MX2009002066A - Analogos de 2-fenoxipirimidinona. - Google Patents
Analogos de 2-fenoxipirimidinona.Info
- Publication number
- MX2009002066A MX2009002066A MX2009002066A MX2009002066A MX2009002066A MX 2009002066 A MX2009002066 A MX 2009002066A MX 2009002066 A MX2009002066 A MX 2009002066A MX 2009002066 A MX2009002066 A MX 2009002066A MX 2009002066 A MX2009002066 A MX 2009002066A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- alkyl
- fluorophenyl
- purin
- hydrate
- Prior art date
Links
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| GB0509573D0 (en) * | 2005-05-11 | 2005-06-15 | Merck Sharp & Dohme | Therapeutic compounds |
| MX2009002066A (es) | 2006-08-23 | 2009-03-06 | Neurogen Corp | Analogos de 2-fenoxipirimidinona. |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| PE20160434A1 (es) | 2013-09-09 | 2016-05-25 | Peloton Therapeutics Inc | Eteres de arilo y sus usos |
| WO2016023830A1 (en) * | 2014-08-11 | 2016-02-18 | Hydra Biosciences, Inc. | Pyrido[2,3-d]pyrimidine-2,4(1h,3h)-dione derivatives |
| WO2016144825A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
| WO2016145032A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
| EP3268362B1 (en) | 2015-03-11 | 2021-10-20 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
| US10512626B2 (en) | 2015-03-11 | 2019-12-24 | Peloton Therapeautics, Inc. | Compositions for use in treating glioblastoma |
| WO2016168510A1 (en) | 2015-04-17 | 2016-10-20 | Peloton Therapeutics, Inc. | Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof |
| EP3908308A4 (en) * | 2019-01-08 | 2023-03-22 | Texas Tech University System | SMALL MOLECULE ANALOGUES OF PROTEIN E4ORF1 FOR THE TREATMENT AND PREVENTION OF METABOLIC DISORDERS |
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| US5124331A (en) | 1988-03-02 | 1992-06-23 | Yoshitomi Pharmaceutical Industries, Ltd. | 3,4-dihydrothieno[2,3-d]pyrimidine compounds and their pharmaceutical use |
| US5202328A (en) | 1991-03-06 | 1993-04-13 | Merck & Co., Inc. | Substituted fused pyrimidinones |
| ES2184960T3 (es) | 1996-05-15 | 2003-04-16 | Pfizer | Nuevas pirimidin-4-onas-(5,6)-heteroaril condensadas 2,3 disustituidas. |
| PL336581A1 (en) | 1997-05-08 | 2000-07-03 | Agrevo Uk Ltd | Fungicides |
| US6627755B1 (en) | 1997-06-09 | 2003-09-30 | Pfizer Inc | Quinazolin-4-one AMPA antagonists |
| US6323208B1 (en) | 1997-09-05 | 2001-11-27 | Pfizer Inc | Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones |
| IL125950A0 (en) | 1997-09-05 | 1999-04-11 | Pfizer Prod Inc | Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy |
| WO2002026718A2 (en) | 2000-09-29 | 2002-04-04 | Millennium Pharmaceutical, Inc. | Bicyclic pyrimidin-4-one based inhibitors of factor xa |
| JP2004518732A (ja) | 2001-02-14 | 2004-06-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | マトリックスメタロプロテイナーゼ阻害剤としてのチエノ’２，３−ｄピリミジンジオン誘導体 |
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| US6984647B2 (en) | 2002-05-17 | 2006-01-10 | Janssen Pharmaceutica N.V. | Aminotetralin-derived urea modulators of vanilloid VR1 receptor |
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| KR20050122220A (ko) | 2003-03-25 | 2005-12-28 | 다케다 샌디에고, 인코포레이티드 | 디펩티딜 펩티다제 억제제 |
| EP1687306A1 (en) * | 2003-11-14 | 2006-08-09 | MERCK SHARP & DOHME LTD. | Bicyclic pyrimidin-4-(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (vr1) |
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| US7544803B2 (en) * | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
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| AR051596A1 (es) * | 2004-10-26 | 2007-01-24 | Irm Llc | Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios |
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| CA2607929A1 (en) | 2005-05-11 | 2006-11-16 | Merck Sharp & Dohme Limited | 2,3-substituted fused bicyclic pyrimidin-4(3h)-ones modulating the function of the vanilloid-1 receptor (vr1) |
| CN1318429C (zh) * | 2005-07-25 | 2007-05-30 | 华中师范大学 | 具有杀菌活性的取代噻吩并[3',2':5,6]吡啶并[4,3－d]嘧啶－4(3H)－酮及制备 |
| US20100152209A1 (en) | 2005-11-04 | 2010-06-17 | Hydra Biosciences Inc. | Compounds for Modulating TRPV3 Function |
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| CN101558069A (zh) | 2006-11-06 | 2009-10-14 | 神经能质公司 | 顺式环己基取代的嘧啶酮衍生物 |
| WO2008156607A1 (en) | 2007-06-12 | 2008-12-24 | Neurogen Corporation | Substituted pyrimidinones |
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| US20120208829A1 (en) | 2012-08-16 |
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| CA2660957C (en) | 2016-10-11 |
| CR10675A (es) | 2009-04-17 |
| AU2007288203B2 (en) | 2013-01-17 |
| CO6150167A2 (es) | 2010-04-20 |
| EP2061794A2 (en) | 2009-05-27 |
| CN104292229A (zh) | 2015-01-21 |
| MA30720B1 (fr) | 2009-09-01 |
| BRPI0716582A2 (pt) | 2013-10-08 |
| WO2008024438A2 (en) | 2008-02-28 |
| IL197043A0 (en) | 2009-11-18 |
| CN101506210A (zh) | 2009-08-12 |
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| US8003656B2 (en) | 2011-08-23 |
| NI200900023A (es) | 2010-03-05 |
| CA2660957A1 (en) | 2008-02-28 |
| ES2399928T3 (es) | 2013-04-04 |
| KR20090043583A (ko) | 2009-05-06 |
| US8759361B2 (en) | 2014-06-24 |
| EA200900330A1 (ru) | 2009-08-28 |
| EP2061794A4 (en) | 2010-09-08 |
| EP2061794B1 (en) | 2012-12-05 |
| JP5421108B2 (ja) | 2014-02-19 |
| JP2010502576A (ja) | 2010-01-28 |
| WO2008024438A3 (en) | 2008-11-27 |
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