JP5588998B2 - 再設定可能な駆動機構を備えた固定用量注射デバイス - Google Patents

再設定可能な駆動機構を備えた固定用量注射デバイス Download PDF

Info

Publication number
JP5588998B2
JP5588998B2 JP2011542784A JP2011542784A JP5588998B2 JP 5588998 B2 JP5588998 B2 JP 5588998B2 JP 2011542784 A JP2011542784 A JP 2011542784A JP 2011542784 A JP2011542784 A JP 2011542784A JP 5588998 B2 JP5588998 B2 JP 5588998B2
Authority
JP
Japan
Prior art keywords
dose
injection device
housing
drive member
piston rod
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2011542784A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012513266A5 (enExample
JP2012513266A (ja
Inventor
デイヴィッド・プランプトリ
クリストファー・ジェイムズ・スミス
Original Assignee
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング filed Critical サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Publication of JP2012513266A publication Critical patent/JP2012513266A/ja
Publication of JP2012513266A5 publication Critical patent/JP2012513266A5/ja
Application granted granted Critical
Publication of JP5588998B2 publication Critical patent/JP5588998B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2011542784A 2008-12-23 2009-12-18 再設定可能な駆動機構を備えた固定用量注射デバイス Active JP5588998B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08022317.5 2008-12-23
EP08022317A EP2201972A1 (en) 2008-12-23 2008-12-23 Fixed dose injection device with resettable drive mechanism
PCT/EP2009/067480 WO2010072662A1 (en) 2008-12-23 2009-12-18 Fixed dose injection device with resettable drive mechanism

Publications (3)

Publication Number Publication Date
JP2012513266A JP2012513266A (ja) 2012-06-14
JP2012513266A5 JP2012513266A5 (enExample) 2013-01-31
JP5588998B2 true JP5588998B2 (ja) 2014-09-10

Family

ID=40584731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011542784A Active JP5588998B2 (ja) 2008-12-23 2009-12-18 再設定可能な駆動機構を備えた固定用量注射デバイス

Country Status (16)

Country Link
US (1) US8945069B2 (enExample)
EP (2) EP2201972A1 (enExample)
JP (1) JP5588998B2 (enExample)
KR (1) KR20110099051A (enExample)
CN (1) CN102325562B (enExample)
AU (1) AU2009331633A1 (enExample)
CA (1) CA2747324A1 (enExample)
DK (1) DK2381984T3 (enExample)
IL (1) IL213575A0 (enExample)
MX (1) MX2011006534A (enExample)
NZ (1) NZ593744A (enExample)
RU (1) RU2514537C2 (enExample)
SG (1) SG172319A1 (enExample)
TW (1) TW201034712A (enExample)
WO (1) WO2010072662A1 (enExample)
ZA (1) ZA201103877B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE052510T2 (hu) 2009-05-27 2021-05-28 Ptc Therapeutics Inc Módszerek a rák és a nem daganatos állapotok kezelésére
EP2292286A1 (en) * 2009-09-07 2011-03-09 Sanofi-Aventis Deutschland GmbH Drive mechanism for a medication delivery device and medication delivery device
DK2475411T3 (en) * 2009-09-07 2015-04-07 Sanofi Aventis Deutschland A drive mechanism for device for drug delivery
CA2773928A1 (en) 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Injection device
TW201127435A (en) * 2009-09-30 2011-08-16 Sanofi Aventis Deutschland Drive mechanism for a drug delivery device
WO2011039205A2 (en) * 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Drug delivery device and drive member for a drug delivery device
DK2482889T3 (en) * 2009-09-30 2016-05-17 Sanofi Aventis Deutschland ACCOMMODATION drug delivery device
BR112012007310A2 (pt) * 2009-09-30 2016-04-19 Sanofi Aventis Deutschland mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
EP2438951A1 (en) * 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
EP2438949A1 (en) 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
TWI544941B (zh) * 2010-10-06 2016-08-11 賽諾菲阿凡提斯德意志有限公司 藥物傳送裝置的驅動機構及藥物傳送裝置
EP2438950A1 (en) * 2010-10-06 2012-04-11 Sanofi-Aventis Deutschland GmbH Drive mechanism for a drug delivery device and drug delivery device
CN103260675B (zh) * 2010-10-13 2016-01-20 赛诺菲-安万特德国有限公司 剂量设定机构和使用该剂量设定机构的方法
CN103153371B (zh) 2010-10-13 2015-10-07 赛诺菲-安万特德国有限公司 用于药物递送装置的剂量设定机构
BR112013032089A2 (pt) * 2011-06-17 2016-12-13 Sanofi Aventis Deutschland dispositivo de aplicação de fármacos para administrar uma dose predefinida de um fármaco
CN104582765A (zh) * 2012-08-20 2015-04-29 赛诺菲-安万特德国有限公司 药物输送装置和检测接触的方法
CN104540535A (zh) * 2012-08-20 2015-04-22 赛诺菲-安万特德国有限公司 电检测活塞杆与药筒筒塞之间的接触的方法和药物输送装置
DK2983746T3 (da) * 2013-04-10 2020-03-23 Sanofi Sa Injektionsanordning og fremgangsmåde til samling
JP6480443B2 (ja) 2013-08-02 2019-03-13 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 注射ペン
CN104436375A (zh) * 2014-12-30 2015-03-25 江苏华阳电器有限公司 一种注射笔
US11458126B2 (en) 2017-08-01 2022-10-04 Ptc Therapeutics, Inc. DHODH inhibitor for use in treating hematologic cancers
ES3071319T3 (en) * 2018-09-08 2026-06-22 Shaily Engineering Plastics Ltd Injection device
US12434007B2 (en) * 2019-01-18 2025-10-07 Sanofi Injection device
AU2020280117B2 (en) * 2019-05-20 2023-04-06 The University Of Sydney An adaptor for a medicament delivery device and a related method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4475905A (en) * 1982-09-30 1984-10-09 Himmelstrup Anders B Injection device
GB9219849D0 (en) * 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
DK170604B1 (da) * 1993-12-07 1995-11-13 Niels Erik Holm Aps Doseringsenhed til dosering af afmålte mængder af en væske
JP3270761B2 (ja) * 1998-01-30 2002-04-02 ノボ ノルディスク アクティーゼルスカブ 注射器
DE60026147T2 (de) * 1999-08-05 2006-11-23 Becton, Dickinson And Co. Stiftförmige medikamentenabgabevorrichtung
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
CN101039713B (zh) * 2004-10-14 2011-10-12 诺和诺德公司 具有剂量机构的注射装置
WO2006079481A1 (en) * 2005-01-25 2006-08-03 Novo Nordisk A/S An injection device with an end of dose feedback mechanism
EP1890751A1 (en) * 2005-04-24 2008-02-27 Novo Nordisk A/S An injection device with a gearbox
EP1923084A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Dosing and drive mechanism for drug delivery device

Also Published As

Publication number Publication date
KR20110099051A (ko) 2011-09-05
NZ593744A (en) 2013-11-29
EP2381984A1 (en) 2011-11-02
CA2747324A1 (en) 2010-07-01
TW201034712A (en) 2010-10-01
EP2201972A1 (en) 2010-06-30
CN102325562B (zh) 2014-07-16
CN102325562A (zh) 2012-01-18
DK2381984T3 (da) 2022-08-01
MX2011006534A (es) 2011-07-13
US20120046643A1 (en) 2012-02-23
IL213575A0 (en) 2011-07-31
RU2514537C2 (ru) 2014-04-27
JP2012513266A (ja) 2012-06-14
US8945069B2 (en) 2015-02-03
HK1161850A1 (en) 2012-08-10
WO2010072662A1 (en) 2010-07-01
AU2009331633A1 (en) 2011-07-14
EP2381984B1 (en) 2022-05-11
ZA201103877B (en) 2012-01-25
RU2011130897A (ru) 2013-01-27
SG172319A1 (en) 2011-07-28

Similar Documents

Publication Publication Date Title
JP2012513266A (ja) 再設定可能な駆動機構を備えた固定用量注射デバイス
US10980947B2 (en) Drive and dosing device with a stop element for preventing the setting of a dose
US9855388B2 (en) Dosing and drive mechanism for drug delivery device
JP6371834B2 (ja) 動かされるカートリッジホルダおよびピストンロッド結合具を有する前方装填式の薬剤送達装置
JP5805092B2 (ja) 注射デバイス
DK2414004T3 (en) Improvements in and relating to devices for drug feed
JP4903160B2 (ja) ペン型薬物注入デバイス
JP5606445B2 (ja) 薬物送達デバイスにおける使用に適する駆動アセンブリ及び薬物送達デバイス
AU2011208616B2 (en) Drive assembly for a drug delivery device and drug delivery device
JP6382956B2 (ja) 動的な軸方向ストッパ特徴を有する前方装填式の薬剤送達装置
JP6316945B2 (ja) ピストンロッド結合具を有する薬剤送達装置
JP2018521788A (ja) ねじりばね駆動型注射デバイス
JP5982387B2 (ja) 薬剤送達デバイスのための駆動機構および薬剤送達デバイス
CN107847681A (zh) 药物输送装置
HK1161850B (en) Fixed dose injection device with resettable drive mechanism
HK40002923A (en) Method of assembly of drug delivery devices

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121210

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20121210

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20131126

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131210

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140306

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140701

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140728

R150 Certificate of patent or registration of utility model

Ref document number: 5588998

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250