JP5933454B2 - 薬物送達デバイス用の駆動アセンブリ及び薬物送達デバイス - Google Patents
薬物送達デバイス用の駆動アセンブリ及び薬物送達デバイス Download PDFInfo
- Publication number
- JP5933454B2 JP5933454B2 JP2012549375A JP2012549375A JP5933454B2 JP 5933454 B2 JP5933454 B2 JP 5933454B2 JP 2012549375 A JP2012549375 A JP 2012549375A JP 2012549375 A JP2012549375 A JP 2012549375A JP 5933454 B2 JP5933454 B2 JP 5933454B2
- Authority
- JP
- Japan
- Prior art keywords
- guide nut
- locking means
- drive assembly
- piston rod
- cartridge holder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Details Of Spanners, Wrenches, And Screw Drivers And Accessories (AREA)
- Automatic Assembly (AREA)
Description
Claims (11)
- 駆動アセンブリの軸の周囲を回転可能である、ガイドナット(4);
ガイドナットと係合し、ガイドナットの回転を阻止するために、軸に対して半径方向に可動である、ロッキング手段(9);
中にガイドナット及びロッキング手段が配置され、そのロッキング手段が締結される、本体(3);
ピストンロッド(17);
本体に取り付け可能で、及び本体から取り外し可能なカートリッジホルダ(2);及び
カートリッジホルダの一部であるか、又はカートリッジホルダに締結され、ロッキング手段を軸に対して半径方向に動かし、カートリッジホルダが本体に取り付けられたとき、ロッキング手段をガイドナットと係合させ、薬物送達のためにロッキング手段をガイドナットと係合する位置にロッキング手段を保持するように備え付けられる、ファスナ(14);
を含んでなる、薬物送達デバイス用の駆動アセンブリであって:
ガイドナット及びピストンロッドを連結させるねじ山(8、15)は、ガイドナットに対してピストンロッドの軸の周囲の回転及び軸に沿った同時シフトを含んでなるらせん運動を可能にし;
ファスナは、カートリッジホルダの突出部分であり;
ファスナは、ロッキング手段上を摺動するために作られ、及びロッキング手段を本体に対するカートリッジホルダの回転によりガイドナットと係合させ;
ファスナ(14)はガイドナット(4)と同心円である円上を移動し、ロッキング手段(9)はファスナ(14)の移動により半径方向に動かされる
ことを特徴とする、駆動アセンブリ。 - ガイドナット(4)が、歯の間にノッチ又は隙間を有する歯車であり、そして
ロッキング手段が、弾性的な又は弾性的に取り付けられた、ノッチ又は隙間を係合する端部又はフックを含むつめ又はカンチレバーである、請求項1に記載の駆動アセンブリ。 - ファスナ(14)が、カートリッジホルダ(2)の突出エレメントで提供される、請求
項1又は2に記載の駆動アセンブリ。 - ロッキング手段(9)は、カートリッジホルダが本体(3)に取り付けられていない場合、リセット操作中、ガイドナット(4)と係合しない、請求項1〜3のいずれか1項に記載の駆動アセンブリ。
- ロッキング手段がガイドナットに係合されていないとき、軸方向へのガイドナット(4)の動きを阻止するが、軸の周囲でガイドナットを回転することを可能とする、本体(3)のウェブ(32)を更に含んでなる、請求項1〜4のいずれか1項に記載の駆動アセンブリ。
- 本体(3)内に配置された駆動スリーブ(19)(その駆動スリーブは、更なるねじ山(16)によってピストンロッド(17)に連結される)を更に含んでなる、請求項5に記載の駆動アセンブリ。
- ねじ山(8、15)及び更なるねじ山(16)が反対方向の回転を有する、請求項6に記載の駆動アセンブリ。
- クラッチ(24)を更に含んでなり、駆動スリーブ(19)が該クラッチにより解除可能な方法で本体(3)に対して回転がロックされる、請求項6又は7に記載の駆動アセンブリ。
- 軸に沿った本体(3)に対して駆動スリーブ(19)のシフトは、駆動スリーブが本体に対して回転ロックされ、ロッキング手段(9)がガイドナット(4)に係合したとき、本体に対するピストンロッド(17)のらせん運動に変換される、請求項8に記載の駆動アセンブリ。
- 請求項1〜9のいずれか1項に記載の駆動アセンブリを含む薬物送達デバイス。
- 注射ペンの形状を有する請求項10に記載の薬物送達デバイス。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10151498 | 2010-01-25 | ||
EP10151498.2 | 2010-01-25 | ||
US30559610P | 2010-02-18 | 2010-02-18 | |
US61/305,596 | 2010-02-18 | ||
PCT/EP2011/050898 WO2011089246A1 (en) | 2010-01-25 | 2011-01-24 | Drive assembly for a drug delivery device and drug delivery device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013517821A JP2013517821A (ja) | 2013-05-20 |
JP5933454B2 true JP5933454B2 (ja) | 2016-06-08 |
Family
ID=42342510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012549375A Expired - Fee Related JP5933454B2 (ja) | 2010-01-25 | 2011-01-24 | 薬物送達デバイス用の駆動アセンブリ及び薬物送達デバイス |
Country Status (19)
Country | Link |
---|---|
US (1) | US10188800B2 (ja) |
EP (1) | EP2528643A1 (ja) |
JP (1) | JP5933454B2 (ja) |
KR (1) | KR101773347B1 (ja) |
CN (2) | CN104436374B (ja) |
AR (1) | AR079966A1 (ja) |
AU (1) | AU2011208616B2 (ja) |
BR (1) | BR112012018270A2 (ja) |
CA (1) | CA2784773A1 (ja) |
HK (1) | HK1208393A1 (ja) |
IL (1) | IL220999A (ja) |
MX (1) | MX2012008586A (ja) |
MY (1) | MY157474A (ja) |
NZ (1) | NZ602205A (ja) |
RU (1) | RU2012136463A (ja) |
SG (1) | SG182674A1 (ja) |
TW (1) | TW201138882A (ja) |
WO (1) | WO2011089246A1 (ja) |
ZA (1) | ZA201204466B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10188800B2 (en) | 2010-01-25 | 2019-01-29 | Sanofi-Aventis Deutschland Gmbh | Drive assembly for a drug delivery device and drug delivery device |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR086256A1 (es) * | 2011-05-06 | 2013-11-27 | Sanofi Aventis Deutschland | Conjunto de impulso para un dispositivo de administracion de farmacos y correspondiente dispositivo de administracion de farmacos |
DK2788053T3 (en) * | 2011-12-06 | 2017-01-23 | Shl Group Ab | Drug delivery device |
EP2869874B1 (en) | 2012-07-06 | 2018-12-12 | SHL Medical AG | Medicament delivery device |
WO2014005807A1 (en) * | 2012-07-06 | 2014-01-09 | Carebay Europe Ltd | Medicament delivery device |
AR097821A1 (es) | 2013-09-03 | 2016-04-20 | Sanofi Sa | Mecanismo de accionamiento |
US10485927B2 (en) | 2015-07-01 | 2019-11-26 | Novo Nordisk A/S | Method for assembling a drug delivery device and drug delivery device formed by the method |
JP1629334S (ja) * | 2017-10-25 | 2019-04-15 | ||
USD867588S1 (en) * | 2018-05-22 | 2019-11-19 | Sanofi | Cap of an injection device |
KR102271959B1 (ko) * | 2020-11-03 | 2021-07-02 | (주)풍림파마텍 | 도즈 다이얼을 통해 회전력이 가해진 토션 스프링의 꼬임을 일시적으로 유지하게 하는 약물 투입 조절 장치 |
KR102256035B1 (ko) * | 2020-11-03 | 2021-05-26 | (주)풍림파마텍 | 도즈 다이얼 사용 중 즉시적인 피드백을 가능하게 하는 약물 투입 조절 장치 |
KR102271965B1 (ko) * | 2020-11-03 | 2021-07-02 | (주)풍림파마텍 | 피스톤 로드에 스크류 결합된 로드 락이 로드 홀더 내부에 회전 제한된 상태에서 직선 운동 가능한 구조를 갖는 약물 투입 조절 장치 |
KR102224582B1 (ko) * | 2020-11-03 | 2021-03-09 | (주)풍림파마텍 | 도즈 다이얼 내에 배치된 버튼 플레이트를 통해 주입 버튼의 안정적인 동작구조를 갖는 약물 투입 조절 장치 |
KR102211181B1 (ko) * | 2020-11-03 | 2021-02-03 | (주)풍림파마텍 | 피스톤 로드와 로드 가이드 간의 스크류 방식 결합을 통한 카트리지 약물 방출 구조를 갖는 약물 투입 조절 장치 |
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GB9007113D0 (en) | 1990-03-29 | 1990-05-30 | Sams Bernard | Dispensing device |
EP0525525B1 (de) | 1991-07-24 | 1995-05-03 | Medico Development Investment Company | Injektor |
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US6899699B2 (en) | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
JP4283545B2 (ja) | 2001-05-16 | 2009-06-24 | イーライ リリー アンド カンパニー | リセット簡易化式駆動アセンブリー付きの薬物注射装置 |
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TW201138882A (en) | 2010-01-25 | 2011-11-16 | Sanofi Aventis Deutschland | Drive assembly for a drug delivery device and drug delivery device |
-
2011
- 2011-01-21 TW TW100102206A patent/TW201138882A/zh unknown
- 2011-01-24 MX MX2012008586A patent/MX2012008586A/es not_active Application Discontinuation
- 2011-01-24 NZ NZ602205A patent/NZ602205A/en not_active IP Right Cessation
- 2011-01-24 CA CA2784773A patent/CA2784773A1/en not_active Abandoned
- 2011-01-24 AU AU2011208616A patent/AU2011208616B2/en not_active Ceased
- 2011-01-24 WO PCT/EP2011/050898 patent/WO2011089246A1/en active Application Filing
- 2011-01-24 CN CN201410736092.XA patent/CN104436374B/zh not_active Expired - Fee Related
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10188800B2 (en) | 2010-01-25 | 2019-01-29 | Sanofi-Aventis Deutschland Gmbh | Drive assembly for a drug delivery device and drug delivery device |
Also Published As
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HK1208393A1 (en) | 2016-03-04 |
AU2011208616B2 (en) | 2014-10-23 |
CN104436374A (zh) | 2015-03-25 |
SG182674A1 (en) | 2012-08-30 |
AU2011208616A1 (en) | 2012-08-09 |
CN104436374B (zh) | 2018-02-13 |
EP2528643A1 (en) | 2012-12-05 |
MY157474A (en) | 2016-06-15 |
RU2012136463A (ru) | 2014-03-10 |
TW201138882A (en) | 2011-11-16 |
CN102711874A (zh) | 2012-10-03 |
IL220999A (en) | 2015-03-31 |
JP2013517821A (ja) | 2013-05-20 |
NZ602205A (en) | 2014-03-28 |
ZA201204466B (en) | 2013-02-27 |
IL220999A0 (en) | 2012-09-24 |
KR20120129923A (ko) | 2012-11-28 |
WO2011089246A1 (en) | 2011-07-28 |
CN102711874B (zh) | 2016-02-24 |
CA2784773A1 (en) | 2011-07-28 |
AR079966A1 (es) | 2012-02-29 |
BR112012018270A2 (pt) | 2016-05-03 |
KR101773347B1 (ko) | 2017-08-31 |
MX2012008586A (es) | 2012-11-23 |
US10188800B2 (en) | 2019-01-29 |
US20130030381A1 (en) | 2013-01-31 |
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