MX2011013541A - Agente terapeutico para la hipertension o de la presion sanguinea normal elevada. - Google Patents

Agente terapeutico para la hipertension o de la presion sanguinea normal elevada.

Info

Publication number
MX2011013541A
MX2011013541A MX2011013541A MX2011013541A MX2011013541A MX 2011013541 A MX2011013541 A MX 2011013541A MX 2011013541 A MX2011013541 A MX 2011013541A MX 2011013541 A MX2011013541 A MX 2011013541A MX 2011013541 A MX2011013541 A MX 2011013541A
Authority
MX
Mexico
Prior art keywords
blood pressure
hypertension
high blood
normal high
pharmaceutically acceptable
Prior art date
Application number
MX2011013541A
Other languages
English (en)
Inventor
Takashi Shirakura
Mizuho Tamura
Yoshimasa Takahashi
Ippei Kuwahara
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Publication of MX2011013541A publication Critical patent/MX2011013541A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se divulga un agente terapéutico o un agente profiláctico para la hipertensión o la presión sanguínea elevada normal, que comprende los componentes siguientes (a) y (b) como ingredientes activos. (a) Un compuesto de 2-feniltiazol representado por la fórmula (I) o una sal farmacéuticamente aceptable del mismo. (b) Por lo menos un compuesto seleccionado dentro del grupo que consiste de un antagonista del calcio, un inhibidor de renina-angiotensina, un agente diurético, un inhibidor de nervio simpático, un agente vasodilatador, y sales farmacéuticamente aceptables de ellos, o una sal farmacéuticamente aceptable del compuesto. Se divulga también un método para el tratamiento o la prevención de la hipertensión o de la presión sanguínea elevada normal, que comprende la administración de los componentes (a) y (b) en cantidades efectivas para el tratamiento o la prevención de la hipertensión o de la presión sanguínea elevada normal.
MX2011013541A 2009-06-26 2010-06-25 Agente terapeutico para la hipertension o de la presion sanguinea normal elevada. MX2011013541A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22071709P 2009-06-26 2009-06-26
PCT/JP2010/061301 WO2010150921A1 (ja) 2009-06-26 2010-06-25 高血圧症または正常高値血圧症の治療薬

Publications (1)

Publication Number Publication Date
MX2011013541A true MX2011013541A (es) 2012-02-21

Family

ID=43386687

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011013541A MX2011013541A (es) 2009-06-26 2010-06-25 Agente terapeutico para la hipertension o de la presion sanguinea normal elevada.

Country Status (13)

Country Link
US (1) US9545445B2 (es)
EP (1) EP2446885B1 (es)
JP (1) JP5753082B2 (es)
KR (1) KR20120096920A (es)
CN (1) CN102458401B (es)
AU (1) AU2010263549B2 (es)
BR (1) BRPI1011456A2 (es)
CA (1) CA2764597A1 (es)
HK (1) HK1170665A1 (es)
MX (1) MX2011013541A (es)
RU (1) RU2539382C2 (es)
TW (1) TW201113019A (es)
WO (1) WO2010150921A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR081935A1 (es) * 2010-06-16 2012-10-31 Teijin Pharma Ltd Tableta con nucleo recubierto de liberacion controlada
KR101710441B1 (ko) 2015-12-28 2017-02-28 신풍제약주식회사 안정성 및 용출성이 향상된 정제
CN112341467B (zh) * 2020-11-13 2022-09-27 中国科学院海洋研究所 一种二酮哌嗪生物碱类化合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE142494T1 (de) 1990-11-30 1996-09-15 Teijin Ltd 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel
US6224474B1 (en) * 1999-01-06 2001-05-01 Buehler, Ltd. Magnetic disc system for grinding or polishing specimens
DE60137635D1 (de) * 2000-06-28 2009-03-26 Merck & Co Inc Verwendung von allopurinol zur behandlung von bluthochdruck
EP1940397A4 (en) 2005-08-03 2010-01-20 Takeda Pharmaceuticals North A METHOD FOR TREATING HYPERTONIA
US20080227980A1 (en) 2005-08-05 2008-09-18 Novartis Ag Preparation of a 7H-Pyrrolo [2,3-D] Pyrimidine Derivative
WO2008143262A1 (ja) * 2007-05-21 2008-11-27 Takeda Pharmaceutical Company Limited 複素環化合物およびその用途

Also Published As

Publication number Publication date
EP2446885A1 (en) 2012-05-02
CN102458401A (zh) 2012-05-16
RU2012102518A (ru) 2013-08-10
WO2010150921A1 (ja) 2010-12-29
JPWO2010150921A1 (ja) 2012-12-10
EP2446885B1 (en) 2017-09-06
BRPI1011456A2 (pt) 2016-03-15
KR20120096920A (ko) 2012-08-31
US20110046192A1 (en) 2011-02-24
AU2010263549A1 (en) 2011-12-15
RU2539382C2 (ru) 2015-01-20
HK1170665A1 (en) 2013-03-08
EP2446885A4 (en) 2012-12-19
US9545445B2 (en) 2017-01-17
TW201113019A (en) 2011-04-16
AU2010263549B2 (en) 2014-10-30
JP5753082B2 (ja) 2015-07-22
CA2764597A1 (en) 2010-12-29
CN102458401B (zh) 2015-09-16

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