MX2009004950A - Nuevos compuestos, composiciones farmaceuticas que contienen los mismos, y metodos de uso de los mismos. - Google Patents
Nuevos compuestos, composiciones farmaceuticas que contienen los mismos, y metodos de uso de los mismos.Info
- Publication number
- MX2009004950A MX2009004950A MX2009004950A MX2009004950A MX2009004950A MX 2009004950 A MX2009004950 A MX 2009004950A MX 2009004950 A MX2009004950 A MX 2009004950A MX 2009004950 A MX2009004950 A MX 2009004950A MX 2009004950 A MX2009004950 A MX 2009004950A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- same
- halogen
- optionally substituted
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
La presente invención se refiere a compuestos que tienen la siguiente fórmula general, composiciones farmacéuticas que comprenden los compuestos, y métodos para tratar cáncer, obesidad, e infección microbiana usando tales composiciones: en donde: R1 = H, alquilo de C1-C20, cicloalquilo, alquenilo, arilo, arilalquilo, o alquilarilo, cianometilo, -OCH3, -OC(O)CH3 o -OC(O)CF3, R2 = -OCH2C(O)NHNH-R5, donde R5 es (a) fenilo, opcionalmente sustituido con uno o más de halógeno, alquilo de C1-C8, opcionalmente sustituido con halógeno, -OH, -OR6, donde R6 es alquilo de C1-C8, opcionalmente sustituido con halógeno, o (b) 2-, 3-, o 4- piridilo, opcionalmente sustituido con halógeno, -OH, -OR6, donde R6 es alquilo de C1-C8, opcionalmente sustituido con halógeno, o (C) un heterociclo seleccionado del grupo que consiste de imidazol, tiazol, bencimidazol, benzoxazol, benztiazol, tetrazol, triazol, y aminotiazol; o (d) -C(O)R7, donde R7 es un alquilo de C1-C20, cicloalquilo, alquenilo, arilo, arilalquilo, o alquilarilo, o un heterociclo seleccionado del grupo que consiste de piridilo, imidazol, tiazol, bencimidazol, benzoxazol, benztiazol, tetrazol, triazol, y aminotiazol; y R3 y R4, los mismos o diferentes entre si, son alquilo de C1-C20, cicloalquilo, alquenilo, arilo, arilalquilo, o alquilarilo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85751306P | 2006-11-08 | 2006-11-08 | |
| PCT/US2007/023552 WO2008057585A1 (en) | 2006-11-08 | 2007-11-08 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009004950A true MX2009004950A (es) | 2009-07-27 |
Family
ID=39364833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009004950A MX2009004950A (es) | 2006-11-08 | 2007-11-08 | Nuevos compuestos, composiciones farmaceuticas que contienen los mismos, y metodos de uso de los mismos. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100168176A1 (es) |
| EP (1) | EP2086943A4 (es) |
| JP (1) | JP2010509335A (es) |
| KR (1) | KR20090098804A (es) |
| CN (1) | CN101611017A (es) |
| AU (1) | AU2007317794A1 (es) |
| BR (1) | BRPI0719058A2 (es) |
| CA (1) | CA2668840A1 (es) |
| EA (1) | EA200970460A1 (es) |
| IL (1) | IL198634A0 (es) |
| MX (1) | MX2009004950A (es) |
| WO (1) | WO2008057585A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009149066A1 (en) * | 2008-06-02 | 2009-12-10 | Fasgen, Inc. | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
| WO2010118324A2 (en) | 2009-04-09 | 2010-10-14 | Nuclea Biotechnologies, LLC | Antibodies against fatty acid synthase |
| WO2011140190A1 (en) | 2010-05-05 | 2011-11-10 | Infinity Pharmaceuticals | Tetrazolones as inhibitors of fatty acid synthase |
| US11202795B2 (en) | 2014-11-20 | 2021-12-21 | Vib Vzw | Means and methods for treatment of early-onset Parkinson's disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0000131D0 (en) * | 2000-01-06 | 2000-02-23 | Univ Cardiff | Thiolactomycin analogues,compositions containing the same and uses thereof |
| MXPA05000365A (es) * | 2002-07-09 | 2005-09-20 | Fasgen Llc | Nuevos compuestos, composiciones farmaceuticas que los contienen y metodos de uso de los mismos. |
-
2007
- 2007-11-08 CA CA002668840A patent/CA2668840A1/en not_active Abandoned
- 2007-11-08 US US12/513,888 patent/US20100168176A1/en not_active Abandoned
- 2007-11-08 CN CNA2007800445821A patent/CN101611017A/zh active Pending
- 2007-11-08 EA EA200970460A patent/EA200970460A1/ru unknown
- 2007-11-08 KR KR1020097011742A patent/KR20090098804A/ko not_active Application Discontinuation
- 2007-11-08 BR BRPI0719058-1A patent/BRPI0719058A2/pt not_active Application Discontinuation
- 2007-11-08 EP EP07853099A patent/EP2086943A4/en not_active Withdrawn
- 2007-11-08 AU AU2007317794A patent/AU2007317794A1/en not_active Abandoned
- 2007-11-08 WO PCT/US2007/023552 patent/WO2008057585A1/en active Search and Examination
- 2007-11-08 JP JP2009536300A patent/JP2010509335A/ja active Pending
- 2007-11-08 MX MX2009004950A patent/MX2009004950A/es unknown
-
2009
- 2009-05-07 IL IL198634A patent/IL198634A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2086943A1 (en) | 2009-08-12 |
| IL198634A0 (en) | 2010-02-17 |
| EA200970460A1 (ru) | 2009-12-30 |
| WO2008057585A1 (en) | 2008-05-15 |
| US20100168176A1 (en) | 2010-07-01 |
| BRPI0719058A2 (pt) | 2013-11-26 |
| CN101611017A (zh) | 2009-12-23 |
| CA2668840A1 (en) | 2008-05-15 |
| AU2007317794A1 (en) | 2008-05-15 |
| KR20090098804A (ko) | 2009-09-17 |
| JP2010509335A (ja) | 2010-03-25 |
| EP2086943A4 (en) | 2010-08-11 |
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