MX2012000278A - Procedimiento para la preparacion de acidos (2,4-dimetilbifenil-3- il)aceticos, sus esteres, asi como compuestos intermedios. - Google Patents

Procedimiento para la preparacion de acidos (2,4-dimetilbifenil-3- il)aceticos, sus esteres, asi como compuestos intermedios.

Info

Publication number
MX2012000278A
MX2012000278A MX2012000278A MX2012000278A MX2012000278A MX 2012000278 A MX2012000278 A MX 2012000278A MX 2012000278 A MX2012000278 A MX 2012000278A MX 2012000278 A MX2012000278 A MX 2012000278A MX 2012000278 A MX2012000278 A MX 2012000278A
Authority
MX
Mexico
Prior art keywords
dimethylbiphenyl
esters
producing
acetic acids
intermediate compounds
Prior art date
Application number
MX2012000278A
Other languages
English (en)
Inventor
Reiner Fischer
Thomas Himmler
Wolfgang Joerges
Werner Lindner
Wahed Ahmed Moradi
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2012000278A publication Critical patent/MX2012000278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

La presente invención se refiere a un nuevo procedimiento para la preparación de ácidos (2,4-dimetilbifenil-3-il)acéticos sustituidos y sin sustituir y sus ésteres de fórmula (I) usando catalizadores de paladio homogéneos y heterogéneos, así como a los productos intermedios ácido 4-terc-butil-2,6-dimetilfenilacéti co y ácido 4-terc-butil-2,6-dimetilmandélico y a procedimientos para su preparación.
MX2012000278A 2009-07-07 2010-06-25 Procedimiento para la preparacion de acidos (2,4-dimetilbifenil-3- il)aceticos, sus esteres, asi como compuestos intermedios. MX2012000278A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09164792 2009-07-07
PCT/EP2010/003911 WO2011003530A2 (de) 2009-07-07 2010-06-25 Verfahren zur herstellung von (2,4-dimethylbiphenyl-3-yl)essigsäuren, deren ester sowie zwischenverbindungen

Publications (1)

Publication Number Publication Date
MX2012000278A true MX2012000278A (es) 2012-01-27

Family

ID=41361343

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012000278A MX2012000278A (es) 2009-07-07 2010-06-25 Procedimiento para la preparacion de acidos (2,4-dimetilbifenil-3- il)aceticos, sus esteres, asi como compuestos intermedios.

Country Status (11)

Country Link
US (1) US8664428B2 (es)
EP (1) EP2451767B1 (es)
JP (2) JP6081797B2 (es)
KR (1) KR101715047B1 (es)
CN (3) CN107266306A (es)
BR (1) BR112012000244B1 (es)
DK (1) DK2451767T3 (es)
ES (1) ES2751974T3 (es)
IL (1) IL217134A (es)
MX (1) MX2012000278A (es)
WO (1) WO2011003530A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101751249B1 (ko) * 2009-08-31 2017-06-27 바이엘 인텔렉쳐 프로퍼티 게엠베하 테트라아릴보레이트를 사용한 치환된 비페닐의 제조 방법
FR3013351B1 (fr) * 2013-11-15 2016-01-01 Rhodia Operations Procede de preparation de compose aromatique mandelique et de compose aldehyde aromatique
EP3424927B1 (en) * 2017-07-04 2019-04-17 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Efficient process for the preparation of sitagliptin through a very effective preparation of the intermediate 2,4,5-trifluorophenylacetic acid
WO2019197232A1 (de) 2018-04-10 2019-10-17 Bayer Aktiengesellschaft Verfahren zur herstellung von 2,6-dialkylphenyl-essigsäuren

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860169A (en) 1953-03-25 1958-11-11 California Research Corp Process for producing 1, 2, 3-trialkylbenzenes by alkyl transfer reactions
JPS56169635A (en) * 1980-06-03 1981-12-26 Nippon Chemiphar Co Ltd Halohydrin derivative and its preparation
FR2686876B1 (fr) 1992-02-04 1994-05-13 Hoechst Ste Francaise Procede de preparation d'acides arylacetiques et de leurs sels de metaux alcalins.
DE59610095D1 (de) 1995-06-30 2003-03-06 Bayer Cropscience Ag Dialkyl-halogenphenylsubstituierte ketoenole zur verwendung als herbizide und pestizide
WO1997036868A1 (de) * 1996-04-02 1997-10-09 Bayer Aktiengesellschaft Substituierte phenylketoenole als schädlingsbekämpfungsmittel und herbizide
US5945567A (en) * 1997-08-20 1999-08-31 American Cyanamid Company Fungicidal 2-methoxybenzophenones
DE19813354A1 (de) * 1998-03-26 1999-09-30 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
EP1186583A1 (de) 2000-09-07 2002-03-13 Degussa AG Verfahren zur Durchführung von CC-Kupplungsreaktionen
JP2005529852A (ja) * 2002-03-08 2005-10-06 ビクロン・フアーマシユーチカルズ・インコーポレーテツド ラモプラニン−様アミド誘導体の製造法
DE10301804A1 (de) 2003-01-20 2004-07-29 Bayer Cropscience Ag 2,4-Dihalogen-6-(C2-C3-alkyl)-phenyl substituierte Tetramsäure-Derivate
DE10337497A1 (de) 2003-08-14 2005-03-10 Bayer Cropscience Ag 4-Biphenylsubstituierte-Pyrazolidin-3,5-dion-Derivate
AR052930A1 (es) * 2005-03-02 2007-04-11 Basf Ag Procedimiento para la preparacion de bifenilos sustituidos
EP1764365A1 (en) * 2005-09-20 2007-03-21 KRKA, D.D., Novo Mesto A process for the preparation of sartan derivates and intermediates useful in such process
DE102006057036A1 (de) 2006-12-04 2008-06-05 Bayer Cropscience Ag Biphenylsubstituierte spirocyclische Ketoenole
TW200942549A (en) 2007-12-17 2009-10-16 Janssen Pharmaceutica Nv Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1

Also Published As

Publication number Publication date
BR112012000244B1 (pt) 2019-01-08
KR20120037004A (ko) 2012-04-18
CN107266306A (zh) 2017-10-20
EP2451767B1 (de) 2019-08-21
KR101715047B1 (ko) 2017-03-10
JP2012532158A (ja) 2012-12-13
CN103980109A (zh) 2014-08-13
DK2451767T3 (da) 2019-11-11
US20120116118A1 (en) 2012-05-10
EP2451767A2 (de) 2012-05-16
BR112012000244A2 (pt) 2016-02-16
CN102471215B (zh) 2014-06-11
WO2011003530A3 (de) 2011-03-17
WO2011003530A8 (de) 2012-01-12
US8664428B2 (en) 2014-03-04
ES2751974T3 (es) 2020-04-02
IL217134A (en) 2014-11-30
CN102471215A (zh) 2012-05-23
IL217134A0 (en) 2012-02-29
JP2016040296A (ja) 2016-03-24
WO2011003530A2 (de) 2011-01-13
JP6081797B2 (ja) 2017-02-15
CN103980109B (zh) 2017-05-03

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