MX2011006534A - Dispositivo de inyeccion de dosis fija con mecanismo de accionamiento reajustable. - Google Patents
Dispositivo de inyeccion de dosis fija con mecanismo de accionamiento reajustable.Info
- Publication number
- MX2011006534A MX2011006534A MX2011006534A MX2011006534A MX2011006534A MX 2011006534 A MX2011006534 A MX 2011006534A MX 2011006534 A MX2011006534 A MX 2011006534A MX 2011006534 A MX2011006534 A MX 2011006534A MX 2011006534 A MX2011006534 A MX 2011006534A
- Authority
- MX
- Mexico
- Prior art keywords
- dose
- injection device
- housing
- piston rod
- dosing element
- Prior art date
Links
- 238000002347 injection Methods 0.000 title claims abstract description 67
- 239000007924 injection Substances 0.000 title claims abstract description 67
- 230000007246 mechanism Effects 0.000 title claims abstract description 8
- 239000003814 drug Substances 0.000 claims abstract description 22
- 230000008878 coupling Effects 0.000 claims description 71
- 238000010168 coupling process Methods 0.000 claims description 71
- 238000005859 coupling reaction Methods 0.000 claims description 71
- 238000000034 method Methods 0.000 claims description 5
- 230000004308 accommodation Effects 0.000 claims description 4
- 229940079593 drug Drugs 0.000 abstract description 11
- 238000006073 displacement reaction Methods 0.000 description 11
- 230000003993 interaction Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 108091016366 Histone-lysine N-methyltransferase EHMT1 Proteins 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 230000005226 mechanical processes and functions Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
- A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08022317A EP2201972A1 (en) | 2008-12-23 | 2008-12-23 | Fixed dose injection device with resettable drive mechanism |
| PCT/EP2009/067480 WO2010072662A1 (en) | 2008-12-23 | 2009-12-18 | Fixed dose injection device with resettable drive mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011006534A true MX2011006534A (es) | 2011-07-13 |
Family
ID=40584731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011006534A MX2011006534A (es) | 2008-12-23 | 2009-12-18 | Dispositivo de inyeccion de dosis fija con mecanismo de accionamiento reajustable. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8945069B2 (enExample) |
| EP (2) | EP2201972A1 (enExample) |
| JP (1) | JP5588998B2 (enExample) |
| KR (1) | KR20110099051A (enExample) |
| CN (1) | CN102325562B (enExample) |
| AU (1) | AU2009331633A1 (enExample) |
| CA (1) | CA2747324A1 (enExample) |
| DK (1) | DK2381984T3 (enExample) |
| IL (1) | IL213575A0 (enExample) |
| MX (1) | MX2011006534A (enExample) |
| NZ (1) | NZ593744A (enExample) |
| RU (1) | RU2514537C2 (enExample) |
| SG (1) | SG172319A1 (enExample) |
| TW (1) | TW201034712A (enExample) |
| WO (1) | WO2010072662A1 (enExample) |
| ZA (1) | ZA201103877B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9351964B2 (en) | 2009-05-27 | 2016-05-31 | Ptc Therapeutics, Inc. | Methods for treating cancer and non-neoplastic conditions |
| EP2475411B1 (en) * | 2009-09-07 | 2014-12-31 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for drug delivery device |
| EP2292286A1 (en) * | 2009-09-07 | 2011-03-09 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a medication delivery device and medication delivery device |
| EP2482889B1 (en) * | 2009-09-30 | 2016-02-10 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device |
| AR078457A1 (es) * | 2009-09-30 | 2011-11-09 | Sanofi Aventis Deutschland | Mecanismo accionador para un dispositivo de descarga de farmacos |
| JP5805092B2 (ja) | 2009-09-30 | 2015-11-04 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 注射デバイス |
| BR112012007310A2 (pt) * | 2009-09-30 | 2016-04-19 | Sanofi Aventis Deutschland | mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento |
| WO2011039205A2 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and drive member for a drug delivery device |
| GB0918145D0 (en) | 2009-10-16 | 2009-12-02 | Owen Mumford Ltd | Injector apparatus |
| EP2438950A1 (en) * | 2010-10-06 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a drug delivery device and drug delivery device |
| EP2438951A1 (en) * | 2010-10-06 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a drug delivery device and drug delivery device |
| TWI544941B (zh) * | 2010-10-06 | 2016-08-11 | 賽諾菲阿凡提斯德意志有限公司 | 藥物傳送裝置的驅動機構及藥物傳送裝置 |
| EP2438949A1 (en) | 2010-10-06 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a drug delivery device and drug delivery device |
| BR112013008617A2 (pt) | 2010-10-13 | 2016-06-14 | Sanofi Aventis Deutschland | mecanismo de ajuste de dose e método de uso do mesmo |
| CN103260675B (zh) | 2010-10-13 | 2016-01-20 | 赛诺菲-安万特德国有限公司 | 剂量设定机构和使用该剂量设定机构的方法 |
| TWI574708B (zh) * | 2011-06-17 | 2017-03-21 | 賽諾菲阿凡提斯德意志有限公司 | 用於藥物遞送裝置的卡匣支撐器總成 |
| WO2014029683A1 (en) * | 2012-08-20 | 2014-02-27 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for electrically detecting contact between piston rod and cartridge bung |
| US9486586B2 (en) * | 2012-08-20 | 2016-11-08 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for detecting a contact |
| TW201509464A (zh) | 2013-04-10 | 2015-03-16 | Sanofi Sa | 注射裝置及組裝方法 |
| SG11201600439SA (en) | 2013-08-02 | 2016-02-26 | Becton Dickinson Co | Injection pen |
| CN104436375A (zh) * | 2014-12-30 | 2015-03-25 | 江苏华阳电器有限公司 | 一种注射笔 |
| KR20200035292A (ko) | 2017-08-01 | 2020-04-02 | 피티씨 테라퓨틱스, 인크. | 혈액 암 치료에 사용하기 위한 dhodh 억제제 |
| EP3836989A1 (en) | 2018-09-08 | 2021-06-23 | Shaily Engineering Plastics Limited | Injection device |
| JP7646550B2 (ja) * | 2019-01-18 | 2025-03-17 | サノフイ | 注射デバイス |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
| GB9219849D0 (en) * | 1992-09-19 | 1992-10-28 | Hypoguard Uk Ltd | Device |
| DK170604B1 (da) * | 1993-12-07 | 1995-11-13 | Niels Erik Holm Aps | Doseringsenhed til dosering af afmålte mængder af en væske |
| UA56256C2 (uk) * | 1998-01-30 | 2003-05-15 | Ново Нордіск А/С | Шприц для ін'єкцій |
| US6936032B1 (en) * | 1999-08-05 | 2005-08-30 | Becton, Dickinson And Company | Medication delivery pen |
| GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| JP4964136B2 (ja) * | 2004-10-14 | 2012-06-27 | ノボ・ノルデイスク・エー／エス | 用量設定機構を備えた注射器 |
| BRPI0607012A2 (pt) * | 2005-01-25 | 2009-12-01 | Novo Nordisk As | dispositivo de injeção |
| WO2006114395A1 (en) * | 2005-04-24 | 2006-11-02 | Novo Nordisk A/S | An injection device with a gearbox |
| EP1923084A1 (en) * | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
-
2008
- 2008-12-23 EP EP08022317A patent/EP2201972A1/en not_active Ceased
-
2009
- 2009-12-18 JP JP2011542784A patent/JP5588998B2/ja active Active
- 2009-12-18 NZ NZ593744A patent/NZ593744A/xx not_active IP Right Cessation
- 2009-12-18 EP EP09796712.9A patent/EP2381984B1/en active Active
- 2009-12-18 SG SG2011045739A patent/SG172319A1/en unknown
- 2009-12-18 WO PCT/EP2009/067480 patent/WO2010072662A1/en not_active Ceased
- 2009-12-18 US US13/140,131 patent/US8945069B2/en active Active
- 2009-12-18 AU AU2009331633A patent/AU2009331633A1/en not_active Abandoned
- 2009-12-18 RU RU2011130897/14A patent/RU2514537C2/ru not_active IP Right Cessation
- 2009-12-18 MX MX2011006534A patent/MX2011006534A/es not_active Application Discontinuation
- 2009-12-18 CN CN200980157365.2A patent/CN102325562B/zh active Active
- 2009-12-18 KR KR1020117017368A patent/KR20110099051A/ko not_active Withdrawn
- 2009-12-18 DK DK09796712.9T patent/DK2381984T3/da active
- 2009-12-18 CA CA2747324A patent/CA2747324A1/en not_active Abandoned
- 2009-12-21 TW TW098143810A patent/TW201034712A/zh unknown
-
2011
- 2011-05-26 ZA ZA2011/03877A patent/ZA201103877B/en unknown
- 2011-06-15 IL IL213575A patent/IL213575A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1161850A1 (en) | 2012-08-10 |
| EP2381984A1 (en) | 2011-11-02 |
| ZA201103877B (en) | 2012-01-25 |
| KR20110099051A (ko) | 2011-09-05 |
| RU2514537C2 (ru) | 2014-04-27 |
| JP5588998B2 (ja) | 2014-09-10 |
| RU2011130897A (ru) | 2013-01-27 |
| IL213575A0 (en) | 2011-07-31 |
| EP2201972A1 (en) | 2010-06-30 |
| CA2747324A1 (en) | 2010-07-01 |
| AU2009331633A1 (en) | 2011-07-14 |
| EP2381984B1 (en) | 2022-05-11 |
| WO2010072662A1 (en) | 2010-07-01 |
| JP2012513266A (ja) | 2012-06-14 |
| US20120046643A1 (en) | 2012-02-23 |
| US8945069B2 (en) | 2015-02-03 |
| CN102325562A (zh) | 2012-01-18 |
| DK2381984T3 (da) | 2022-08-01 |
| NZ593744A (en) | 2013-11-29 |
| SG172319A1 (en) | 2011-07-28 |
| CN102325562B (zh) | 2014-07-16 |
| TW201034712A (en) | 2010-10-01 |
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