EA201600412A1 - Способ производства неорганического материала в виде частиц - Google Patents

Способ производства неорганического материала в виде частиц

Info

Publication number
EA201600412A1
EA201600412A1 EA201600412A EA201600412A EA201600412A1 EA 201600412 A1 EA201600412 A1 EA 201600412A1 EA 201600412 A EA201600412 A EA 201600412A EA 201600412 A EA201600412 A EA 201600412A EA 201600412 A1 EA201600412 A1 EA 201600412A1
Authority
EA
Eurasian Patent Office
Prior art keywords
particles
inorganic material
manufacturing inorganic
manufacturing
administering
Prior art date
Application number
EA201600412A
Other languages
English (en)
Inventor
Шон Куцера
Дитер Лубда
Ларс Фридрих
Ванесса Витт
Original Assignee
Мерк Патент Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Патент Гмбх filed Critical Мерк Патент Гмбх
Publication of EA201600412A1 publication Critical patent/EA201600412A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J6/00—Heat treatments such as Calcining; Fusing ; Pyrolysis
    • B01J6/001—Calcining
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/14—Colloidal silica, e.g. dispersions, gels, sols
    • C01B33/141—Preparation of hydrosols or aqueous dispersions
    • C01B33/142—Preparation of hydrosols or aqueous dispersions by acidic treatment of silicates
    • C01B33/143—Preparation of hydrosols or aqueous dispersions by acidic treatment of silicates of aqueous solutions of silicates
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/18—Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/18—Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof
    • C01B33/187—Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof by acidic treatment of silicates
    • C01B33/193—Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof by acidic treatment of silicates of aqueous solutions of silicates
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/16—Pore diameter

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Silicon Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)

Abstract

Настоящее изобретение относится к способу производства неорганического материала в виде частиц, к материалу, который можно получить посредством такого способа, к системе доставки с модифицированным высвобождением, содержащей материал, и к применению материала для введения биологически активного вещества.
EA201600412A 2013-11-26 2014-10-31 Способ производства неорганического материала в виде частиц EA201600412A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13005505 2013-11-26
EP13005688 2013-12-06
PCT/EP2014/002929 WO2015078552A1 (en) 2013-11-26 2014-10-31 Process for producing inorganic particulate material

Publications (1)

Publication Number Publication Date
EA201600412A1 true EA201600412A1 (ru) 2016-10-31

Family

ID=51862253

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201600412A EA201600412A1 (ru) 2013-11-26 2014-10-31 Способ производства неорганического материала в виде частиц

Country Status (12)

Country Link
US (1) US20160374943A1 (ru)
EP (1) EP3074344B1 (ru)
JP (1) JP2016539903A (ru)
KR (1) KR20160089504A (ru)
CN (1) CN105764852A (ru)
AU (1) AU2014356854B2 (ru)
CA (1) CA2931362A1 (ru)
EA (1) EA201600412A1 (ru)
HK (1) HK1222165A1 (ru)
IL (1) IL245692A0 (ru)
MX (1) MX2016006738A (ru)
WO (1) WO2015078552A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10954393B2 (en) * 2016-05-17 2021-03-23 University Of South Carolina Tunable nanomaterials by templating from kinetically trapped polymer micelles
US11471386B2 (en) 2017-12-29 2022-10-18 Conopco, Inc. Non-spherical microcapsule
CN111542303B (zh) 2017-12-29 2023-07-25 联合利华知识产权控股有限公司 非球形微囊
WO2020127281A1 (en) 2018-12-20 2020-06-25 Merck Patent Gmbh A release system comprising a bioactive agent and a particulate material
WO2021069074A1 (en) * 2019-10-10 2021-04-15 Sil'innov Srcl Silica with ultra-fast dissolution properties

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58104017A (ja) * 1981-12-14 1983-06-21 Fuji Photo Film Co Ltd 全多孔性球状状シリカゲル粒子及びその製造方法
JPS6071515A (ja) * 1983-09-29 1985-04-23 Mitsubishi Chem Ind Ltd 球状シリカゲルの製造方法
JPS62283833A (ja) * 1986-06-02 1987-12-09 Seiko Epson Corp ガラス管の製造方法
JPH02225328A (ja) * 1989-02-23 1990-09-07 Nippon Muki Kk 球状シリカガラスの製造方法
US5540834A (en) * 1994-08-23 1996-07-30 Regents Of The University Of Minnesota Synthesis of porous inorganic particles by polymerization-induced colloid aggregation (PICA)
EP1298097A1 (en) * 1996-12-26 2003-04-02 MERCK PATENT GmbH Method for producing porous inorganic materials
JPH1135315A (ja) * 1997-07-18 1999-02-09 Toyota Central Res & Dev Lab Inc 高密度メソ多孔体の製造方法
JPH11147709A (ja) * 1997-11-13 1999-06-02 Tokuyama Corp 粒状シリカの製造方法
GB0315012D0 (en) 2003-06-27 2003-07-30 Leuven K U Res & Dev Zeotiles
GB0420016D0 (en) 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
US20070224133A1 (en) * 2006-03-23 2007-09-27 Mcgill Patrick D High-cleaning silica materials made via product morphology control under high shear conditions
JP4830046B1 (ja) * 2010-11-24 2011-12-07 株式会社Ｒｅｉメディカル モノリス多孔体の製造方法
CA2836782A1 (en) * 2011-05-13 2012-11-22 Mario Maio Process for producing inorganic particulate material
JP6004528B2 (ja) * 2011-08-29 2016-10-12 地方独立行政法人東京都立産業技術研究センター 多孔質シリカ内包粒子の製造方法および多孔質シリカ
JP5673957B2 (ja) * 2011-10-27 2015-02-18 日産化学工業株式会社 多孔質２次凝集シリカゾル及びその製造方法
EP2916829B1 (en) * 2012-11-12 2019-02-27 Merck Patent GmbH Use of silicon oxide-based material for the modified release of biologically active agents

Also Published As

Publication number Publication date
IL245692A0 (en) 2016-06-30
EP3074344B1 (en) 2020-02-12
US20160374943A1 (en) 2016-12-29
WO2015078552A1 (en) 2015-06-04
AU2014356854B2 (en) 2017-11-16
CA2931362A1 (en) 2015-06-04
KR20160089504A (ko) 2016-07-27
HK1222165A1 (zh) 2017-06-23
AU2014356854A1 (en) 2016-07-14
CN105764852A (zh) 2016-07-13
MX2016006738A (es) 2016-08-12
EP3074344A1 (en) 2016-10-05
JP2016539903A (ja) 2016-12-22

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