MX2012011333A - Usos de inhibidores de dgat1. - Google Patents
Usos de inhibidores de dgat1.Info
- Publication number
- MX2012011333A MX2012011333A MX2012011333A MX2012011333A MX2012011333A MX 2012011333 A MX2012011333 A MX 2012011333A MX 2012011333 A MX2012011333 A MX 2012011333A MX 2012011333 A MX2012011333 A MX 2012011333A MX 2012011333 A MX2012011333 A MX 2012011333A
- Authority
- MX
- Mexico
- Prior art keywords
- group
- phenyl
- dgat1
- inhibitor
- substituted
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
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- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31881410P | 2010-03-30 | 2010-03-30 | |
| PCT/US2011/030234 WO2011123401A1 (en) | 2010-03-30 | 2011-03-29 | Uses of dgat1 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012011333A true MX2012011333A (es) | 2012-11-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012011333A MX2012011333A (es) | 2010-03-30 | 2011-03-29 | Usos de inhibidores de dgat1. |
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| EP (1) | EP2552441B1 (enExample) |
| JP (2) | JP2013523746A (enExample) |
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| CN (1) | CN102834099B (enExample) |
| AU (1) | AU2011235301B2 (enExample) |
| BR (1) | BR112012024618A2 (enExample) |
| CA (1) | CA2792269A1 (enExample) |
| CL (1) | CL2012002716A1 (enExample) |
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| MA (1) | MA34097B1 (enExample) |
| MX (1) | MX2012011333A (enExample) |
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| PH (1) | PH12012501859A1 (enExample) |
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| TW (1) | TW201136916A (enExample) |
| WO (1) | WO2011123401A1 (enExample) |
| ZA (1) | ZA201206456B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AR083417A1 (es) * | 2010-10-14 | 2013-02-21 | Novartis Ag | Composiciones farmaceuticas que contienen un dgat1 inhibidor |
| KR101472279B1 (ko) * | 2012-04-25 | 2014-12-16 | 한국화학연구원 | 신규한 베타 알라닌 유도체, 약학적으로 허용가능한 염 및 이를 유효성분으로 함유하는 약제학적 조성물 |
| WO2013169648A1 (en) | 2012-05-07 | 2013-11-14 | Novartis Ag | Pharmaceutical combinations comprising a dgat1 inhibtor and a triglyceride lowering drug |
| KR20200123263A (ko) * | 2013-02-14 | 2020-10-28 | 아이오니스 파마수티컬즈, 인코포레이티드 | 지질단백질 리파제 결핍 (lpld) 모집단에서 아포지질단백질 c-iii (apociii) 발현의 조절 |
| PE20152002A1 (es) | 2013-05-01 | 2016-01-21 | Isis Pharmaceuticals Inc | Composiciones y metodos para modular la expresion de ttr y vhb |
| DK3119384T3 (en) | 2014-03-20 | 2018-12-03 | Cymabay Therapeutics Inc | TREATMENT OF INTRAHEPATHIC COLESTASTIC DISEASES |
| US10272058B2 (en) | 2014-03-20 | 2019-04-30 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| CN106470675A (zh) * | 2014-06-26 | 2017-03-01 | 西玛贝医药公司 | 严重高甘油三酯血症的治疗 |
| US20180125816A1 (en) | 2015-05-11 | 2018-05-10 | Cadila Healthcare Limited | Saroglitazar magnesium for the treatment of chylomicronemia syndrome |
| US10385017B2 (en) | 2015-10-14 | 2019-08-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
| WO2019160882A1 (en) | 2018-02-13 | 2019-08-22 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| CA3093970A1 (en) * | 2018-03-16 | 2019-09-19 | Anji Pharmaceuticals Inc. | Compositions and methods for treating severe constipation |
| WO2019204609A1 (en) | 2018-04-19 | 2019-10-24 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| BR112020026746A2 (pt) | 2018-07-13 | 2021-03-30 | Gilead Sciences, Inc. | Composto, composição farmacêutica, métodos para inibir pd-1, pd-l1 e/ou a interação de pd-1/pd-l1 e para tratar câncer, e, kit para tratar ou prevenir câncer ou uma doença ou condição. |
| CN112955435B (zh) | 2018-10-24 | 2024-09-06 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
| CN113365643A (zh) * | 2018-11-30 | 2021-09-07 | Hdl治疗公司 | 用于治疗包括黄色瘤、颈动脉狭窄和脑动脉粥样硬化的脂质相关疾病的方法 |
| JP2021001143A (ja) * | 2019-06-21 | 2021-01-07 | 小林製薬株式会社 | 乳び血漿改善剤 |
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| AU3225997A (en) | 1996-05-30 | 1998-01-05 | Trustees Of Columbia University In The City Of New York, The | Dna encoding acylcoenzyme a: cholesterol acyltransferase and uses thereof |
| US6344548B1 (en) | 1998-06-24 | 2002-02-05 | The Regents Of The University Of California | Diacylglycerol o-acyltransferase |
| US20030154504A1 (en) | 1998-06-24 | 2003-08-14 | Farese Robert V. | Methods and compositions for modulating carbohydrate metabolism |
| US20030167483A1 (en) | 1998-06-24 | 2003-09-04 | Farese Robert V. | Diacylglycerol O-acyltransferase |
| DE69939426D1 (de) | 1998-06-24 | 2008-10-09 | David Gladstone Inst | Diacylglycerin o-acyltransferase |
| US6100077A (en) | 1998-10-01 | 2000-08-08 | The Trustees Of Columbia University In The City Of New York | Isolation of a gene encoding diacylglycerol acyltransferase |
| US6444427B1 (en) | 2000-07-11 | 2002-09-03 | The Regents Of The University Of California | Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof |
| JP4164645B2 (ja) | 2002-08-09 | 2008-10-15 | 株式会社大塚製薬工場 | Ｄｇａｔ阻害剤 |
| AU2003293006A1 (en) | 2002-11-22 | 2004-06-18 | Japan Tobacco Inc. | Fused bicyclic nitrogen-containing heterocycles |
| US20040185559A1 (en) | 2003-03-21 | 2004-09-23 | Isis Pharmaceuticals Inc. | Modulation of diacylglycerol acyltransferase 1 expression |
| AR044152A1 (es) | 2003-05-09 | 2005-08-24 | Bayer Corp | Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad |
| DE10331202A1 (de) * | 2003-07-10 | 2005-03-31 | S.K. Enterprise Gmbh | Verwendung von Molkenpermeat zur Behandlung des Metabolischen Syndroms |
| EP1653969A4 (en) | 2003-08-07 | 2006-12-20 | Japan Tobacco Inc | PYRROLO 1,2-B PYRIDAZINE DERIVATIVES |
| GB0325192D0 (en) | 2003-10-29 | 2003-12-03 | Astrazeneca Ab | Method of use |
| JP2005206492A (ja) | 2004-01-21 | 2005-08-04 | Sankyo Co Ltd | スルホンアミド化合物 |
| KR20060114376A (ko) | 2004-01-30 | 2006-11-06 | 니뽄 다바코 산교 가부시키가이샤 | 식욕 감퇴 화합물 |
| JP2006045209A (ja) | 2004-07-02 | 2006-02-16 | Sankyo Co Ltd | ウレア誘導体 |
| TW200606137A (en) | 2004-07-02 | 2006-02-16 | Sankyo Co | Urea derivatives |
| WO2006019020A1 (ja) | 2004-08-16 | 2006-02-23 | Sankyo Company, Limited | 置換されたウレア化合物 |
| MX2007004217A (es) | 2004-10-15 | 2007-06-11 | Bayer Pharmaceuticals Corp | Preparacion y uso de derivados de acido bifenil-4-il-carbonilamino para el tratamiento de obesidad. |
| MX2007007101A (es) | 2004-12-14 | 2007-08-21 | Astrazeneca Ab | Derivados de oxadiazol como inhibidores de acil coa:diacilglicerol aciltransferasa. |
| JP2006166742A (ja) * | 2004-12-14 | 2006-06-29 | Japan Health Science Foundation | 高トリグリセリド血症の成因となる２種類のリポタンパクリパーゼ（ｌｐｌ）遺伝子変異及びそれを利用した高トリグリセリド血症を診断するためのｌｐｌ変異検出キット |
| WO2007126957A2 (en) * | 2006-03-31 | 2007-11-08 | Novartis Ag | New compounds |
| AR066169A1 (es) | 2007-09-28 | 2009-07-29 | Novartis Ag | Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat |
| CA2719721C (en) * | 2008-03-26 | 2012-12-18 | Daiichi Sankyo Company, Limited | Tetrahydroisoquinoline derivative |
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2011
- 2011-03-29 MA MA35264A patent/MA34097B1/fr unknown
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- 2011-03-29 PH PH1/2012/501859A patent/PH12012501859A1/en unknown
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- 2011-03-29 CA CA2792269A patent/CA2792269A1/en not_active Abandoned
- 2011-03-29 BR BR112012024618A patent/BR112012024618A2/pt not_active IP Right Cessation
- 2011-03-29 NZ NZ602125A patent/NZ602125A/en not_active IP Right Cessation
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- 2011-03-29 SG SG2012063848A patent/SG183529A1/en unknown
- 2011-03-29 CN CN201180016229.9A patent/CN102834099B/zh not_active Expired - Fee Related
- 2011-03-29 ES ES11715329.6T patent/ES2586127T3/es active Active
- 2011-03-29 TW TW100110831A patent/TW201136916A/zh unknown
- 2011-03-29 WO PCT/US2011/030234 patent/WO2011123401A1/en not_active Ceased
- 2011-03-29 RU RU2012145950/15A patent/RU2012145950A/ru not_active Application Discontinuation
- 2011-03-29 KR KR1020127028214A patent/KR20130073884A/ko not_active Withdrawn
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2012
- 2012-08-28 ZA ZA2012/06456A patent/ZA201206456B/en unknown
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- 2012-09-28 CL CL2012002716A patent/CL2012002716A1/es unknown
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2016
- 2016-06-08 JP JP2016114803A patent/JP6251321B2/ja active Active
Also Published As
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| CN102834099A (zh) | 2012-12-19 |
| US20130023495A1 (en) | 2013-01-24 |
| WO2011123401A1 (en) | 2011-10-06 |
| PH12012501859A1 (en) | 2013-01-07 |
| CN102834099B (zh) | 2015-05-27 |
| NZ602125A (en) | 2014-01-31 |
| KR20130073884A (ko) | 2013-07-03 |
| CL2012002716A1 (es) | 2013-01-25 |
| ES2586127T3 (es) | 2016-10-11 |
| EP2552441B1 (en) | 2016-05-04 |
| SG183529A1 (en) | 2012-10-30 |
| BR112012024618A2 (pt) | 2019-09-24 |
| JP6251321B2 (ja) | 2017-12-20 |
| JP2013523746A (ja) | 2013-06-17 |
| AU2011235301B2 (en) | 2013-07-18 |
| MA34097B1 (fr) | 2013-03-05 |
| ZA201206456B (en) | 2013-05-29 |
| TN2012000458A1 (en) | 2014-01-30 |
| AU2011235301A1 (en) | 2012-10-11 |
| JP2016216466A (ja) | 2016-12-22 |
| TW201136916A (en) | 2011-11-01 |
| US9061012B2 (en) | 2015-06-23 |
| EP2552441A1 (en) | 2013-02-06 |
| RU2012145950A (ru) | 2014-05-10 |
| CA2792269A1 (en) | 2011-10-06 |
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