MX2009003200A - Procedimiento para la preparacion de pradofloxacino. - Google Patents

Procedimiento para la preparacion de pradofloxacino.

Info

Publication number
MX2009003200A
MX2009003200A MX2009003200A MX2009003200A MX2009003200A MX 2009003200 A MX2009003200 A MX 2009003200A MX 2009003200 A MX2009003200 A MX 2009003200A MX 2009003200 A MX2009003200 A MX 2009003200A MX 2009003200 A MX2009003200 A MX 2009003200A
Authority
MX
Mexico
Prior art keywords
pradofloxacin
producing
substituent
improved method
solvent mixture
Prior art date
Application number
MX2009003200A
Other languages
English (en)
Inventor
Ralf Wischnat
Thomas Adam
Klaus Weidemann
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of MX2009003200A publication Critical patent/MX2009003200A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

La invención se refiere a un procedimiento mejorado para la preparación de pradofloxacino, en el que se introduce el sustituyente en la posición 7 mediante sustitución nucleófila en una mezcla de disolventes de N-metilpirrolidona y etanol.
MX2009003200A 2006-10-20 2007-10-06 Procedimiento para la preparacion de pradofloxacino. MX2009003200A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006049520A DE102006049520A1 (de) 2006-10-20 2006-10-20 Verfahren zur Herstellung von Pradofloxacin
PCT/EP2007/008687 WO2008046532A1 (de) 2006-10-20 2007-10-06 Verfahren zur herstellung von pradofloxacin

Publications (1)

Publication Number Publication Date
MX2009003200A true MX2009003200A (es) 2009-04-07

Family

ID=38982832

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003200A MX2009003200A (es) 2006-10-20 2007-10-06 Procedimiento para la preparacion de pradofloxacino.

Country Status (22)

Country Link
US (1) US8497377B2 (es)
EP (1) EP2086976B1 (es)
JP (2) JP5830221B2 (es)
AR (1) AR063227A1 (es)
AT (1) ATE509930T1 (es)
AU (1) AU2007312599B2 (es)
BR (1) BRPI0718480B8 (es)
CA (1) CA2666932C (es)
CL (1) CL2007003007A1 (es)
DE (1) DE102006049520A1 (es)
DK (1) DK2086976T3 (es)
ES (1) ES2365637T3 (es)
MX (1) MX2009003200A (es)
NZ (1) NZ576333A (es)
PE (1) PE20081466A1 (es)
PL (1) PL2086976T3 (es)
PT (1) PT2086976E (es)
SI (1) SI2086976T1 (es)
TW (1) TW200823210A (es)
UY (1) UY30646A1 (es)
WO (1) WO2008046532A1 (es)
ZA (1) ZA200902530B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073112C (zh) 1996-02-23 2001-10-17 拜尔公司 任选取代的8－氰基－1－环丙基－7－(2,8－二氮杂双环[4.3.0]壬－8－基)－6－氟－1,4－二氢－4－氧代－3－喹啉羧酸及其衍生物
DE19717231A1 (de) 1997-04-24 1998-10-29 Bayer Ag 3-Cyano-2,4,5-trifluor-benzoylfluorid
DE19733243A1 (de) 1997-08-01 1999-02-04 Bayer Ag Verfahren zur Herstellung von 3-Cyano-2,4-dihalogen-5-fluor-benzoesäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE10134719A1 (de) 2001-07-17 2003-02-06 Bayer Ag Pharmazeutische Zubereitungen enthaltend wirkstoffbeladene Ionentauscherharze
DE10224086A1 (de) 2002-05-31 2003-12-11 Bayer Ag Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
DE10312346A1 (de) 2003-03-20 2004-09-30 Bayer Healthcare Ag Kontrolliertes Freisetzungssystem
DE10337191A1 (de) 2003-08-13 2005-03-17 Bayer Healthcare Ag Neue Verwendung von Chinolon-Antibiotika
DE10351448A1 (de) 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
DE102005055385A1 (de) 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin

Also Published As

Publication number Publication date
PE20081466A1 (es) 2008-12-18
EP2086976B1 (de) 2011-05-18
TW200823210A (en) 2008-06-01
PT2086976E (pt) 2011-07-27
PL2086976T3 (pl) 2011-10-31
SI2086976T1 (sl) 2011-09-30
CA2666932C (en) 2015-03-10
JP2016028055A (ja) 2016-02-25
ES2365637T3 (es) 2011-10-07
EP2086976A1 (de) 2009-08-12
NZ576333A (en) 2011-12-22
BRPI0718480A2 (pt) 2014-02-18
UY30646A1 (es) 2008-05-31
JP5830221B2 (ja) 2015-12-09
CL2007003007A1 (es) 2008-04-04
AU2007312599B2 (en) 2013-11-14
US8497377B2 (en) 2013-07-30
JP2010506865A (ja) 2010-03-04
ZA200902530B (en) 2010-07-28
US20090318700A1 (en) 2009-12-24
CA2666932A1 (en) 2008-04-24
DK2086976T3 (da) 2011-09-05
BRPI0718480B1 (pt) 2021-04-13
DE102006049520A1 (de) 2008-04-24
AU2007312599A1 (en) 2008-04-24
AR063227A1 (es) 2009-01-14
ATE509930T1 (de) 2011-06-15
WO2008046532A1 (de) 2008-04-24
BRPI0718480B8 (pt) 2022-09-20

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