ATE480239T1 - Angiogeneseinhibitoren - Google Patents
AngiogeneseinhibitorenInfo
- Publication number
- ATE480239T1 ATE480239T1 AT05812885T AT05812885T ATE480239T1 AT E480239 T1 ATE480239 T1 AT E480239T1 AT 05812885 T AT05812885 T AT 05812885T AT 05812885 T AT05812885 T AT 05812885T AT E480239 T1 ATE480239 T1 AT E480239T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- optionally substituted
- alkyl
- hydrogen
- compounds
- Prior art date
Links
- 229940121369 angiogenesis inhibitor Drugs 0.000 title 1
- 239000004037 angiogenesis inhibitor Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 101100516568 Caenorhabditis elegans nhr-7 gene Chemical group 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CH2005/000321 WO2005120513A1 (en) | 2004-06-09 | 2005-06-09 | Protein kinase inhibitors |
| PCT/CH2005/000736 WO2006131003A1 (en) | 2005-06-09 | 2005-12-09 | Angiogenesis inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480239T1 true ATE480239T1 (de) | 2010-09-15 |
Family
ID=35636719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05812885T ATE480239T1 (de) | 2005-06-09 | 2005-12-09 | Angiogeneseinhibitoren |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1901748B1 (de) |
| AT (1) | ATE480239T1 (de) |
| AU (1) | AU2005332594A1 (de) |
| CA (1) | CA2611391A1 (de) |
| DE (1) | DE602005023544D1 (de) |
| WO (1) | WO2006131003A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808802A (en) | 2006-06-06 | 2008-02-16 | Schering Corp | Imidazopyrazines as protein kinase inhibitors |
| ES2395583T3 (es) * | 2007-05-10 | 2013-02-13 | Ge Healthcare Limited | IMIDAZOL (1,2-A)PIRIDINAS y compuestos relacionados con actividad frente a los receptores cannabinoides CB2 |
| WO2010083617A1 (en) | 2009-01-21 | 2010-07-29 | Oncalis Ag | Pyrazolopyrimidines as protein kinase inhibitors |
| WO2011009695A1 (en) | 2009-07-21 | 2011-01-27 | Universität Zürich | New anti-angiogenic compounds |
| US9493442B2 (en) | 2014-02-13 | 2016-11-15 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| BR112016018555B1 (pt) | 2014-02-13 | 2024-01-23 | Incyte Holdings Corporation | Ciclopropilaminas como inibidores de lsd1, seu uso, composição farmacêutica que os compreende e método de inibição de lsd1 |
| CN106164066B (zh) | 2014-02-13 | 2020-01-17 | 因赛特公司 | 作为lsd1抑制剂的环丙胺 |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| WO2016007727A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| TW201613925A (en) | 2014-07-10 | 2016-04-16 | Incyte Corp | Imidazopyrazines as LSD1 inhibitors |
| ES2757948T3 (es) | 2015-04-03 | 2020-04-30 | Incyte Corp | Compuestos heterocíclicos como inhibidores LSD1 |
| CN110402244B (zh) | 2015-08-12 | 2023-02-03 | 因赛特公司 | Lsd1抑制剂的盐 |
| US10166221B2 (en) | 2016-04-22 | 2019-01-01 | Incyte Corporation | Formulations of an LSD1 inhibitor |
| JP2020536853A (ja) | 2017-10-04 | 2020-12-17 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | 転写因子ｓａｌｌ４の小分子阻害およびその使用 |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2213611T3 (es) * | 1999-10-08 | 2004-09-01 | Grunenthal Gmbh | Derivados biciclicos de imidazo-3-il-amina. |
-
2005
- 2005-12-09 EP EP05812885A patent/EP1901748B1/de not_active Expired - Lifetime
- 2005-12-09 CA CA002611391A patent/CA2611391A1/en not_active Abandoned
- 2005-12-09 AU AU2005332594A patent/AU2005332594A1/en not_active Abandoned
- 2005-12-09 DE DE602005023544T patent/DE602005023544D1/de not_active Expired - Lifetime
- 2005-12-09 AT AT05812885T patent/ATE480239T1/de not_active IP Right Cessation
- 2005-12-09 WO PCT/CH2005/000736 patent/WO2006131003A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006131003A1 (en) | 2006-12-14 |
| EP1901748A1 (de) | 2008-03-26 |
| EP1901748B1 (de) | 2010-09-08 |
| AU2005332594A1 (en) | 2006-12-14 |
| DE602005023544D1 (de) | 2010-10-21 |
| CA2611391A1 (en) | 2006-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |