EA201400193A1 - Наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, биосовместимые водные коллоидные системы, включающие в себя наночастицы, феррилипосомы, и их использование - Google Patents

Наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, биосовместимые водные коллоидные системы, включающие в себя наночастицы, феррилипосомы, и их использование

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Publication number
EA201400193A1
EA201400193A1 EA201400193A EA201400193A EA201400193A1 EA 201400193 A1 EA201400193 A1 EA 201400193A1 EA 201400193 A EA201400193 A EA 201400193A EA 201400193 A EA201400193 A EA 201400193A EA 201400193 A1 EA201400193 A1 EA 201400193A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nanoparticles
oxide
ferrimagnets
spinel structure
ferriliposomy
Prior art date
Application number
EA201400193A
Other languages
English (en)
Other versions
EA029170B1 (ru
Inventor
Ольга ВАСИЛЬЕВА
Воля Исаевич Итин
Сергей Григорьевич ПСАХЬЕ
Георгий Андреевич МИХАЙЛОВ
Мойца Уршка Микац
Борис ТУРК
Анна Алексеевна Магаева
Евгений Петрович Найден
Ольга Георгиевна Терехова
Original Assignee
Федеральное государственное бюджетное учреждение науки Институт физики прочности и материаловедения Сибирского отделения Российской академии наук (ИФПМ СО РАН)
Институт Йожефа Стефана
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/RU2011/000574 external-priority patent/WO2013019137A1/en
Priority claimed from RU2011132913/15A external-priority patent/RU2471502C1/ru
Application filed by Федеральное государственное бюджетное учреждение науки Институт физики прочности и материаловедения Сибирского отделения Российской академии наук (ИФПМ СО РАН), Институт Йожефа Стефана filed Critical Федеральное государственное бюджетное учреждение науки Институт физики прочности и материаловедения Сибирского отделения Российской академии наук (ИФПМ СО РАН)
Publication of EA201400193A1 publication Critical patent/EA201400193A1/ru
Publication of EA029170B1 publication Critical patent/EA029170B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/02—Oxides; Hydroxides
    • C01G49/08—Ferroso-ferric oxide [Fe3O4]
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G51/00—Compounds of cobalt
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/30—Three-dimensional structures
    • C01P2002/32—Three-dimensional structures spinel-type (AB2O4)
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/50—Solid solutions
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/03—Particle morphology depicted by an image obtained by SEM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/51—Particles with a specific particle size distribution
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/51—Particles with a specific particle size distribution
    • C01P2004/52—Particles with a specific particle size distribution highly monodisperse size distribution
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/12—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
    • H01F1/34—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites
    • H01F1/342—Oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Power Engineering (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Iron (AREA)
  • Medicinal Preparation (AREA)

Abstract

Предметом настоящего изобретения являются способы получения наночастиц оксидных ферримагнетиков со структурой шпинели и наночастиц оксидов железа на основе механохимического синтеза, наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа сверхмалого размера с большой удельной поверхностью, получаемые данными способами, биосовместимые водные коллоидные системы, включающие в себя наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, феррилипосомы, содержащие наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, и способы их применения в медицине.
EA201400193A 2011-08-04 2012-08-03 Наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, биосовместимые водные коллоидные системы, включающие в себя наночастицы, феррилипосомы, и их использование EA029170B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/RU2011/000574 WO2013019137A1 (en) 2011-08-04 2011-08-04 Oxide ferrimagnetics with spinel structure nanoparticles and iron oxide nanoparticles, biocompatible aqueous colloidal systems comprising nanoparticles, ferriliposomes, and uses thereof
RU2011132913/15A RU2471502C1 (ru) 2011-08-04 2011-08-04 Контрастное средство для t1 и/или t2 магнитно-резонансного сканирования и способ его получения
PCT/RU2012/000632 WO2013019151A2 (en) 2011-08-04 2012-08-03 Oxide ferrimagnetics with spinel structure nanoparticles and iron oxide nanoparticles, biocompatible aqueous colloidal systems comprising nanoparticles, ferriliposomes, and uses thereof

Publications (2)

Publication Number Publication Date
EA201400193A1 true EA201400193A1 (ru) 2014-11-28
EA029170B1 EA029170B1 (ru) 2018-02-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400193A EA029170B1 (ru) 2011-08-04 2012-08-03 Наночастицы оксидных ферримагнетиков со структурой шпинели и наночастицы оксидов железа, биосовместимые водные коллоидные системы, включающие в себя наночастицы, феррилипосомы, и их использование

Country Status (5)

Country Link
US (1) US20140186268A1 (ru)
EP (1) EP2739291A4 (ru)
BR (1) BR112014002755A2 (ru)
EA (1) EA029170B1 (ru)
WO (1) WO2013019151A2 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8954131B2 (en) * 2007-06-19 2015-02-10 The Trustees Of Dartmouth College Magnetic particle imaging (MPI) system and method for use of iron-based nanoparticles in imaging and diagnosis
CN104538145B (zh) * 2014-12-08 2017-02-22 浙江师范大学 一种多尺度、均一、单分散磁性微球及其制备方法
CN105931786A (zh) * 2016-07-14 2016-09-07 安徽万磁电子有限公司 一种镝钇离子注入的镀镍钕铁硼磁体及其制备方法
US11348702B2 (en) * 2016-08-11 2022-05-31 Battelle Memorial Institute System, emanation generator, and process for production of high-purity therapeutic radioisotopes
CN106421813B (zh) * 2016-10-21 2019-07-26 新乡医学院 具有双重靶向功能的载药纳米粒子及其制备方法和应用
CN109626439B (zh) * 2018-12-11 2024-05-07 中国科学院宁波材料技术与工程研究所 一种金属掺杂铁氧体纳米材料、包含其的磁性纳米粒子的制备方法及其应用
US11207348B2 (en) 2019-04-25 2021-12-28 Imam Abdulrahman Bin Faisal University Spinel ferrite impregnated mesoporous silica containing a platinum complex
CN110124036B (zh) * 2019-06-10 2020-11-20 西安电子科技大学 多功能磁性纳米探针及其制备方法
CN112274657B (zh) * 2020-09-17 2022-04-01 浙江大学 一种t1-t2双模态超高场磁共振造影剂及其制备方法和应用
CN113398285B (zh) * 2021-06-09 2022-09-02 哈尔滨工程大学 一种具有抗肿瘤效应的双金属纳米酶复合材料的制备方法
CN113484469B (zh) * 2021-06-30 2022-11-18 中国科学院青海盐湖研究所 水合盐体系相变储能材料纳米尺度相分离的原位表征方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US20020012698A1 (en) * 1999-09-01 2002-01-31 Edmund Bauerlein Magnetosomes, method for making and using
ITFI20030038A1 (it) * 2003-02-13 2004-08-14 Colorobbia Italiana Spa Composizioni comprendenti liposomi contenenti nanoparticelle
WO2006051732A1 (ja) * 2004-11-10 2006-05-18 Konica Minolta Medical & Graphic, Inc. 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム

Also Published As

Publication number Publication date
EA029170B1 (ru) 2018-02-28
EP2739291A4 (en) 2015-03-11
US20140186268A1 (en) 2014-07-03
WO2013019151A2 (en) 2013-02-07
BR112014002755A2 (pt) 2017-02-21
EP2739291A2 (en) 2014-06-11
WO2013019151A3 (en) 2013-04-11

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU