MX2009005788A - Peptidos truncados de hormona paratiroidea con una conformacion ciclica. - Google Patents

Peptidos truncados de hormona paratiroidea con una conformacion ciclica.

Info

Publication number
MX2009005788A
MX2009005788A MX2009005788A MX2009005788A MX2009005788A MX 2009005788 A MX2009005788 A MX 2009005788A MX 2009005788 A MX2009005788 A MX 2009005788A MX 2009005788 A MX2009005788 A MX 2009005788A MX 2009005788 A MX2009005788 A MX 2009005788A
Authority
MX
Mexico
Prior art keywords
pth
pth peptides
cyclic conformation
truncated pth
truncated
Prior art date
Application number
MX2009005788A
Other languages
English (en)
Inventor
Bjarne Due Larsen
Carsten Boye Knudsen
Trine Skovlund Ryge
Martin Stahlhut
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Publication of MX2009005788A publication Critical patent/MX2009005788A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona péptidos de PTH que son análogos de substitución ciclizados del fragmento de PTH truncado PTH(1-17) y que preferentemente retiene la actividad biológica deseada o semejante de PTH(1-34) humano.
MX2009005788A 2006-12-08 2007-12-06 Peptidos truncados de hormona paratiroidea con una conformacion ciclica. MX2009005788A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87372306P 2006-12-08 2006-12-08
EP06025423A EP1961765A1 (en) 2006-12-08 2006-12-08 Truncated PTH peptides with a cyclic conformation
PCT/GB2007/004664 WO2008068487A1 (en) 2006-12-08 2007-12-06 Truncated pth peptides with a cyclic conformation

Publications (1)

Publication Number Publication Date
MX2009005788A true MX2009005788A (es) 2009-06-08

Family

ID=38230002

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005788A MX2009005788A (es) 2006-12-08 2007-12-06 Peptidos truncados de hormona paratiroidea con una conformacion ciclica.

Country Status (12)

Country Link
US (1) US20100048462A1 (es)
EP (2) EP1961765A1 (es)
JP (1) JP2010511686A (es)
KR (1) KR20090096506A (es)
CN (1) CN101600735A (es)
AU (1) AU2007330617B2 (es)
BR (1) BRPI0719874A2 (es)
CA (1) CA2670950A1 (es)
EA (1) EA200970465A1 (es)
MX (1) MX2009005788A (es)
NZ (1) NZ578227A (es)
WO (1) WO2008068487A1 (es)

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AU2008282805B2 (en) 2007-08-01 2014-05-01 Chugai Pharmaceutical Co., Ltd. Screening methods using G-protein coupled receptors and related compositions
WO2010111617A2 (en) 2009-03-27 2010-09-30 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
CN102405229A (zh) 2009-04-24 2012-04-04 卡迪拉保健有限公司 作为甲状旁腺激素(pth)受体激动剂的短链肽
HUE029371T2 (en) * 2009-11-27 2017-02-28 Genzyme Corp GENZ 112638 For treatment of Gaucher or Fabry disease in combination therapy
RU2604809C2 (ru) * 2010-05-13 2016-12-10 Дзе Дженерал Хоспитал Корпорейшн Аналоги паратиреоидного гормона и их применение
US20120184494A1 (en) * 2010-11-12 2012-07-19 Maurizio Zangari Multiple myeloma prognosis and treatment
WO2012120532A2 (en) 2011-02-02 2012-09-13 Cadila Healthcare Limited Cyclic short chain peptides
EP2709645B1 (en) * 2011-05-18 2023-08-09 Eumederis Pharmaceuticals, Inc. Improved peptide pharmaceuticals
EP2790717B1 (en) * 2011-12-14 2018-05-30 The Board of Trustees of the University of Arkansas Delivery of therapeutic agents by a collagen binding protein
JP6525456B2 (ja) 2012-11-20 2019-06-05 メデリス ダイアビーティーズ，エルエルシー インスリン抵抗性のための改善されたペプチド製剤
CN117180445A (zh) 2014-05-28 2023-12-08 梅德瑞斯糖尿病有限责任公司 针对胰岛素抵抗的改良肽药物
RS63143B1 (sr) 2016-06-01 2022-05-31 Athira Pharma Inc Jedinjenja
US11541028B2 (en) 2018-01-03 2023-01-03 Altimmune Inc. Peptide pharmaceuticals for treatment of NASH and other disorders
US20210206820A1 (en) * 2018-05-30 2021-07-08 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair

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US5624898A (en) * 1989-12-05 1997-04-29 Ramsey Foundation Method for administering neurologic agents to the brain
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Also Published As

Publication number Publication date
WO2008068487A1 (en) 2008-06-12
EP2054438A1 (en) 2009-05-06
NZ578227A (en) 2011-06-30
CA2670950A1 (en) 2008-06-12
BRPI0719874A2 (pt) 2014-04-15
EA200970465A1 (ru) 2010-02-26
AU2007330617A1 (en) 2008-06-12
US20100048462A1 (en) 2010-02-25
KR20090096506A (ko) 2009-09-10
EP1961765A1 (en) 2008-08-27
CN101600735A (zh) 2009-12-09
JP2010511686A (ja) 2010-04-15
AU2007330617B2 (en) 2012-11-29

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Legal Events

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FA Abandonment or withdrawal