MX2011011217A - Metodo para mejorar el perfil de disolucion de un material biologicamente activo. - Google Patents
Metodo para mejorar el perfil de disolucion de un material biologicamente activo.Info
- Publication number
- MX2011011217A MX2011011217A MX2011011217A MX2011011217A MX2011011217A MX 2011011217 A MX2011011217 A MX 2011011217A MX 2011011217 A MX2011011217 A MX 2011011217A MX 2011011217 A MX2011011217 A MX 2011011217A MX 2011011217 A MX2011011217 A MX 2011011217A
- Authority
- MX
- Mexico
- Prior art keywords
- active material
- biologically active
- improving
- dissolution profile
- milling
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
- A01N25/14—Powders or granules wettable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Disintegrating Or Milling (AREA)
Abstract
La presente invención se refiere a un método para mejorar el perfil de disolución de un material biológicamente activo que comprende las etapas de molienda en seco de un material biológicamente activo sólido y una matriz de molienda que se puede moler en un molino que comprende una pluralidad de cuerpos de molienda, por un periodo de tiempo suficiente para producir partículas del material biológicamente activo dispersado en al menos un material de molido parcialmente molido.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17230109P | 2009-04-24 | 2009-04-24 | |
AU2009901741A AU2009901741A0 (en) | 2009-04-24 | Method for Improving the Dissolution Profile of a Biologically Active Material | |
PCT/AU2010/000465 WO2010121321A1 (en) | 2009-04-24 | 2010-04-23 | Method for improving the dissolution profile of a biologically active material |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2011011217A true MX2011011217A (es) | 2012-02-08 |
MX360545B MX360545B (es) | 2018-10-26 |
Family
ID=43010604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011011217A MX360545B (es) | 2009-04-24 | 2010-04-23 | Método para mejorar el perfil de disolución de un material biológicamente activo. |
Country Status (21)
Country | Link |
---|---|
US (5) | US20120165323A1 (es) |
EP (1) | EP2421516A4 (es) |
JP (3) | JP5898613B2 (es) |
KR (3) | KR101679522B1 (es) |
CN (3) | CN104825396A (es) |
AP (2) | AP3629A (es) |
AU (2) | AU2010239160B2 (es) |
BR (1) | BRPI1014277A2 (es) |
CA (1) | CA2759104C (es) |
CO (1) | CO6470804A2 (es) |
EA (1) | EA201171280A1 (es) |
IL (1) | IL215871B (es) |
MA (1) | MA33293B1 (es) |
MX (1) | MX360545B (es) |
MY (1) | MY163538A (es) |
NZ (1) | NZ595972A (es) |
PH (1) | PH12015501781A1 (es) |
SG (1) | SG175308A1 (es) |
UA (1) | UA110772C2 (es) |
WO (1) | WO2010121321A1 (es) |
ZA (1) | ZA201108647B (es) |
Families Citing this family (29)
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JP5508003B2 (ja) | 2006-06-30 | 2014-05-28 | アイスイティカ ピーティーワイ リミテッド | ナノ粒子状の形態における生物学的に活性な化合物の調製のための方法 |
KR101679522B1 (ko) * | 2009-04-24 | 2016-11-24 | 아이슈티카 피티와이 리미티드 | 생물학적 활성 물질의 용해 프로파일 개선방법 |
BRPI1014275B8 (pt) | 2009-04-24 | 2021-05-25 | Iceutica Pty Ltd | composição que compreende partículas de indometacina dispersas em pelo menos dois materiais de moagem parcialmente moídos |
NZ595903A (en) * | 2009-04-24 | 2014-03-28 | Iceutica Pty Ltd | A novel formulation of metaxalone |
CN102438592B (zh) * | 2009-04-24 | 2016-09-14 | 伊休蒂卡有限公司 | 甲氧萘普酸的剂型 |
EP2421509B1 (en) * | 2009-04-24 | 2017-11-22 | Iceutica Pty Ltd. | Production of encapsulated nanoparticles at high volume fractions |
BRPI1014276B8 (pt) * | 2009-04-24 | 2021-05-25 | Iceutica Pty Ltd | produção de nanopartículas encapsuladas em escala comercial |
US10369108B2 (en) * | 2013-03-15 | 2019-08-06 | Mylan Laboratories, Inc. | Hot melt granulation formulations of poorly water-soluble active agents |
US20150157646A1 (en) | 2013-09-27 | 2015-06-11 | Iceutica Inc. | Abiraterone Steroid Formulation |
CN104644556B (zh) * | 2013-11-22 | 2018-05-22 | 沈阳药科大学 | 盐酸依福地平固体粉末及其制备方法 |
AU2015200340B2 (en) * | 2014-02-05 | 2019-01-24 | Upl Limited | Combinations |
US11175268B2 (en) | 2014-06-09 | 2021-11-16 | Biometry Inc. | Mini point of care gas chromatographic test strip and method to measure analytes |
CA2951690A1 (en) | 2014-06-09 | 2015-12-17 | Biometry Inc. | Low cost test strip and method to measure analyte |
US9526734B2 (en) | 2014-06-09 | 2016-12-27 | Iceutica Pty Ltd. | Formulation of meloxicam |
CA2988918A1 (en) * | 2015-06-19 | 2016-12-22 | Biotie Therapies, Inc. | Controlled-release tozadenant formulations |
JP6968062B6 (ja) * | 2015-10-23 | 2021-12-15 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 発香性物質及び香味物質とビニルラクタムポリマーとの固溶体 |
CN105385739B (zh) * | 2015-12-09 | 2017-09-29 | 梁尚文 | -种从金边蚂蟥中制取蛋白肽的方法 |
CN109715067B (zh) | 2016-07-19 | 2022-05-17 | 生物统计股份有限公司 | 使用批量可校准测试条测量分析物的方法和系统 |
CN107853670A (zh) * | 2017-10-30 | 2018-03-30 | 潍坊友容实业有限公司 | 一种盐地碱蓬生物盐提取方法 |
CN108379238B (zh) * | 2018-01-17 | 2020-07-14 | 南昌大学 | 一种储存物理稳定性好的环孢素固体脂质纳米粒及其制备方法 |
CN116327960A (zh) | 2018-05-11 | 2023-06-27 | 南京清普生物科技有限公司 | 一种美洛昔康组合物、制剂及其制备方法与应用 |
AU2019332696A1 (en) * | 2018-08-31 | 2021-03-18 | Kemin Industries, Inc. | Technology for water dispersible phospholipids and lysophospholipids |
US20210338613A1 (en) * | 2018-10-05 | 2021-11-04 | Dyve Biosciences, Inc. | Formulations and methods for transdermal administration of ketones |
US11197830B2 (en) | 2019-02-27 | 2021-12-14 | Aft Pharmaceuticals Limited | Pharmaceutical composition containing acetaminophen and ibuprofen |
CN113133970A (zh) * | 2020-01-17 | 2021-07-20 | 美国琛蓝营养制品股份有限公司 | 一种姜黄素复合物及其制备方法和检测方法 |
TR202017034A2 (tr) * | 2020-10-26 | 2021-09-21 | Hacettepe Ueniversitesi Rektoerluek | Kuru öğütme yöntemi̇ i̇le hazirlanan ve çözünme hizi arttirilmiş selekoksi̇b i̇çeren farmasöti̇k kompozi̇syonlar |
CN114306253B (zh) * | 2021-11-16 | 2023-08-22 | 扬子江药业集团广州海瑞药业有限公司 | 格列美脲片剂及其制备方法 |
CN113996161B (zh) * | 2021-12-30 | 2022-04-19 | 河北鑫鹏新材料科技有限公司 | 一种硫转移剂及其制备方法和应用 |
CN114732009B (zh) * | 2022-06-13 | 2022-08-23 | 山东百农思达生物科技有限公司 | 一种含有吡唑醚菌酯和烯酰吗啉的水分散粒剂的制备方法 |
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JP2642486B2 (ja) * | 1989-08-04 | 1997-08-20 | 田辺製薬株式会社 | 難溶性薬物の超微粒子化法 |
AU660852B2 (en) * | 1992-11-25 | 1995-07-06 | Elan Pharma International Limited | Method of grinding pharmaceutical substances |
JP4117811B2 (ja) * | 1997-04-22 | 2008-07-16 | 日本化薬株式会社 | フルタミド製剤及びその製法 |
SA99191255B1 (ar) * | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
ATE424811T1 (de) * | 2000-08-31 | 2009-03-15 | Jagotec Ag | Gemahlene partikel |
JP2004099442A (ja) * | 2002-09-04 | 2004-04-02 | Nisshin Pharma Inc | 難溶性薬物含有製剤およびその製造方法 |
US20090028948A1 (en) * | 2004-12-31 | 2009-01-29 | Iceutica Pty Ltd | Nanoparticle composition and methods of synthesis thereof |
WO2007070852A2 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for parenteral administration |
EP1973523A2 (en) * | 2005-12-15 | 2008-10-01 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
US8808751B2 (en) * | 2006-06-30 | 2014-08-19 | Iceutica Pty Ltd. | Methods for the preparation of biologically active compounds in nanoparticulate form |
JP5508003B2 (ja) * | 2006-06-30 | 2014-05-28 | アイスイティカ ピーティーワイ リミテッド | ナノ粒子状の形態における生物学的に活性な化合物の調製のための方法 |
BRPI1014275B8 (pt) * | 2009-04-24 | 2021-05-25 | Iceutica Pty Ltd | composição que compreende partículas de indometacina dispersas em pelo menos dois materiais de moagem parcialmente moídos |
CN102438610A (zh) * | 2009-04-24 | 2012-05-02 | 伊休蒂卡有限公司 | 双氯芬酸的新剂型 |
KR101679522B1 (ko) * | 2009-04-24 | 2016-11-24 | 아이슈티카 피티와이 리미티드 | 생물학적 활성 물질의 용해 프로파일 개선방법 |
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2010
- 2010-04-23 KR KR1020157001083A patent/KR101679522B1/ko active IP Right Grant
- 2010-04-23 MY MYPI2011005117A patent/MY163538A/en unknown
- 2010-04-23 EP EP10766514A patent/EP2421516A4/en not_active Withdrawn
- 2010-04-23 MX MX2011011217A patent/MX360545B/es active IP Right Grant
- 2010-04-23 MA MA34379A patent/MA33293B1/fr unknown
- 2010-04-23 CN CN201510169316.8A patent/CN104825396A/zh active Pending
- 2010-04-23 CA CA2759104A patent/CA2759104C/en active Active
- 2010-04-23 CN CN201410083535.XA patent/CN103830243A/zh active Pending
- 2010-04-23 SG SG2011077344A patent/SG175308A1/en unknown
- 2010-04-23 KR KR1020117027883A patent/KR20120047207A/ko active Search and Examination
- 2010-04-23 WO PCT/AU2010/000465 patent/WO2010121321A1/en active Application Filing
- 2010-04-23 AP AP2011005994A patent/AP3629A/xx active
- 2010-04-23 AP AP2015008965A patent/AP2015008965A0/en unknown
- 2010-04-23 NZ NZ595972A patent/NZ595972A/en unknown
- 2010-04-23 UA UAA201113805A patent/UA110772C2/uk unknown
- 2010-04-23 US US13/265,927 patent/US20120165323A1/en not_active Abandoned
- 2010-04-23 KR KR1020167021933A patent/KR101873500B1/ko active IP Right Grant
- 2010-04-23 AU AU2010239160A patent/AU2010239160B2/en active Active
- 2010-04-23 EA EA201171280A patent/EA201171280A1/ru unknown
- 2010-04-23 BR BRPI1014277A patent/BRPI1014277A2/pt not_active Application Discontinuation
- 2010-04-23 CN CN2010800180042A patent/CN102438600A/zh active Pending
- 2010-04-23 JP JP2012506283A patent/JP5898613B2/ja active Active
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2011
- 2011-10-23 IL IL215871A patent/IL215871B/en active IP Right Grant
- 2011-11-23 CO CO11160573A patent/CO6470804A2/es not_active Application Discontinuation
- 2011-11-24 ZA ZA2011/08647A patent/ZA201108647B/en unknown
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2013
- 2013-06-24 US US13/925,325 patent/US20130277468A1/en not_active Abandoned
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2015
- 2015-04-22 JP JP2015087235A patent/JP2015199736A/ja active Pending
- 2015-08-12 PH PH12015501781A patent/PH12015501781A1/en unknown
- 2015-10-14 AU AU2015243003A patent/AU2015243003A1/en not_active Abandoned
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2017
- 2017-06-05 JP JP2017110518A patent/JP6619386B2/ja active Active
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2018
- 2018-01-19 US US15/875,794 patent/US20180169018A1/en not_active Abandoned
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2019
- 2019-12-17 US US16/718,105 patent/US20200375903A1/en not_active Abandoned
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2021
- 2021-09-07 US US17/468,541 patent/US20210401753A1/en active Pending
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