MX2011002874A - Novedosas formulaciones de carbapenem aminoglicosido como una sola unidad. - Google Patents

Novedosas formulaciones de carbapenem aminoglicosido como una sola unidad.

Info

Publication number
MX2011002874A
MX2011002874A MX2011002874A MX2011002874A MX2011002874A MX 2011002874 A MX2011002874 A MX 2011002874A MX 2011002874 A MX2011002874 A MX 2011002874A MX 2011002874 A MX2011002874 A MX 2011002874A MX 2011002874 A MX2011002874 A MX 2011002874A
Authority
MX
Mexico
Prior art keywords
carbapenem
single unit
bacterial
novel single
low
Prior art date
Application number
MX2011002874A
Other languages
English (en)
Inventor
Manu Chaudhary
Original Assignee
Manu Chaudhary
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manu Chaudhary filed Critical Manu Chaudhary
Publication of MX2011002874A publication Critical patent/MX2011002874A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a combinaciones antibióticas farmacéuticas de baja dosis de dos antibióticos seleccionados de dos grupos diferentes, es decir un carbapenem y un aminoglicósido presentes como una sola unidad para inyección de baja dosis fija, efectiva a muy bajas concentraciones para el tratamiento de infecciones bacterianas/ bacterianas múltiples particularmente adecuadas para neonatos, niños y otros pacientes con baja tolerancia que son tendientes a enfermedades infecciosas bacterianas múltiples mixtas serias y fatales, en donde una causa de consideración es toxicidad potencial debida a superiores dosis.
MX2011002874A 2008-09-18 2009-09-15 Novedosas formulaciones de carbapenem aminoglicosido como una sola unidad. MX2011002874A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2184DE2008 2008-09-18
PCT/IN2009/000508 WO2010032266A2 (en) 2008-09-18 2009-09-15 Novel single unit carbapenem aminoglycoside formulations

Publications (1)

Publication Number Publication Date
MX2011002874A true MX2011002874A (es) 2012-05-08

Family

ID=42039974

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011002874A MX2011002874A (es) 2008-09-18 2009-09-15 Novedosas formulaciones de carbapenem aminoglicosido como una sola unidad.

Country Status (12)

Country Link
US (1) US20110186457A1 (es)
EP (1) EP2334298B1 (es)
JP (1) JP2012502983A (es)
KR (1) KR20110058887A (es)
AU (1) AU2009294189A1 (es)
BR (1) BRPI0913709A2 (es)
CA (1) CA2737879C (es)
MX (1) MX2011002874A (es)
NZ (1) NZ591458A (es)
RU (1) RU2521391C2 (es)
WO (1) WO2010032266A2 (es)
ZA (1) ZA201102796B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101587420B1 (ko) * 2014-08-20 2016-01-22 주식회사 대웅제약 에르타페넴-함유 동결건조제제의 제조방법
GB201616909D0 (en) * 2016-10-05 2016-11-16 Helperby Therapeutics Ltd Combination
IL293883A (en) * 2019-12-14 2022-08-01 Manu Chaudhary Formulations of polybasic drugs to reduce multi-organ toxicity
CN111499670A (zh) * 2020-05-02 2020-08-07 无锡济民可信山禾药业股份有限公司 一种高纯度的3,2″,6″-三-n-乙酰基依替米星纯化方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757066A (en) * 1984-10-15 1988-07-12 Sankyo Company Limited Composition containing a penem or carbapenem antibiotic and the use of the same
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
CN1040177C (zh) * 1993-04-23 1998-10-14 江苏省微生物研究所 一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法
US6248360B1 (en) * 2000-06-21 2001-06-19 International Health Management Associates, Inc. Complexes to improve oral absorption of poorly absorbable antibiotics
US20070269539A1 (en) * 2003-05-02 2007-11-22 Georgetown University Ginkgo Biloba Extract as a Treatment for Therapeutic-Induced Neurotoxicity
EP2311847B9 (en) * 2003-10-01 2013-07-24 Daiichi Fine Chemical Co., Ltd. Composition containing stable vitamin b6 derivative
BRPI0517200A (pt) * 2004-12-17 2008-09-30 Venus Remedies Ltd combinações de antibióticos, processos de preparação de uma combinação de antibióticos e método de tratamento
EP1879589A2 (en) * 2005-05-13 2008-01-23 Venus Remedies Limited Treatment and control of severe infections including cystic fibrosis
NZ566460A (en) * 2005-09-15 2010-04-30 Orchid Chemicals & Pharm Ltd An improved process for the preparation of beta-lactam antibiotic
CN2905051Y (zh) * 2006-04-19 2007-05-30 吉林省一心制药有限公司 一种抗生素药物的预充式制剂
CN101129381B (zh) * 2006-08-25 2012-02-01 天津和美生物技术有限公司 含β-内酰胺类抗生素和离子螯合剂的抗生素复方
CN101129382B (zh) * 2006-08-25 2013-12-25 天津和美生物技术有限公司 含β-内酰胺类抗生素和缓冲组分的抗生素复方
CN101129383B (zh) * 2006-08-25 2014-04-02 天津和美生物技术有限公司 含氨基糖苷类抗生素的抗生素复方

Also Published As

Publication number Publication date
US20110186457A1 (en) 2011-08-04
CA2737879A1 (en) 2010-03-25
WO2010032266A2 (en) 2010-03-25
EP2334298B1 (en) 2014-07-30
KR20110058887A (ko) 2011-06-01
JP2012502983A (ja) 2012-02-02
BRPI0913709A2 (pt) 2015-10-13
WO2010032266A9 (en) 2011-05-12
WO2010032266A3 (en) 2010-06-24
EP2334298A2 (en) 2011-06-22
NZ591458A (en) 2012-07-27
RU2521391C2 (ru) 2014-06-27
CA2737879C (en) 2014-07-08
ZA201102796B (en) 2011-12-28
RU2011115132A (ru) 2012-10-27
AU2009294189A1 (en) 2010-03-25
WO2010032266A4 (en) 2010-08-26

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