MX2013005391A - Composicion que comprende peptido inhibidor de neuraminidasa viral. - Google Patents

Composicion que comprende peptido inhibidor de neuraminidasa viral.

Info

Publication number
MX2013005391A
MX2013005391A MX2013005391A MX2013005391A MX2013005391A MX 2013005391 A MX2013005391 A MX 2013005391A MX 2013005391 A MX2013005391 A MX 2013005391A MX 2013005391 A MX2013005391 A MX 2013005391A MX 2013005391 A MX2013005391 A MX 2013005391A
Authority
MX
Mexico
Prior art keywords
peptide
inhibitor
composition
viral neuraminidase
natural
Prior art date
Application number
MX2013005391A
Other languages
English (en)
Inventor
Rudolf Lucas
Bernhard Fischer
Hendrik Fischer
Original Assignee
Apeptico Forschung & Entwicklung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apeptico Forschung & Entwicklung Gmbh filed Critical Apeptico Forschung & Entwicklung Gmbh
Publication of MX2013005391A publication Critical patent/MX2013005391A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe una composición que comprende - un péptido que consiste de 7-17 aminoácidos adyacentes y comprende el hexámero TX1EX2X3E, donde X1, X2 y X3 pueden ser cualquier aminoácido natural o no natural, y el péptido se cicliza y no exhibe actividad de enlace del receptor TNF, y - un inhibidor de neuraminidasa viral.
MX2013005391A 2010-11-18 2011-11-15 Composicion que comprende peptido inhibidor de neuraminidasa viral. MX2013005391A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA1908/2010A AT510585B1 (de) 2010-11-18 2010-11-18 Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
PCT/AT2011/000462 WO2012065201A1 (de) 2010-11-18 2011-11-15 Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase

Publications (1)

Publication Number Publication Date
MX2013005391A true MX2013005391A (es) 2013-07-29

Family

ID=45001564

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005391A MX2013005391A (es) 2010-11-18 2011-11-15 Composicion que comprende peptido inhibidor de neuraminidasa viral.

Country Status (14)

Country Link
US (2) US10344055B2 (es)
EP (1) EP2640410B1 (es)
JP (1) JP5970465B2 (es)
KR (1) KR101872218B1 (es)
CN (2) CN103200955A (es)
AT (1) AT510585B1 (es)
AU (1) AU2011331891A1 (es)
BR (1) BR112013011076A2 (es)
CA (1) CA2817787C (es)
DK (1) DK2640410T3 (es)
ES (1) ES2525758T3 (es)
MX (1) MX2013005391A (es)
RU (1) RU2596785C2 (es)
WO (1) WO2012065201A1 (es)

Families Citing this family (8)

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US9788539B2 (en) 2011-05-17 2017-10-17 Velico Medical, Inc. Platelet protection solution having beta-galactosidase and sialidase inhibitors
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
CA2887083A1 (en) 2012-10-05 2014-04-10 Velico Medical, Inc. Platelet additive solution having a beta-galactosidase inhibitor
AU2014257679A1 (en) * 2013-04-23 2015-10-15 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1 -GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
AU2014257678A1 (en) * 2013-04-23 2015-10-15 Apeptico Forschung Und Entwicklung Gmbh Lyophilisate containing a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2
KR20230038600A (ko) * 2014-03-04 2023-03-20 아펩티코 포어슝 운트 엔트빅크룽 게엠베하 폐내 염증의 완화
CN106456707B (zh) * 2014-03-18 2020-08-11 阿佩普蒂科研究和开发有限责任公司 干粉肽药剂
ES2938574T3 (es) 2020-05-08 2023-04-12 Apeptico Forschung & Entwicklung Gmbh Péptido para la prevención o el tratamiento de la COVID-19

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JPS60243016A (ja) * 1984-05-17 1985-12-03 Tsumura Juntendo Inc 抗インフルエンザウイルス剤
IT1228459B (it) 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
CZ288492B6 (en) 1990-04-24 2001-06-13 Biota Scient Management Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon
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US6419934B1 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick TNF modulators for treating neurological disorders associated with viral infection
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ES2263643T3 (es) 2000-07-28 2006-12-16 Immupharm Aps Uso de hidroxietilrutosidos para el tratamiento de los sintomas del r esfriado comun, de la fiebre de heno y de infecciones relacionadas con el tacto respiratorio.
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Also Published As

Publication number Publication date
BR112013011076A2 (pt) 2017-06-20
JP2014501718A (ja) 2014-01-23
US10344055B2 (en) 2019-07-09
CN103200955A (zh) 2013-07-10
AT510585B1 (de) 2012-05-15
CN112717122A (zh) 2021-04-30
US20190309021A1 (en) 2019-10-10
RU2013127402A (ru) 2014-12-27
EP2640410A1 (de) 2013-09-25
KR20130139966A (ko) 2013-12-23
AT510585A4 (de) 2012-05-15
ES2525758T3 (es) 2014-12-30
AU2011331891A1 (en) 2013-04-11
CA2817787C (en) 2019-03-05
WO2012065201A1 (de) 2012-05-24
RU2596785C2 (ru) 2016-09-10
CA2817787A1 (en) 2012-05-24
JP5970465B2 (ja) 2016-08-17
EP2640410B1 (de) 2014-10-29
KR101872218B1 (ko) 2018-06-28
US20130261048A1 (en) 2013-10-03
DK2640410T3 (da) 2014-11-10

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