ATE480239T1 - Angiogeneseinhibitoren - Google Patents
AngiogeneseinhibitorenInfo
- Publication number
- ATE480239T1 ATE480239T1 AT05812885T AT05812885T ATE480239T1 AT E480239 T1 ATE480239 T1 AT E480239T1 AT 05812885 T AT05812885 T AT 05812885T AT 05812885 T AT05812885 T AT 05812885T AT E480239 T1 ATE480239 T1 AT E480239T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- optionally substituted
- alkyl
- hydrogen
- compounds
- Prior art date
Links
- 229940121369 angiogenesis inhibitor Drugs 0.000 title 1
- 239000004037 angiogenesis inhibitor Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 101100516568 Caenorhabditis elegans nhr-7 gene Chemical group 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CH2005/000321 WO2005120513A1 (en) | 2004-06-09 | 2005-06-09 | Protein kinase inhibitors |
| PCT/CH2005/000736 WO2006131003A1 (en) | 2005-06-09 | 2005-12-09 | Angiogenesis inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480239T1 true ATE480239T1 (de) | 2010-09-15 |
Family
ID=35636719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05812885T ATE480239T1 (de) | 2005-06-09 | 2005-12-09 | Angiogeneseinhibitoren |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1901748B1 (de) |
| AT (1) | ATE480239T1 (de) |
| AU (1) | AU2005332594A1 (de) |
| CA (1) | CA2611391A1 (de) |
| DE (1) | DE602005023544D1 (de) |
| WO (1) | WO2006131003A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009539840A (ja) * | 2006-06-06 | 2009-11-19 | シェーリング コーポレイション | プロテインキナーゼ阻害剤としてのイミダゾピラジン |
| WO2008141239A1 (en) * | 2007-05-10 | 2008-11-20 | Acadia Pharmaceuticals Inc. | Imidazol [1,2-a] pyridines and related compounds with activity at cannabinoid cb2 receptors |
| WO2010083617A1 (en) | 2009-01-21 | 2010-07-29 | Oncalis Ag | Pyrazolopyrimidines as protein kinase inhibitors |
| WO2011009695A1 (en) | 2009-07-21 | 2011-01-27 | Universität Zürich | New anti-angiogenic compounds |
| LT3105218T (lt) | 2014-02-13 | 2019-12-10 | Incyte Corp | Ciklopropilaminai kaip lsd1 inhibitoriai |
| WO2015123424A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| EP3392244A1 (de) | 2014-02-13 | 2018-10-24 | Incyte Corporation | Cyclopropylamine als lsd1-inhibitoren |
| US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
| WO2016007736A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyrazines as lsd1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| EA201792205A1 (ru) | 2015-04-03 | 2018-02-28 | Инсайт Корпорейшн | Гетероциклические соединения как ингибиторы lsd1 |
| DK3334709T3 (da) | 2015-08-12 | 2025-02-03 | Incyte Holdings Corp | Salte af en lsd1-hæmmer |
| CA3021678A1 (en) | 2016-04-22 | 2017-10-26 | Incyte Corporation | Formulations of an lsd1 inhibitor |
| CA3075813A1 (en) | 2017-10-04 | 2019-04-11 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibition of transcription factor sall4 and uses thereof |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100756592B1 (ko) * | 1999-10-08 | 2007-09-10 | 그뤼넨탈 게엠베하 | 비사이클릭 이미다조-3-일-아민 유도체, 이의 제조방법 및 이를 포함하는 진통제 |
-
2005
- 2005-12-09 WO PCT/CH2005/000736 patent/WO2006131003A1/en not_active Ceased
- 2005-12-09 AT AT05812885T patent/ATE480239T1/de not_active IP Right Cessation
- 2005-12-09 EP EP05812885A patent/EP1901748B1/de not_active Expired - Lifetime
- 2005-12-09 AU AU2005332594A patent/AU2005332594A1/en not_active Abandoned
- 2005-12-09 CA CA002611391A patent/CA2611391A1/en not_active Abandoned
- 2005-12-09 DE DE602005023544T patent/DE602005023544D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2611391A1 (en) | 2006-12-14 |
| EP1901748B1 (de) | 2010-09-08 |
| AU2005332594A1 (en) | 2006-12-14 |
| DE602005023544D1 (de) | 2010-10-21 |
| WO2006131003A1 (en) | 2006-12-14 |
| EP1901748A1 (de) | 2008-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602005023544D1 (de) | Angiogeneseinhibitoren | |
| EA201000100A1 (ru) | Гетероциклические соединения, полезные в качестве ингибиторов mk2 | |
| EA201290260A1 (ru) | Бензимидазол-имидазольные производные | |
| EA201101566A1 (ru) | Производные имидазола и их применение в качестве модуляторов циклинзависимых киназ | |
| NO20082934L (no) | Antivirale nukleotider | |
| CY1108792T1 (el) | Παραγωγα διοξανιου-2-αλκυλκαρβαμικου, η παρασκευη τους και η εφαρμογη τους στην θεραπευτικη αγωγη | |
| EA201000947A1 (ru) | Производные тиазола, применимые в качестве ингибиторов киназы pi3 | |
| AR054799A1 (es) | Derivados de oxindol | |
| EA201000113A1 (ru) | Пиразольные соединения | |
| EA201000750A1 (ru) | Производные 4-бензиламино-1-карбоксиацилпиперидина, как ингибиторы бпхэ (белка-переносчика холестериловогоэфира), применимые для лечения заболеваний, таких как гиперлипидемия или артериосклероз | |
| HRP20050533A2 (en) | Aminoindazole derivatives and use thereof as kinase inhibitors | |
| DE602006007012D1 (de) | Pyridinderivate als dipeptedyl-peptidase-hemmer | |
| CY1115536T1 (el) | Νεες υδροξυ-6-ετεροαρυλφαινανθριδινες και χρηση αυτων ως αναστολεις pde4 | |
| AR052866A1 (es) | Fenil-metanonas monociclicas sustituidas | |
| MX2009010909A (es) | Derivados de ftalazino y su uso como medicamento para tratar el cancer. | |
| EA201000101A1 (ru) | Производные пиримидина 934 | |
| CY1112679T1 (el) | Κινολινες και θεραπευτικη χρηση αυτων | |
| EA201071012A1 (ru) | Производные азетидинов, способ их получения и применение их в терапии | |
| DE602007001463D1 (de) | Pyrimidin-, chinazolin-, pteridin- und triazinderivate | |
| DE602005014804D1 (de) | Substituierte 5-carboxyamidpyrazoles und ä1,2,4ütriazole als viruzide | |
| UA107689C2 (xx) | ПОХІДНІ 3,4,4A,10B-ТЕТРАГІДРО-1H-ТІОПІРАНО$4, 3-c]ІЗОХІНОЛІНУ | |
| EA200701779A1 (ru) | Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии | |
| EA200702058A1 (ru) | Новые фармацевтические соединения | |
| EA201070010A1 (ru) | Производные 7-алкинил-1,8-нафтиридонов, их получение и их применение в терапии | |
| ATE492534T1 (de) | 1h-indol-5-ylpiperazin-1-ylmethanonderivate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |