (es) 2017-10-06

Family

ID=47740070

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002767A MX351270B (es) 2011-09-08 2012-09-03 Adsorbente nanoparticulado de fosfato en base a maghemita o maghemita/magnetita, su produccion y usos.

Country Status (15)

Country Link
US (1) US10548874B2 (es)
EP (1) EP2753340B1 (es)
JP (1) JP6227532B2 (es)
KR (1) KR101951857B1 (es)
CN (1) CN103906523B (es)
AU (1) AU2012306775B2 (es)
BR (1) BR112014005250B1 (es)
CA (1) CA2848006C (es)
DE (1) DE102011112898A1 (es)
DK (1) DK2753340T3 (es)
ES (1) ES2658158T3 (es)
MX (1) MX351270B (es)
PL (1) PL2753340T3 (es)
WO (1) WO2013034267A1 (es)
ZA (1) ZA201401493B (es)

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JP6417339B2 (ja) * 2013-03-08 2018-11-07 ヴィダシム・インコーポレーテッド 金属イオン−機能性繊維成分錯体組成物、その調製および使用
US10172882B2 (en) 2014-06-22 2019-01-08 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
CN106536420A (zh) * 2014-07-22 2017-03-22 康宁股份有限公司 用于水的重金属治理的过滤器和方法
DE102014019388A1 (de) 2014-12-29 2016-06-30 Susanne Wagner Arzneimittel auf der Basis von Maghämit zur gleichzeitigen Reduzierung der gastrointestinalen Natriumresorption und Phosphatresorption
JP6621834B2 (ja) * 2015-10-09 2019-12-18 日本曹達株式会社 オキシ水酸化鉄ナノ分散液
WO2017061117A1 (ja) * 2015-10-09 2017-04-13 高橋金属株式会社 吸着材分散液及び吸着方法
CN107397758A (zh) * 2016-05-19 2017-11-28 欣凯医药化工中间体（上海）有限公司 一种磷结合剂及其制备方法
CN107397810B (zh) * 2016-05-19 2021-08-24 欣凯医药化工中间体（上海）有限公司 基于铁的氢氧化物－桃胶的磷结合剂、其制备方法及其应用
CN106390909B (zh) * 2016-11-03 2018-10-26 孙顺秋 一种双壳层空心结构的四氧化三铁磁性重金属离子吸附剂及其制备方法
CN106865682A (zh) * 2017-04-14 2017-06-20 北京师范大学 水铁矿‑mf/uf膜组合工艺去除有机物与磷酸盐的方法
MX2020004107A (es) * 2017-10-25 2020-07-24 Chiesi Farm Spa Tabletas de deferiprona de liberacion retrasada y metodos de uso de las mismas.
CN109953973A (zh) * 2017-12-22 2019-07-02 蔡晓辉 一种新型pH敏感磁靶向纳米载药体系及其制备方法和应用
WO2021116733A1 (en) * 2019-12-11 2021-06-17 Politechnika Krakowska im. Tadeusza Kościuszki Method of manufacturing modified titanium (iv) oxide nanoparticles and modified titanium (iv) oxide nanoparticles
CN114950352B (zh) * 2021-02-26 2023-11-10 广州大学 一种碳酸镧改性Fe3O4@C除磷吸附剂及其制备方法和应用
CN115155537B (zh) * 2022-07-28 2023-05-09 安徽农业大学 FeOOH功能化腈纶纤维及其制备方法和应用

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EP0093757A1 (en) * 1981-11-12 1983-11-16 Ulf SCHRÖDER Intravascularly administrable, magnetically responsive nanosphere or nanoparticle, a process for the production thereof, and the use thereof
DE3508000A1 (de) * 1985-03-04 1986-09-04 Schering AG, Berlin und Bergkamen, 1000 Berlin Ferromagnetische partikel fuer die nmr-diagnostik
US4970079A (en) 1989-06-05 1990-11-13 Purdue Research Foundation Method and composition of oxy-iron compounds for treatment of hyperphosphatemia
DE10199065I2 (de) * 1991-01-19 2004-09-23 Meito Sangyo Kk Ultrafeine magnetische metalloxidteilchen enthalten de zusammensetzung
JPH0525051A (ja) * 1991-07-19 1993-02-02 Meiji Seika Kaisha Ltd 貧血予防・治療剤
DE4325386C2 (de) * 1993-07-23 1997-07-10 Polychemie Velten Gmbh pH-neutrale magnetische Flüssigkeit auf Basis einer wäßrigen Trägerflüssigkeit, Verfahren zu ihrer Herstellung sowie Verwendung
JP3854631B2 (ja) * 1993-08-12 2006-12-06 アドバンスド・マグネティクス・インク 多糖類で被覆された超常磁性酸化物コロイドの合成
JPH10218779A (ja) * 1997-02-10 1998-08-18 Nippon Electric Glass Co Ltd 温熱治療材料
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
US20030185757A1 (en) * 2002-03-27 2003-10-02 Mayk Kresse Iron-containing nanoparticles with double coating and their use in diagnosis and therapy
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
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Also Published As

Publication number Publication date
BR112014005250B1 (pt) 2020-03-10
PL2753340T3 (pl) 2018-04-30
ZA201401493B (en) 2014-11-26
EP2753340B1 (en) 2017-11-08
AU2012306775A1 (en) 2014-03-27
BR112014005250A2 (pt) 2017-06-06
ES2658158T3 (es) 2018-03-08
EP2753340A1 (en) 2014-07-16
AU2012306775B2 (en) 2017-05-04
CA2848006C (en) 2019-10-08
CN103906523B (zh) 2017-10-27
MX351270B (es) 2017-10-06
JP2014528929A (ja) 2014-10-30
KR20140068941A (ko) 2014-06-09
CN103906523A (zh) 2014-07-02
WO2013034267A1 (en) 2013-03-14
KR101951857B1 (ko) 2019-02-25
AU2012306775A2 (en) 2014-04-03
US10548874B2 (en) 2020-02-04
US20140248363A1 (en) 2014-09-04
CA2848006A1 (en) 2013-03-14
DK2753340T3 (en) 2018-02-05
DE102011112898A1 (de) 2013-03-14
JP6227532B2 (ja) 2017-11-08

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