MX2011011618A - Agentes terapeuticos 713. - Google Patents
Agentes terapeuticos 713.Info
- Publication number
- MX2011011618A MX2011011618A MX2011011618A MX2011011618A MX2011011618A MX 2011011618 A MX2011011618 A MX 2011011618A MX 2011011618 A MX2011011618 A MX 2011011618A MX 2011011618 A MX2011011618 A MX 2011011618A MX 2011011618 A MX2011011618 A MX 2011011618A
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic agents
- melanin
- prophylaxis
- compounds
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
En la presente, se describen compuestos de fórmula I (ver fórmula (II)) en donde R1, R2, R3, R4, R5, A, X, Y son como se han descrito en la especificación, su uso en composiciones farmacéuticas y en métodos de tratamiento o profilaxis de una enfermedad o afección relacionada con la hormona concentradora de melanina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17463009P | 2009-05-01 | 2009-05-01 | |
PCT/GB2010/050698 WO2010125390A1 (en) | 2009-05-01 | 2010-04-29 | Therapeutic agents 713 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011011618A true MX2011011618A (es) | 2011-11-18 |
Family
ID=42290768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011011618A MX2011011618A (es) | 2009-05-01 | 2010-04-29 | Agentes terapeuticos 713. |
Country Status (23)
Country | Link |
---|---|
US (1) | US8110566B2 (es) |
EP (1) | EP2424870B1 (es) |
JP (1) | JP5763052B2 (es) |
KR (1) | KR20120023044A (es) |
CN (2) | CN102459279B (es) |
AR (1) | AR076516A1 (es) |
AU (1) | AU2010243341B2 (es) |
BR (1) | BRPI1014387A2 (es) |
CA (1) | CA2759230A1 (es) |
DK (1) | DK2424870T3 (es) |
ES (1) | ES2562831T3 (es) |
HR (1) | HRP20160128T1 (es) |
HU (1) | HUE026856T2 (es) |
MX (1) | MX2011011618A (es) |
PL (1) | PL2424870T3 (es) |
PT (1) | PT2424870E (es) |
RU (1) | RU2526055C2 (es) |
SA (1) | SA110310332B1 (es) |
SI (1) | SI2424870T1 (es) |
SM (1) | SMT201600041B (es) |
TW (1) | TW201100433A (es) |
UY (1) | UY32593A (es) |
WO (1) | WO2010125390A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010507619A (ja) * | 2006-10-25 | 2010-03-11 | ノイロサーチ アクティーゼルスカブ | オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 |
EA201291384A1 (ru) * | 2010-07-06 | 2013-07-30 | Астразенека Аб | Терапевтические агенты 976 |
UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
HU230880B1 (hu) | 2015-04-15 | 2018-11-29 | Richter Gedeon Nyrt | Indol származékok |
WO2021142395A1 (en) * | 2020-01-10 | 2021-07-15 | Consynance Therapeutics, Inc. | Therapeutic combinations of drugs and methods of using them |
HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2292931T3 (es) * | 2002-02-01 | 2008-03-16 | Novo Nordisk A/S | Amidas de azetidinas, pirrolidinas, piperidinas y azepanos aminoalquilo sustituidos. |
SE0202134D0 (sv) | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Therapeutic agents |
AU2003252715B2 (en) | 2002-07-30 | 2009-06-04 | Banyu Pharmaceutical Co., Ltd. | Antagonist of melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient |
US7601868B2 (en) | 2003-02-12 | 2009-10-13 | Takeda Pharmaceutical Company Limited | Amine derivative |
US20060293298A1 (en) * | 2003-04-10 | 2006-12-28 | Bamford Mark J | Compounds |
GB0400193D0 (en) | 2004-01-07 | 2004-02-11 | Astrazeneca Ab | Therapeutic agents |
WO2005066132A1 (en) | 2004-01-07 | 2005-07-21 | Astrazeneca Ab | Therapeutic agents i |
US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
TW200538098A (en) | 2004-03-22 | 2005-12-01 | Astrazeneca Ab | Therapeutic agents |
BRPI0513777A (pt) * | 2004-07-26 | 2008-05-13 | Lilly Co Eli | composto ou um sal do mesmo, composição farmacêutica, e, uso de um composto ou de um sal do mesmo |
EP1805169B1 (en) | 2004-10-18 | 2008-12-24 | Eli Lilly And Company | Histamine h3 receptor inhibitors, their preparation and therapeutic uses |
EP1828177B1 (en) | 2004-12-17 | 2008-08-13 | Eli Lilly And Company | Novel mch receptor antagonists |
EP1831194A4 (en) | 2004-12-21 | 2009-12-02 | Astrazeneca Ab | HETEROCYCLIC ANTAGONISTS OF MCHr1 AND THERAPEUTIC APPLICATIONS THEREOF |
JP2006176443A (ja) | 2004-12-22 | 2006-07-06 | Shionogi & Co Ltd | メラニン凝集ホルモン受容体アンタゴニスト |
WO2006130075A1 (en) | 2005-05-31 | 2006-12-07 | Astrazeneca Ab | Novel mchr1 antagonists and their use for the treatment of mchr1 mediated conditions and disorders |
WO2007011284A1 (en) | 2005-07-15 | 2007-01-25 | Astrazeneca Ab | Therapeutic agents |
CN101400677A (zh) | 2006-01-06 | 2009-04-01 | 阿斯利康(瑞典)有限公司 | 化合物 |
WO2008011453A2 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF LLβ-HSD-1 |
EP2121703A4 (en) | 2006-08-18 | 2011-12-28 | Astrazeneca Ab | THIENOPYRIMIDIN-4-ON- AND THIENOPYRIDAZIN-7-ONDERIVATES AS MCH-RL ANTAGONISTS |
WO2008068265A1 (en) | 2006-12-05 | 2008-06-12 | Janssen Pharmaceutica N.V. | Novel substituted diaza spiro pyridinone derivatives for use in mch-1 mediated diseases |
BRPI0721086A2 (pt) | 2006-12-14 | 2014-02-25 | Lilly Co Eli | Derivados de 5-[4-(azetidin-3-ilóxi)-fenil]-2-fenil-5h-tiazolo[5,4-c]piri din-4-ona e seu emprego como antago-nistas de receptor de mch |
JP2010524962A (ja) | 2007-04-17 | 2010-07-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | オーロラキナーゼ阻害剤のための創薬法 |
WO2009024502A1 (en) | 2007-08-22 | 2009-02-26 | F. Hoffmann-La Roche Ag | Pyrrolidine aryl-ether as nk3 receptor antagonists |
CA2702467C (en) * | 2007-10-17 | 2012-11-27 | Sanofi-Aventis | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof |
AU2009261248A1 (en) * | 2008-06-19 | 2009-12-23 | Banyu Pharmaceutical Co., Ltd. | Spirodiamine-diarylketoxime derivative |
-
2010
- 2010-04-28 SA SA110310332A patent/SA110310332B1/ar unknown
- 2010-04-29 HU HUE10718670A patent/HUE026856T2/en unknown
- 2010-04-29 WO PCT/GB2010/050698 patent/WO2010125390A1/en active Application Filing
- 2010-04-29 EP EP10718670.2A patent/EP2424870B1/en active Active
- 2010-04-29 RU RU2011147751/04A patent/RU2526055C2/ru not_active IP Right Cessation
- 2010-04-29 ES ES10718670.2T patent/ES2562831T3/es active Active
- 2010-04-29 PT PT107186702T patent/PT2424870E/pt unknown
- 2010-04-29 PL PL10718670T patent/PL2424870T3/pl unknown
- 2010-04-29 TW TW099113722A patent/TW201100433A/zh unknown
- 2010-04-29 CA CA2759230A patent/CA2759230A1/en not_active Abandoned
- 2010-04-29 KR KR1020117028655A patent/KR20120023044A/ko not_active Application Discontinuation
- 2010-04-29 BR BRPI1014387A patent/BRPI1014387A2/pt not_active IP Right Cessation
- 2010-04-29 CN CN201080031068.6A patent/CN102459279B/zh not_active Expired - Fee Related
- 2010-04-29 MX MX2011011618A patent/MX2011011618A/es active IP Right Grant
- 2010-04-29 CN CN201410183568.1A patent/CN103936751A/zh active Pending
- 2010-04-29 SI SI201031124T patent/SI2424870T1/sl unknown
- 2010-04-29 AU AU2010243341A patent/AU2010243341B2/en not_active Ceased
- 2010-04-29 DK DK10718670.2T patent/DK2424870T3/en active
- 2010-04-29 JP JP2012507821A patent/JP5763052B2/ja not_active Expired - Fee Related
- 2010-04-30 US US12/771,594 patent/US8110566B2/en not_active Expired - Fee Related
- 2010-04-30 AR ARP100101476A patent/AR076516A1/es not_active Application Discontinuation
- 2010-04-30 UY UY0001032593A patent/UY32593A/es not_active Application Discontinuation
-
2016
- 2016-02-04 HR HRP20160128TT patent/HRP20160128T1/hr unknown
- 2016-02-11 SM SM201600041T patent/SMT201600041B/it unknown
Also Published As
Publication number | Publication date |
---|---|
HUE026856T2 (en) | 2016-07-28 |
CN102459279B (zh) | 2014-06-25 |
DK2424870T3 (en) | 2016-02-15 |
AU2010243341B2 (en) | 2014-02-13 |
EP2424870B1 (en) | 2015-12-16 |
CN103936751A (zh) | 2014-07-23 |
UY32593A (es) | 2010-11-30 |
HRP20160128T1 (hr) | 2016-02-26 |
WO2010125390A1 (en) | 2010-11-04 |
SI2424870T1 (sl) | 2016-03-31 |
JP5763052B2 (ja) | 2015-08-12 |
BRPI1014387A2 (pt) | 2017-06-06 |
AU2010243341A1 (en) | 2011-11-03 |
RU2526055C2 (ru) | 2014-08-20 |
EP2424870A1 (en) | 2012-03-07 |
PL2424870T3 (pl) | 2016-05-31 |
PT2424870E (pt) | 2016-03-17 |
US20100280000A1 (en) | 2010-11-04 |
US8110566B2 (en) | 2012-02-07 |
SA110310332B1 (ar) | 2013-12-10 |
ES2562831T3 (es) | 2016-03-08 |
JP2012525365A (ja) | 2012-10-22 |
CN102459279A (zh) | 2012-05-16 |
SMT201600041B (it) | 2016-02-25 |
CA2759230A1 (en) | 2010-11-04 |
KR20120023044A (ko) | 2012-03-12 |
TW201100433A (en) | 2011-01-01 |
AR076516A1 (es) | 2011-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |